Native mu-conotoxin KIIIA isomer. Determined by solution NMR. Released 25 May 2022.
Explore 7SAV in 3D Show helices and sheets RCSB PDB PDBe
7SAV contains 1 α-helix and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 7-11 | 5 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Mu-conotoxin KIIIA | A | protein | 17 | Conus kinoshitai | P0C195 (AlphaFold model) |
>7SAV_1 Mu-conotoxin KIIIA (chains A) CCNCSSKWCRDHSRCCX
Structural and functional insights into the inhibition of human voltage-gated sodium channels by mu-conotoxin KIIIA disulfide isomers. Tran, H.N.T., McMahon, K.L., Deuis, J.R. et al. J Biol Chem (2022) 298:101728-101728. DOI 10.1016/j.jbc.2022.101728 · PubMed
Other PDB entries of the same protein (UniProt P0C195 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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