7W8B: Isoform 5 of Focal adhesion kinase 1

Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase. Determined by X-ray diffraction at 2.09 Å resolution. Released 5 Jul 2023.

Method
X-ray diffraction
Resolution
2.09 Å
Organism
Homo sapiens
Chains
1
Atoms
1,149
Mol. weight
18.28 kDa
Released
5 Jul 2023

Explore 7W8B in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7W8B contains 9 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 9 helices, 0 β-strands

ElementResiduesLengthSheet
α-helix914-9174
α-helix926-94520
α-helix947-9493
α-helix950-9523
α-helix953-97422
α-helix975-9773
α-helix980-9823
α-helix983-100927
α-helix1016-105237

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Isoform 5 of Focal adhesion kinase 1Aprotein164Homo sapiensQ05397 (AlphaFold model)
Sequence of entity 1 (A), FASTA
>7W8B_1 Isoform 5 of Focal adhesion kinase 1 (chains A)
SSPADSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPE
EYVPMVKEVGLALRTLLATVDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYV
MTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH

Primary citation

Crystal Structure of human Focal Adhesion Targeting (FAT) domain of the Focal Adhesion Kinase. Momin, A.A., Sandholu, A.S., Arold, S.T. To be published.

Other PDB entries of the same protein (UniProt Q05397 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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