7Z34: Pre-60S particle

Name: PDB 7Z34: Structure of pre-60S particle bound to DRG1(AFG2).
Published: 2022-09-21
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: ribosome

Structure of pre-60S particle bound to DRG1(AFG2). Determined by electron microscopy at 3.8 Å resolution. Released 21 Sept 2022.

Method: Electron microscopy
Resolution: 3.8 Å
Organisms: Saccharomyces cerevisiae S288C, Saccharomyces cerevisiae S288C ATCC 204508 / S288c
Chains: 58
Atoms: 177,847
Mol. weight: 2755.94 kDa
Ligands: MG, AGS
Released: 21 Sept 2022

Explore 7Z34 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

7Z34 contains 564 α-helices and 515 β-strands across 55 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain 0: 0 helices, 3 β-strands

Element	Residues	Length	Sheet
β-strand	-1	1	130
β-strand	1	1	157
β-strand	12	1	133

Chain 4: 19 helices, 24 β-strands

Element	Residues	Length	Sheet
α-helix	20-49	30
α-helix	61-76	16
β-strand	87-97	11	47
β-strand	100	1	48
α-helix	108-110	3
α-helix	111-118	8
α-helix	126-130	5
α-helix	133-134	2
β-strand	139-147	9	47
β-strand	150-158	9	47
α-helix	162-164	3
β-strand	176	1	49
α-helix	179-199	21
α-helix	220-234	15
β-strand	237	1	47
β-strand	243-247	5	47
β-strand	248	1	50
β-strand	251	1	50
β-strand	266-268	3	47
α-helix	289-291	3
α-helix	295-297	3
β-strand	316-324	9	47
β-strand	333-339	7	48
β-strand	360-361	2	51
α-helix	373-384	12
β-strand	390	1	51
α-helix	392-394	3
α-helix	407-428	22
β-strand	433-434	2	51
β-strand	438-444	7	48
α-helix	445-449	5
β-strand	453	1	46
β-strand	475	1	52
β-strand	480	1	52
α-helix	482-490	9
β-strand	497	1	48
β-strand	500-509	10	47
β-strand	522-525	4	47
α-helix	529-532	4
α-helix	533-535	3
β-strand	537	1	49
α-helix	550-561	12
β-strand	569-571	3	47

Chain a: 9 helices, 7 β-strands

Element	Residues	Length	Sheet
β-strand	10-11	2	60
β-strand	14-18	5	61
α-helix	22-24	3
α-helix	25-28	4
α-helix	39-49	11
β-strand	57-61	5	61
β-strand	64-65	2	60
β-strand	73-74	2	61
α-helix	77-84	8
α-helix	87-89	3
α-helix	102-105	4
α-helix	106-117	12
α-helix	125-139	15
β-strand	143	1	62
β-strand	146	1	62
α-helix	148-157	10

Chain A: 9 helices, 17 β-strands

Element	Residues	Length	Sheet
α-helix	6-9	4
β-strand	28	1	55
α-helix	29-32	4
α-helix	34-37	4
β-strand	40-49	10	55
α-helix	57	1
β-strand	58-64	7	55
α-helix	65	1
β-strand	71-77	7	55
β-strand	79	1	56
β-strand	82-83	2	57
β-strand	87-91	5	55
β-strand	100-103	4	55
α-helix	108	1
β-strand	112-114	3	55
β-strand	134-135	2	55
β-strand	136-140	5	58
α-helix	142-144	3
β-strand	145-149	5	58
β-strand	155-159	5	58
β-strand	163-166	4	55
α-helix	168	1
β-strand	169	1	56
α-helix	182-190	9
β-strand	224	1	59
β-strand	237	1	59

Chain Aa: 35 helices, 28 β-strands

Element	Residues	Length	Sheet
β-strand	35-37	3	1
β-strand	50-53	4	1
α-helix	55-61	7
β-strand	68-72	5	1
β-strand	78	1	2
β-strand	79-85	7	1
β-strand	95-97	3	1
α-helix	100-106	7
α-helix	108-109	2
β-strand	115-118	4	1
α-helix	122-124	3
β-strand	125	1	3
α-helix	126	1
β-strand	128-132	5	4
α-helix	145-155	11
β-strand	157-158	2	3
β-strand	163-164	2	4
β-strand	168	1	5
β-strand	175	1	5
β-strand	178-184	7	4
β-strand	210	1	2
β-strand	215-216	2	3
β-strand	223-226	4	4
α-helix	238-240	3
α-helix	251-266	16
α-helix	277-279	3
β-strand	282-285	4	6
α-helix	292-302	11
β-strand	306-310	5	6
α-helix	322-336	15
β-strand	340-345	6	6
α-helix	347-350	4
α-helix	361-374	14
β-strand	383-389	7	6
α-helix	397-400	4
β-strand	408-410	3	6
α-helix	416-426	11
α-helix	431-433	3
α-helix	441-448	8
α-helix	455-475	21
α-helix	488-494	7
α-helix	495-497	3
α-helix	501-505	5
α-helix	522-528	7
α-helix	529-533	5
α-helix	534-537	4
α-helix	539-545	7
α-helix	547-549	3
β-strand	553-556	4	7
α-helix	564-569	6
β-strand	578-580	3	8
α-helix	593-603	11
β-strand	612-614	3	8
β-strand	615-616	2	7
α-helix	618-620	3
α-helix	635-642	8
β-strand	656-658	3	7
α-helix	662-665	4
β-strand	679-680	2	7
α-helix	686-696	11
α-helix	709-715	7
α-helix	722-738	17
α-helix	747-754	8

Chain b: 25 helices, 11 β-strands

Element	Residues	Length	Sheet
α-helix	14-28	15
α-helix	39-67	29
α-helix	82-85	4
α-helix	89-117	29
α-helix	122-141	20
α-helix	144-158	15
β-strand	170-174	5	67
α-helix	181-187	7
β-strand	205-206	2	67
β-strand	209-211	3	68
β-strand	214-216	3	68
β-strand	218-220	3	67
α-helix	234-244	11
β-strand	249-253	5	67
α-helix	267-277	11
β-strand	283-286	4	67
β-strand	287	1	69
α-helix	290-293	4
α-helix	295-297	3
α-helix	300-310	11
β-strand	319	1	69
α-helix	327-345	19
α-helix	375-377	3
α-helix	380-383	4
α-helix	399-404	6
β-strand	435	1	70
β-strand	440	1	70
α-helix	441-443	3
α-helix	449-466	18
α-helix	483-511	29
α-helix	528-538	11
α-helix	543-546	4
α-helix	550-552	3
α-helix	563-568	6
α-helix	572-576	5
α-helix	596-616	21

Chain B: 10 helices, 14 β-strands

Element	Residues	Length	Sheet
α-helix	9-10	2
β-strand	47-61	15	64
β-strand	68-80	13	64
β-strand	84-95	12	65
β-strand	98-106	9	65
α-helix	112-118	7
α-helix	131-136	6
α-helix	144-153	10
β-strand	157-163	7	65
β-strand	178-182	5	65
α-helix	188-198	11
β-strand	202-203	2	65
β-strand	213-220	8	64
β-strand	226-227	2	66
α-helix	229-232	4
α-helix	235-238	4
α-helix	262-264	3
β-strand	268-269	2	66
β-strand	274-286	13	64
β-strand	321-325	5	64
β-strand	334-339	6	64
α-helix	348-350	3
β-strand	358-360	3	64
α-helix	373-380	8

Chain c: 4 helices, 4 β-strands

Element	Residues	Length	Sheet
α-helix	10-19	10
β-strand	21-25	5	76
α-helix	27-35	9
β-strand	41-45	5	76
α-helix	50-63	14
β-strand	66-70	5	76
α-helix	74-81	8
β-strand	89-95	7	76

47 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
ATPase family gene 2 protein	Aa, m, n, t, w, x	protein	780	Saccharomyces cerevisiae S288C	P32794 (AlphaFold model)
35S pre-ribosomal RNA	1	RNA	3396	Saccharomyces cerevisiae S288C
5S rRNA	2	RNA	121	Saccharomyces cerevisiae S288C
5.8S rRNA	3	RNA	158	Saccharomyces cerevisiae S288C
Probable metalloprotease ARX1	4	protein	593	Saccharomyces cerevisiae S288C	Q03862 (AlphaFold model)
60S ribosomal protein L2-A	A	protein	254	Saccharomyces cerevisiae S288C	P0CX45 (AlphaFold model)
60S ribosomal protein L3	B	protein	387	Saccharomyces cerevisiae S288C	P14126 (AlphaFold model)
60S ribosomal protein L4-A	C	protein	362	Saccharomyces cerevisiae S288C	P10664
60S ribosomal protein L5	D	protein	297	Saccharomyces cerevisiae S288C	P26321
60S ribosomal protein L6-A	E	protein	176	Saccharomyces cerevisiae S288C	Q02326
60S ribosomal protein L7-A	F	protein	244	Saccharomyces cerevisiae S288C	P05737
60S ribosomal protein L8-A	G	protein	256	Saccharomyces cerevisiae S288C	P17076

41 more molecules are not listed.

Sequence of entity 1 (Aa, m, n, t, w, x), FASTA

>7Z34_1 ATPase family gene 2 protein (chains Aa, m, n, t, w, x)
MAPKSSSSGSKKKSSASSNSADAKASKFKLPAEFITRPHPSKDHGKETCTAYIHPNVLSS
LEINPGSFCTVGKIGENGILVIARAGDEEVHPVNVITLSTTIRSVGNLILGDRLELKKAQ
VQPPYATKVTVGSLQGYNILECMEEKVIQKLLDDSGVIMPGMIFQNLKTKAGDESIDVVI
TDASDDSLPDVSQLDLNMDDMYGGLDNLFYLSPPFIFRKGSTHITFSKETQANRKYNLPE
PLSYAAVGGLDKEIESLKSAIEIPLHQPTLFSSFGVSPPRGILLHGPPGTGKTMLLRVVA
NTSNAHVLTINGPSIVSKYLGETEAALRDIFNEARKYQPSIIFIDEIDSIAPNRANDDSG
EVESRVVATLLTLMDGMGAAGKVVVIAATNRPNSVDPALRRPGRFDQEVEIGIPDVDARF
DILTKQFSRMSSDRHVLDSEAIKYIASKTHGYVGADLTALCRESVMKTIQRGLGTDANID
KFSLKVTLKDVESAMVDIRPSAMREIFLEMPKVYWSDIGGQEELKTKMKEMIQLPLEASE
TFARLGISAPKGVLLYGPPGCSKTLTAKALATESGINFLAVKGPEIFNKYVGESERAIRE
IFRKARSAAPSIIFFDEIDALSPDRDGSSTSAANHVLTSLLNEIDGVEELKGVVIVAATN
RPDEIDAALLRPGRLDRHIYVGPPDVNARLEILKKCTKKFNTEESGVDLHELADRTEGYS
GAEVVLLCQEAGLAAIMEDLDVAKVELRHFEKAFKGIARGITPEMLSYYEEFALRSGSSS

Sequence of entity 2 (1), FASTA

>7Z34_2 35S pre-ribosomal RNA (chains 1)
GUUUGACCUCAAAUCAGGUAGGAGUACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGA
AAAGAAACCAACCGGGAUUGCCUUAGUAACGGCGAGUGAAGCGGCAAAAGCUCAAAUUUG
AAAUCUGGUACCUUCGGUGCCCGAGUUGUAAUUUGGAGAGGGCAACUUUGGGGCCGUUCC
UUGUCUAUGUUCCUUGGAACAGGACGUCAUAGAGGGUGAGAAUCCCGUGUGGCGAGGAGU
GCGGUUCUUUGUAAAGUGCCUUCGAAGAGUCGAGUUGUUUGGGAAUGCAGCUCUAAGUGG
GUGGUAAAUUCCAUCUAAAGCUAAAUAUUGGCGAGAGACCGAUAGCGAACAAGUACAGUG
AUGGAAAGAUGAAAAGAACUUUGAAAAGAGAGUGAAAAAGUACGUGAAAUUGUUGAAAGG
GAAGGGCAUUUGAUCAGACAUGGUGUUUUGUGCCCUCUGCUCCUUGUGGGUAGGGGAAUC
UCGCAUUUCACUGGGCCAGCAUCAGUUUUGGUGGCAGGAUAAAUCCAUAGGAAUGUAGCU
UGCCUCGGUAAGUAUUAUAGCCUGUGGGAAUACUGCCAGCUGGGACUGAGGACUGCGACG
UAAGUCAAGGAUGCUGGCAUAAUGGUUAUAUGCCGCCCGUCUUGAAACACGGACCAAGGA
GUCUAACGUCUAUGCGAGUGUUUGGGUGUAAAACCCAUACGCGUAAUGAAAGUGAACGUA
GGUUGGGGCCUCGCAAGAGGUGCACAAUCGACCGAUCCUGAUGUCUUCGGAUGGAUUUGA
GUAAGAGCAUAGCUGUUGGGACCCGAAAGAUGGUGAACUAUGCCUGAAUAGGGUGAAGCC
AGAGGAAACUCUGGUGGAGGCUCGUAGCGGUUCUGACGUGCAAAUCGAUCGUCGAAUUUG
GGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCUGCCGAAGUUUCCCU
CAGGAUAGCAGAAGCUCGUAUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGAGGUUCCGGG
GUCGAAAUGACCUUGACCUAUUCUCAAACUUUAAAUAUGUAAGAAGUCCUUGUUACUUAA
UUGAACGUGGACAUUUGAAUGAAGAGCUUUUAGUGGGCCAUUUUUGGUAAGCAGAACUGG
CGAUGCGGGAUGAACCGAACGUAGAGUUAAGGUGCCGGAAUACACGCUCAUCAGACACCA
CAAAAGGUGUUAGUUCAUCUAGACAGCCGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAA
GGAGUGUGUAACAACUCACCGGCCGAAUGAACUAGCCCUGAAAAUGGAUGGCGCUCAAGC
GUGUUACCUAUACUCUACCGUCAGGGUUGAUAUGAUGCCCUGACGAGUAGGCAGGCGUGG
AGGUCAGUGACGAAGCCUAGACCGUAAGGUCGGGUCGAACGGCCUCUAGUGCAGAUCUUG
GUGGUAGUAGCAAAUAUUCAAAUGAGAACUUUGAAGACUGAAGUGGGGAAAGGUUCCACG
UCAACAGCAGUUGGACGUGGGUUAGUCGAUCCUAAGAGAUGGGGAAGCUCCGUUUCAAAG
GCCUGAUUUUAUGCAGGCCACCAUCGAAAGGGAAUCCGGUUAAGAUUCCGGAACCUGGAU
AUGGAUUCUUCACGGUAACGUAACUGAAUGUGGAGACGUCGGCGCGAGCCCUGGGAGGAG
UUAUCUUUUCUUCUUAACAGCUUAUCACCCCGGAAUUGGUUUAUCCGGAGAUGGGGUCUU
AUGGCUGGAAGAGGCCAGCACCUUUGCUGGCUCCGGUGCGCUUGUGACGGCCCGUGAAAA
UCCACAGGAAGGAAUAGUUUUCAUGCCAGGUCGUACUGAUAACCGCAGCAGGUCUCCAAG
GUGAACAGCCUCUAGUUGAUAGAAUAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGU
AACUUCGGGAUAAGGAUUGGCUCUAAGGGUCGGGUAGUGAGGGCCUUGGUCAGACGCAGC
GGGCGUGCUUGUGGACUGCUUGGUGGGGCUUGCUCUGCUAGGCGGACUACUUGCGUGCCU
UGUUGUAGACGGCCUUGGUAGGUCUCUUGUAGACCGUCGCUUGCUACAAUUAACGAUCAA
CUUAGAACUGGUACGGACAAGGGGAAUCUGACUGUCUAAUUAAAACAUAGCAUUGCGAUG
GUCAGAAAGUGAUGUUGACGCAAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAA
GAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAA
AUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAUUAACGAGAUUCCCACUGUCCCU
AUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGGCUUGGCAGAAUCAGCGGGGAAAG
AAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGAAGAGACAUAGAGGGUGUAGAAU
AAGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACCUUUAUAGUUUCUUUACUUAUUCAA
UGAAGCGGAGCUGGAAUUCAUUUUCCACGUUCUAGCAUUCAAGGUCCCAUUCGGGGCUGA
UCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGGCGGCACAUCUGUUAAACGA
UAACGCAGAUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAUCUCCAGUAGAACAAAAGGG
UAAAAGCCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACCAUGAAAGUGUGGCCUAUC
GAUCCUUUAGUCCCUCGGAAUUUGAGGCUAGAGGUGCCAGAAAAGUUACCACAGGGAUAA
CUGGCUUGUGGCAGUCAAGCGUUCAUAGCGACAUUGCUUUUUGAUUCUUCGAUGUCGGCU
CUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUGUUCACCCACUAAUAGGGA
ACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAAUGUUA
CCGCAAUAGUAAUUGAACUUAGUACGAGAGGAACAGUUCAUUCGGAUAAUUGGUUUUUGC
GGCUGUCUGAUCAGGCAUUGCCGCGAAGCUACCAUCCGCUGGAUUAUGGCUGAACGCCUC
UAAGUCAGAAUCCAUGCUAGAACGCGGUGAUUUCUUUGCUCCACACAAUAUAGAUGGAUA
CGAAUAAGGCGUCCUUGUGGCGUCGCUGAACCAUAGCAGGCUAGCAACGGUGCACUUGGC
GGAAAGGCCUUGGGUGCUUGCUGGCGAAUUGCAAUGUCAUUUUGCGUGGGGAUAAAUCAU
UUGUAUACGACUUAGAUGUACAACGGGGUAUUGUAAGCAGUAGAGUAGCCUUGUUGUUAC
GAUCUGCUGAGAUUAAGCCUUUGUUGUCUGAUUUGU

Sequence of entity 3 (2), FASTA

>7Z34_3 5S rRNA (chains 2)
GGUUGCGGCCAUAUCUACCAGAAAGCACCGUUUCCCGUCCGAUCAACUGUAGUUAAGCUG
GUAAGAGCCUGACCGAGUAGUGUAGUGGGUGACCAUACGCGAAACUCAGGUGCUGCAAUC
U

Sequence of entity 4 (3), FASTA

>7Z34_4 5.8S rRNA (chains 3)
AAACUUUCAACAACGGAUCUCUUGGUUCUCGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
ACGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCC
UUGGUAUUCCAGGGGGCAUGCCUGUUUGAGCGUCAUUU

Sequence of entity 5 (4), FASTA

>7Z34_5 Probable metalloprotease ARX1 (chains 4)
MALAISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLT
VPELCLLTDSFILTRLEQYYKNKVNERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWNKG
KDSTFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVIYPVDETKPILQPTGPLLGGK
ADAVAAAHIAMETVVALLACALTPEKLPASLGGTSSGITGQLIRTIVDTIARSYNCGVVP
GSRVRRIRRFLAGQNEGIVAEREYKGVVWTESHQEADLLSNTDAKDLTVVDRGQSTPFTN
VSAIPSDDFVVQSGEVYLIDLKMASLEHCTKKGLVTLETVDSYTGKSHKAGELIARPGAY
VRDFAQTHILKLKTSRQLLTKIDKQGVYPFKLSHLSSNFPFVHENEEELQSLKKDLKSFR
LGMSEISNNYLCVESPIQIARWVPWDHILKATNPNGNLSYDATSTLTLPGHELPLPKLGV
SAIKLKSLMNSTKESISLPVARECNTIVLCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQ
HELNPQDSIVQGIFQLATLAKDKRFGLLLKETQPMKQKSVETSNGGVEETMKM

Sequence of entity 6 (A), FASTA

>7Z34_6 60S ribosomal protein L2-A (chains A)
MGRVIRNQRKGAGSIFTSHTRLRQGAAKLRTLDYAERHGYIRGIVKQIVHDSGRGAPLAK
VVFRDPYKYRLREEIFIANEGVHTGQFIYAGKKASLNVGNVLPLGSVPEGTIVSNVEEKP
GDRGALARASGNYVIIIGHNPDENKTRVRLPSGAKKVISSDARGVIGVIAGGGRVDKPLL
KAGRAFHKYRLKRNSWPKTRGVAMNPVDHPHGGGNHQHIGKASTISRGAVSGQKAGLIAA
RRTGLLRGSQKTQD

Sequence of entity 7 (B), FASTA

>7Z34_7 60S ribosomal protein L3 (chains B)
MSHRKYEAPRHGHLGFLPRKRAASIRARVKAFPKDDRSKPVALTSFLGYKAGMTTIVRDL
DRPGSKFHKREVVEAVTVVDTPPVVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYK
NWYKSKKKAFTKYSAKYAQDGAGIERELARIKKYASVVRVLVHTQIRKTPLAQKKAHLAE
IQLNGGSISEKVDWAREHFEKTVAVDSVFEQNEMIDAIAVTKGHGFEGVTHRWGTKKLPR
KTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHSRTSINHKIYRVGKGDDEANGATSFDR
TKKTITPMGGFVHYGEIKNDFIMVKGCIPGNRKRIVTLRKSLYTNTSRKALEEVSLKWID
TASKFGKGRFQTPAEKHAFMGTLKKDL

Sequence of entity 8 (C), FASTA

>7Z34_8 60S ribosomal protein L4-A (chains C)
MSRPQVTVHSLTGEATANALPLPAVFSAPIRPDIVHTVFTSVNKNKRQAYAVSEKAGHQT
SAESWGTGRAVARIPRVGGGGTGRSGQGAFGNMCRGGRMFAPTKTWRKWNVKVNHNEKRY
ATASAIAATAVASLVLARGHRVEKIPEIPLVVSTDLESIQKTKEAVAALKAVGAHSDLLK
VLKSKKLRAGKGKYRNRRWTQRRGPLVVYAEDNGIVKALRNVPGVETANVASLNLLQLAP
GAHLGRFVIWTEAAFTKLDQVWGSETVASSKVGYTLPSHIISTSDVTRIINSSEIQSAIR
PAGQATQKRTHVLKKNPLKNKQVLLRLNPYAKVFAAEKLGSKKAEKTGTKPAAVFTETLK
HD

Sequence of entity 9 (D), FASTA

>7Z34_9 60S ribosomal protein L5 (chains D)
MAFQKDAKSSAYSSRFQTPFRRRREGKTDYYQRKRLVTQHKAKYNTPKYRLVVRFTNKDI
ICQIISSTITGDVVLAAAYSHELPRYGITHGLTNWAAAYATGLLIARRTLQKLGLDETYK
GVEEVEGEYELTEAVEDGPRPFKVFLDIGLQRTTTGARVFGALKGASDGGLYVPHSENRF
PGWDFETEEIDPELLRSYIFGGHVSQYMEELADDDEERFSELFKGYLADDIDADSLEDIY
TSAHEAIRADPAFKPTEKKFTKEQYAAESKKYRQTKLSKEERAARVAAKIAALAGQQ

Sequence of entity 10 (E), FASTA

>7Z34_10 60S ribosomal protein L6-A (chains E)
MSAQKAPKWYPSEDVAALKKTRKAARPQKLRASLVPGTVLILLAGRFRGKRVVYLKHLED
NTLLISGPFKVNGVPLRRVNARYVIATSTKVSVEGVNVEKFNVEYFAKEKLTKKEKKEAN
LFPEQQNKEIKAERVEDQKVVDKALIAEIKKTPLLKQYLSASFSLKNGDKPHMLKF

Sequence of entity 11 (F), FASTA

>7Z34_11 60S ribosomal protein L7-A (chains F)
MAAEKILTPESQLKKSKAQQKTAEQVAAERAARKAANKEKRAIILERNAAYQKEYETAER
NIIQAKRDAKAAGSYYVEAQHKLVFVVRIKGINKIPPKPRKVLQLLRLTRINSGTFVKVT
KATLELLKLIEPYVAYGYPSYSTIRQLVYKRGFGKINKQRVPLSDNAIIEANLGKYGILS
IDDLIHEIITVGPHFKQANNFLWPFKLSNPSGGWGVPRKFKHFIQGGSFGNREEFINKLV
KSMN

Sequence of entity 12 (G), FASTA

>7Z34_12 60S ribosomal protein L8-A (chains G)
MAPGKKVAPAPFGAKSTKSNKTRNPLTHSTPKNFGIGQAVQPKRNLSRYVKWPEYVRVQR
QKKILSIRLKVPPTIAQFQYTLDRNTAAETFKLFNKYRPETAAEKKERLTKEAAAVAEGK
SKQDASPKPYAVKYGLNHVVALIENKKAKLVLIANDVDPIELVVFLPALCKKMGVPYAIV
KGKARLGTLVNQKTSAVAALTEVRAEDEAALAKLVSTIDANFADKYDEVKKHWGGGILGN
KAQAKMDKRAKNSDSA

Ligands and cofactors

ID	Name	Formula	Copies
MG	Magnesium ion	Mg	1
AGS	Phosphothiophosphoric acid-adenylate ester	C10 H16 N5 O12 P3 S	11

Primary citation

Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1. Prattes, M., Grishkovskaya, I., Hodirnau, V.V. et al. Nat Struct Mol Biol (2022) 29:942-953. DOI 10.1038/s41594-022-00832-5 · PubMed

Other PDB entries of the same protein (UniProt P32794 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7Z11 3.2 Å, Structure of substrate bound DRG1 (AFG2)
7NKU 3.4 Å, diazaborine bound Drg1(AFG2)
7WBB 3.6 Å, Cryo-EM structure of substrate engaged Drg1 hexamer
7WD3 3.8 Å, Cryo-EM structure of Drg1 hexamer treated with ATP and benzo-diazaborine
7YKZ 4.3 Å, Cryo-EM structure of Drg1 hexamer in the planar state treated with ADP/AMPPNP/Diazaborine
7YKL 5.6 Å, Cryo-EM structure of Drg1 hexamer treated with AMPPNP
7YKK 5.9 Å, Cryo-EM structure of Drg1 hexamer treated with ADP
7YKT 5.9 Å, Cryo-EM structure of Drg1 hexamer in helical state treated with…

Browse structure collections

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