7Z8K: Cytoplasmic dynein
Cytoplasmic dynein (A1) bound to BICDR1. Determined by electron microscopy at 4.37 Å resolution. Released 27 Jul 2022.
- Method
- Electron microscopy
- Resolution
- 4.37 Å
- Organisms
- Homo sapiens, Mus musculus, Sus scrofa
- Chains
- 9
- Atoms
- 14,474
- Mol. weight
- 1487.64 kDa
- Released
- 27 Jul 2022
Explore 7Z8K in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
7Z8K contains 111 α-helices and 71 β-strands across 9 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain e: 41 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 211-222 | 12 | |
| α-helix | 229-237 | 9 | |
| α-helix | 239-260 | 22 | |
| α-helix | 271-292 | 22 | |
| α-helix | 295-306 | 12 | |
| α-helix | 310-318 | 9 | |
| α-helix | 322-337 | 16 | |
| α-helix | 341-346 | 6 | |
| α-helix | 350-365 | 16 | |
| α-helix | 366-369 | 4 | |
| α-helix | 374-399 | 26 | |
| α-helix | 406-440 | 35 | |
| α-helix | 456-483 | 28 | |
| α-helix | 514-531 | 18 | |
| α-helix | 540-574 | 35 | |
| α-helix | 578-587 | 10 | |
| α-helix | 590-592 | 3 | |
| α-helix | 597-624 | 28 | |
| α-helix | 631-638 | 8 | |
| α-helix | 643-669 | 27 | |
| α-helix | 673-675 | 3 | |
| α-helix | 677-692 | 16 | |
| α-helix | 696-709 | 14 | |
| β-strand | 718 | 1 | 1 |
| β-strand | 721-723 | 3 | 2 |
| α-helix | 731 | 1 | |
| β-strand | 732-734 | 3 | 2 |
| β-strand | 737 | 1 | 1 |
| α-helix | 742-756 | 15 | |
| α-helix | 762-797 | 36 | |
| α-helix | 799-802 | 4 | |
| α-helix | 806-819 | 14 | |
| α-helix | 829-866 | 38 | |
| α-helix | 871-890 | 20 | |
| α-helix | 896-927 | 32 | |
| α-helix | 930-932 | 3 | |
| α-helix | 933-935 | 3 | |
| α-helix | 956-957 | 2 | |
| β-strand | 958-961 | 4 | 3 |
| β-strand | 962-964 | 3 | 4 |
| β-strand | 969-971 | 3 | 4 |
| α-helix | 975-994 | 20 | |
| β-strand | 997 | 1 | 5 |
| α-helix | 998-999 | 2 | |
| α-helix | 1014-1017 | 4 | |
| β-strand | 1018 | 1 | 5 |
| α-helix | 1022-1024 | 3 | |
| α-helix | 1031-1056 | 26 | |
| α-helix | 1057-1060 | 4 | |
| β-strand | 1099-1102 | 4 | 3 |
| β-strand | 1105-1108 | 4 | 3 |
| α-helix | 1110-1119 | 10 | |
Chain f: 25 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 211-222 | 12 | |
| α-helix | 229-237 | 9 | |
| α-helix | 239-260 | 22 | |
| α-helix | 271-292 | 22 | |
| α-helix | 295-306 | 12 | |
| α-helix | 310-318 | 9 | |
| α-helix | 322-336 | 15 | |
| α-helix | 341-346 | 6 | |
| α-helix | 350-365 | 16 | |
| α-helix | 366-369 | 4 | |
| α-helix | 374-399 | 26 | |
| α-helix | 406-440 | 35 | |
| α-helix | 456-483 | 28 | |
| α-helix | 514-532 | 19 | |
| α-helix | 540-574 | 35 | |
| α-helix | 578-587 | 10 | |
| α-helix | 590-592 | 3 | |
| α-helix | 597-624 | 28 | |
| α-helix | 631-638 | 8 | |
| α-helix | 643-669 | 27 | |
| α-helix | 673-675 | 3 | |
| α-helix | 677-692 | 16 | |
| α-helix | 696-708 | 13 | |
| α-helix | 745-755 | 11 | |
| α-helix | 762-766 | 5 | |
Chain F: 21 helices, 21 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 12-16 | 5 | 17 |
| β-strand | 20-25 | 6 | 17 |
| β-strand | 33-36 | 4 | 17 |
| β-strand | 39-42 | 4 | 18 |
| β-strand | 57-58 | 2 | 18 |
| α-helix | 60-64 | 5 | |
| α-helix | 66-68 | 3 | |
| β-strand | 69-72 | 4 | 18 |
| β-strand | 75-76 | 2 | 19 |
| β-strand | 79-80 | 2 | 19 |
| α-helix | 83-93 | 11 | |
| β-strand | 108-112 | 5 | 17 |
| α-helix | 118-126 | 9 | |
| α-helix | 127-132 | 6 | |
| β-strand | 136-141 | 6 | 17 |
| α-helix | 142-150 | 9 | |
| β-strand | 154-160 | 7 | 20 |
| β-strand | 165-171 | 7 | 20 |
| β-strand | 174-175 | 2 | 20 |
| α-helix | 177-179 | 3 | |
| β-strand | 181-183 | 3 | 20 |
| α-helix | 187-200 | 14 | |
| α-helix | 208-220 | 13 | |
| β-strand | 223 | 1 | 21 |
| α-helix | 228-233 | 6 | |
| β-strand | 240-242 | 3 | 22 |
| β-strand | 248-250 | 3 | 22 |
| α-helix | 254-257 | 4 | |
| α-helix | 260-263 | 4 | |
| α-helix | 275-285 | 11 | |
| α-helix | 288-296 | 9 | |
| β-strand | 298-301 | 4 | 20 |
| α-helix | 303-306 | 4 | |
| β-strand | 308 | 1 | 21 |
| α-helix | 310-321 | 12 | |
| α-helix | 323 | 1 | |
| β-strand | 330-331 | 2 | 20 |
| α-helix | 339-349 | 11 | |
| α-helix | 353-356 | 4 | |
| β-strand | 358-359 | 2 | 17 |
| α-helix | 360-366 | 7 | |
| α-helix | 368-373 | 6 | |
Chain h: 5 helices, 32 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 265-271 | 7 | 8 |
| β-strand | 282-287 | 6 | 9 |
| β-strand | 294-299 | 6 | 9 |
| β-strand | 311-317 | 7 | 9 |
| β-strand | 327-331 | 5 | 9 |
| β-strand | 335-340 | 6 | 10 |
| β-strand | 347-352 | 6 | 10 |
| β-strand | 357-361 | 5 | 10 |
| β-strand | 371 | 1 | 10 |
| β-strand | 384-391 | 8 | 11 |
| β-strand | 396-402 | 7 | 11 |
| β-strand | 406-410 | 5 | 11 |
| β-strand | 411 | 1 | 12 |
| β-strand | 414 | 1 | 12 |
| β-strand | 420-423 | 4 | 11 |
| β-strand | 425 | 1 | 13 |
| β-strand | 431 | 1 | 13 |
| β-strand | 434-438 | 5 | 14 |
| β-strand | 446-451 | 6 | 14 |
| β-strand | 456-460 | 5 | 14 |
| β-strand | 467-468 | 2 | 14 |
| β-strand | 479-484 | 6 | 15 |
| β-strand | 496-501 | 6 | 15 |
| β-strand | 506-510 | 5 | 15 |
| β-strand | 518-520 | 3 | 15 |
| β-strand | 527-532 | 6 | 16 |
| β-strand | 539-544 | 6 | 16 |
| β-strand | 548-553 | 6 | 16 |
| β-strand | 563-566 | 4 | 16 |
| α-helix | 571-572 | 2 | |
| β-strand | 573-578 | 6 | 8 |
| β-strand | 584-589 | 6 | 8 |
| β-strand | 594-599 | 6 | 8 |
| α-helix | 600 | 1 | |
| α-helix | 601-604 | 4 | |
| α-helix | 606-607 | 2 | |
| α-helix | 610-620 | 11 | |
Chain i: 15 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 113-118 | 6 | |
| α-helix | 119-122 | 4 | |
| β-strand | 133-138 | 6 | 6 |
| α-helix | 142-144 | 3 | |
| α-helix | 145-163 | 19 | |
| α-helix | 167-182 | 16 | |
| β-strand | 227-232 | 6 | 6 |
| α-helix | 234-236 | 3 | |
| α-helix | 237-243 | 7 | |
| α-helix | 248-265 | 18 | |
| β-strand | 268-271 | 4 | 6 |
| β-strand | 273 | 1 | 7 |
| β-strand | 278 | 1 | 7 |
| α-helix | 280-292 | 13 | |
| α-helix | 298-300 | 3 | |
| β-strand | 301 | 1 | 6 |
| β-strand | 309-310 | 2 | 6 |
| α-helix | 317-326 | 10 | |
| α-helix | 336-339 | 4 | |
| α-helix | 350-352 | 3 | |
| α-helix | 356-358 | 3 | |
| α-helix | 359-372 | 14 | |
Chains w and W: 1 helix, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 106-268 | 163 | |
Chain x: 1 helix, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 180-312 | 133 | |
Chain X: 1 helix, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 181-314 | 134 | |
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Cytoplasmic dynein 1 heavy chain 1 | e, f | protein | 4646 | Homo sapiens | Q14204 |
| Cytoplasmic dynein 1 light intermediate chain 2 | i | protein | 492 | Homo sapiens | O43237 (AlphaFold model) |
| Cytoplasmic dynein 1 intermediate chain 2 | h | protein | 567 | Homo sapiens | Q13409 (AlphaFold model) |
| BICD family-like cargo adapter 1 | W, X, w, x | protein | 577 | Mus musculus | A0JNT9 (AlphaFold model) |
| ARP1 actin related protein 1 homolog A | F | protein | 376 | Sus scrofa | F2Z5G5 |
Sequence of entity 1 (e, f), FASTA
>7Z8K_1 Cytoplasmic dynein 1 heavy chain 1 (chains e, f)
MSEPGGGGGEDGSAGLEVSAVQNVADVSVLQKHLRKLVPLLLEDGGEAPAALEAALEEKS
ALEQMRKFLSDPQVHTVLVERSTLKEDVGDEGEEEKEFISYNINIDIHYGVKSNSLAFIK
RTPVIDADKPVSSQLRVLTLSEDSPYETLHSFISNAVAPFFKSYIRESGKADRDGDKMAP
SVEKKIAELEMGLLHLQQNIEIPEISLPIHPMITNVAKQCYERGEKPKVTDFGDKVEDPT
FLNQLQSGVNRWIREIQKVTKLDRDPASGTALQEISFWLNLERALYRIQEKRESPEVLLT
LDILKHGKRFHATVSFDTDTGLKQALETVNDYNPLMKDFPLNDLLSATELDKIRQALVAI
FTHLRKIRNTKYPIQRALRLVEAISRDLSSQLLKVLGTRKLMHVAYEEFEKVMVACFEVF
QTWDDEYEKLQVLLRDIVKRKREENLKMVWRINPAHRKLQARLDQMRKFRRQHEQLRAVI
VRVLRPQVTAVAQQNQGEVPEPQDMKVAEVLFDAADANAIEEVNLAYENVKEVDGLDVSK
EGTEAWEAAMKRYDERIDRVETRITARLRDQLGTAKNANEMFRIFSRFNALFVRPHIRGA
IREYQTQLIQRVKDDIESLHDKFKVQYPQSQACKMSHVRDLPPVSGSIIWAKQIDRQLTA
YMKRVEDVLGKGWENHVEGQKLKQDGDSFRMKLNTQEIFDDWARKVQQRNLGVSGRIFTI
ESTRVRGRTGNVLKLKVNFLPEIITLSKEVRNLKWLGFRVPLAIVNKAHQANQLYPFAIS
LIESVRTYERTCEKVEERNTISLLVAGLKKEVQALIAEGIALVWESYKLDPYVQRLAETV
FNFQEKVDDLLIIEEKIDLEVRSLETCMYDHKTFSEILNRVQKAVDDLNLHSYSNLPIWV
NKLDMEIERILGVRLQAGLRAWTQVLLGQAEDKAEVDMDTDAPQVSHKPGGEPKIKNVVH
ELRITNQVIYLNPPIEECRYKLYQEMFAWKMVVLSLPRIQSQRYQVGVHYELTEEEKFYR
NALTRMPDGPVALEESYSAVMGIVSEVEQYVKVWLQYQCLWDMQAENIYNRLGEDLNKWQ
ALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLKYDSWHKEVLSKFGQMLGSNMT
EFHSQISKSRQELEQHSVDTASTSDAVTFITYVQSLKRKIKQFEKQVELYRNGQRLLEKQ
RFQFPPSWLYIDNIEGEWGAFNDIMRRKDSAIQQQVANLQMKIVQEDRAVESRTTDLLTD
WEKTKPVTGNLRPEEALQALTIYEGKFGRLKDDREKCAKAKEALELTDTGLLSGSEERVQ
VALEELQDLKGVWSELSKVWEQIDQMKEQPWVSVQPRKLRQNLDALLNQLKSFPARLRQY
ASYEFVQRLLKGYMKINMLVIELKSEALKDRHWKQLMKRLHVNWVVSELTLGQIWDVDLQ
KNEAIVKDVLLVAQGEMALEEFLKQIREVWNTYELDLVNYQNKCRLIRGWDDLFNKVKEH
INSVSAMKLSPYYKVFEEDALSWEDKLNRIMALFDVWIDVQRRWVYLEGIFTGSADIKHL
LPVETQRFQSISTEFLALMKKVSKSPLVMDVLNIQGVQRSLERLADLLGKIQKALGEYLE
RERSSFPRFYFVGDEDLLEIIGNSKNVAKLQKHFKKMFAGVSSIILNEDNSVVLGISSRE
GEEVMFKTPVSITEHPKINEWLTLVEKEMRVTLAKLLAESVTEVEIFGKATSIDPNTYIT
WIDKYQAQLVVLSAQIAWSENVETALSSMGGGGDAAPLHSVLSNVEVTLNVLADSVLMEQ
PPLRRRKLEHLITELVHQRDVTRSLIKSKIDNAKSFEWLSQMRFYFDPKQTDVLQQLSIQ
MANAKFNYGFEYLGVQDKLVQTPLTDRCYLTMTQALEARLGGSPFGPAGTGKTESVKALG
HQLGRFVLVFNCDETFDFQAMGRIFVGLCQVGAWGCFDEFNRLEERMLSAVSQQVQCIQE
ALREHSNPNYDKTSAPITCELLNKQVKVSPDMAIFITMNPGYAGRSNLPDNLKKLFRSLA
MTKPDRQLIAQVMLYSQGFRTAEVLANKIVPFFKLCDEQLSSQSHYDFGLRALKSVLVSA
GNVKRERIQKIKREKEERGEAVDEGEIAENLPEQEILIQSVCETMVPKLVAEDIPLLFSL
LSDVFPGVQYHRGEMTALREELKKVCQEMYLTYGDGEEVGGMWVEKVLQLYQITQINHGL
MMVGPSGSGKSMAWRVLLKALERLEGVEGVAHIIDPKAISKDHLYGTLDPNTREWTDGLF
THVLRKIIDSVRGELQKRQWIVFDGDVDPEWVENLNSVLDDNKLLTLPNGERLSLPPNVR
IMFEVQDLKYATLATVSRCGMVWFSEDVLSTDMIFNNFLARLRSIPLDEGEDEAQRRRKG
KEDEGEEAASPMLQIQRDAATIMQPYFTSNGLVTKALEHAFQLEHIMDLTRLRCLGSLFS
MLHQACRNVAQYNANHPDFPMQIEQLERYIQRYLVYAILWSLSGDSRLKMRAELGEYIRR
ITTVPLPTAPNIPIIDYEVSISGEWSPWQAKVPQIEVETHKVAAPDVVVPTLDTVRHEAL
LYTWLAEHKPLVLCGPPGSGKTMTLFSALRALPDMEVVGLNFSSATTPELLLKTFDHYCE
YRRTPNGVVLAPVQLGKWLVLFCDEINLPDMDKYGTQRVISFIRQMVEHGGFYRTSDQTW
VKLERIQFVGACNPPTDPGRKPLSHRFLRHVPVVYVDYPGPASLTQIYGTFNRAMLRLIP
SLRTYAEPLTAAMVEFYTMSQERFTQDTQPHYIYSPREMTRWVRGIFEALRPLETLPVEG
LIRIWAHEALRLFQDRLVEDEERRWTDENIDTVALKHFPNIDREKAMSRPILYSNWLSKD
YIPVDQEELRDYVKARLKVFYEEELDVPLVLFNEVLDHVLRIDRIFRQPQGHLLLIGVSG
AGKTTLSRFVAWMNGLSVYQIKVHRKYTGEDFDEDLRTVLRRSGCKNEKIAFIMDESNVL
DSGFLERMNTLLANGEVPGLFEGDEYATLMTQCKEGAQKEGLMLDSHEELYKWFTSQVIR
NLHVVFTMNPSSEGLKDRAATSPALFNRCVLNWFGDWSTEALYQVGKEFTSKMDLEKPNY
IVPDYMPVVYDKLPQPPSHREAIVNSCVFVHQTLHQANARLAKRGGRTMAITPRHYLDFI
NHYANLFHEKRSELEEQQMHLNVGLRKIKETVDQVEELRRDLRIKSQELEVKNAAANDKL
KKMVKDQQEAEKKKVMSQEIQEQLHKQQEVIADKQMSVKEDLDKVEPAVIEAQNAVKSIK
KQHLVEVRSMANPPAAVKLALESICLLLGESTTDWKQIRSIIMRENFIPTIVNFSAEEIS
DAIREKMKKNYMSNPSYNYEIVNRASLACGPMVKWAIAQLNYADMLKRVEPLRNELQKLE
DDAKDNQQKANEVEQMIRDLEASIARYKEEYAVLISEAQAIKADLAAVEAKVNRSTALLK
SLSAERERWEKTSETFKNQMSTIAGDCLLSAAFIAYAGYFDQQMRQNLFTTWSHHLQQAN
IQFRTDIARTEYLSNADERLRWQASSLPADDLCTENAIMLKRFNRYPLIIDPSGQATEFI
MNEYKDRKITRTSFLDDAFRKNLESALRFGNPLLVQDVESYDPVLNPVLNREVRRTGGRV
LITLGDQDIDLSPSFVIFLSTRDPTVEFPPDLCSRVTFVNFTVTRSSLQSQCLNEVLKAE
RPDVDEKRSDLLKLQGEFQLRLRQLEKSLLQALNEVKGRILDDDTIITTLENLKREAAEV
TRKVEETDIVMQEVETVSQQYLPLSTACSSIYFTMESLKQIHFLYQYSLQFFLDIYHNVL
YENPNLKGVTDHTQRLSIITKDLFQVAFNRVARGMLHQDHITFAMLLARIKLKGTVGEPT
YDAEFQHFLRGNEIVLSAGSTPRIQGLTVEQAEAVVRLSCLPAFKDLIAKVQADEQFGIW
LDSSSPEQTVPYLWSEETPATPIGQAIHRLLLIQAFRPDRLLAMAHMFVSTNLGESFMSI
MEQPLDLTHIVGTEVKPNTPVLMCSVPGYDASGHVEDLAAEQNTQITSIAIGSAEGFNQA
DKAINTAVKSGRWVMLKNVHLAPGWLMQLEKKLHSLQPHACFRLFLTMEINPKVPVNLLR
AGRIFVFEPPPGVKANMLRTFSSIPVSRICKSPNERARLYFLLAWFHAIIQERLRYAPLG
WSKKYEFGESDLRSACDTVDTWLDDTAKGRQNISPDKIPWSALKTLMAQSIYGGRVDNEF
DQRLLNTFLERLFTTRSFDSEFKLACKVDGHKDIQMPDGIRREEFVQWVELLPDTQTPSW
LGLPNNAERVLLTTQGVDMISKMLKMQMLEDEDDLAYAETEKKTRTDSTSDGRPAWMRTL
HTTASNWLHLIPQTLSHLKRTVENIKDPLFRFFEREVKMGAKLLQDVRQDLADVVQVCEG
KKKQTNYLRTLINELVKGILPRSWSHYTVPAGMTVIQWVSDFSERIKQLQNISLAAASGG
AKELKNIHVCLGGLFVPEAYITATRQYVAQANSWSLEELCLEVNVTTSQGATLDACSFGV
TGLKLQGATCNNNKLSLSNAISTALPLTQLRWVKQTNTEKKASVVTLPVYLNFTRADLIF
TVDFEIATKEDPRSFYERGVAVLCTE
Sequence of entity 2 (i), FASTA
>7Z8K_2 Cytoplasmic dynein 1 light intermediate chain 2 (chains i)
MAPVGVEKKLLLGPNGPAVAAAGDLTSEEEEGQSLWSSILSEVSTRARSKLPSGKNILVF
GEDGSGKTTLMTKLQGAEHGKKGRGLEYLYLSVHDEDRDDHTRCNVWILDGDLYHKGLLK
FAVSAESLPETLVIFVADMSRPWTVMESLQKWASVLREHIDKMKIPPEKMRELERKFVKD
FQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVL
EKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPA
LVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQ
VFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGTSVKKPDPNIK
NNAASEGVLASFFNSLLSKKTGSPGSPGAGGVQSTAKKSGQKTVLSNVQEELDRMTRKPD
SMVTNSSTENEA
Sequence of entity 3 (h), FASTA
>7Z8K_3 Cytoplasmic dynein 1 intermediate chain 2 (chains h)
ESPIVFSEYWVPPPMSPSSKSVSTPSEAGSQDSGDGAVGSRTLHWDTDPSVLQLHSDSDL
GRGPIKLGMAKITQVDFPPREIVTYTKETQTPVMAQPKEDEEEDDDVVAPKPPIEPEEEK
TLKKDEENDSKAPPHELTEEEKQQILHSEEFLSFFDHSTRIVERALSEQINIFFDYSGRD
LEDKEGEIQAGAKLSLNRQFFDERWSKHRVVSCLDWSSQYPELLVASYNNNEDAPHEPDG
VALVWNMKYKKTTPEYVFHCQSAVMSATFAKFHPNLVVGGTYSGQIVLWDNRSNKRTPVQ
RTPLSAAAHTHPVYCVNVVGTQNAHNLISISTDGKICSWSLDMLSHPQDSMELVHKQSKA
VAVTSMSFPVGDVNNFVVGSEEGSVYTACRHGSKAGISEMFEGHQGPITGIHCHAAVGAV
DFSHLFVTSSFDWTVKLWTTKNNKPLYSFEDNADYVYDVMWSPTHPALFACVDGMGRLDL
WNLNNDTEVPTASISVEGNPALNRVRWTHSGREIAVGDSEGQIVIYDVGEQIAVPRNDEW
ARFGRTLAEINANRADAEEEAATRIPA
Sequence of entity 4 (W, X, w, x), FASTA
>7Z8K_4 BICD family-like cargo adapter 1 (chains W, X, w, x)
MSAFCLGLAGRASAPAEPDSACCMELPAGAGDAVRSPATAAALVSFPGGPGELELALEEE
LALLAAGERSSEPGEHPQAEPESPVEGHGPPLPPPPTQDPELLSVIRQKEKDLVLAARLG
KALLERNQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFENREGEWEGRVSELETDVKQL
QDELERQQLHLREADREKTRAVQELSEQNQRLLDQLSRASEVERQLSMQVHALKEDFREK
NSSTNQHIIRLESLQAEIKMLSDRKRELEHRLSATLEENDLLQGTVEELQDRVLILERQG
HDKDLQLHQSQLELQEVRLSYRQLQGKVEELTEERSLQSSAATSTSLLSEIEQSMEAEEL
EQEREQLRLQLWEAYCQVRYLCSHLRGNDSADSAVSTDSSMDESSETSSAKDVPAGSLRT
ALNDLKRLIQSIVDGVEPTVTLLSVEMTALKEERDRLRVTSEDKEPKEQLQKAIRDRDEA
IAKKNAVELELAKCKMDMMSLNSQLLDAIQQKLNLSQQLEAWQDDMHRVIDRQLMDTHLK
EQSRPAAAAFPRGHGVGRGQEPSTADGKRLFSFFRKI
Sequence of entity 5 (F), FASTA
>7Z8K_5 ARP1 actin related protein 1 homolog A (chains F)
MESYDVIANQPVVIDNGSGVIKAGFAGDQIPKYCFPNYVGRPKHVRVMAGALEGDIFIGP
KAEEHRGLLSIRYPMEHGIVKDWNDMERIWQYVYSKDQLQTFSEEHPVLLTEAPLNPRKN
RERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPIYEGFAMPHSI
MRIDIAGRDVSRFLRLYLRKEGYDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQ
YYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRRTLFSNIVL
SGGSTLFKGFGDRLLSEVKKLAPKDVKIRISAPQERLYSTWIGGSILASLDTFKKMWVSK
KEYEEDGARSIHRKTF
Primary citation
Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Chaaban, S., Carter, A.P. Nature (2022) 610:212-216. DOI 10.1038/s41586-022-05186-y · PubMed
Other PDB entries of the same protein (UniProt Q14204), best resolution first:
- 5OWO 1.79 Å, Human cytoplasmic Dynein N-Terminus dimerization domain at 1.8 Angstrom resolution
- 9BLZ 2.2 Å, State-1(phi motor) of full-length human dynein-1 in 5mM ATP
- 9BMR 2.6 Å, State-1 of motor domain from full-length human phi dynein-1 in 5 mM ADP
- 9DH5 2.6 Å, State-1 of the motor domain from full-length human dynein-1 in 5mM AMPPNP with 5mM Mg2+
- 9E0X 2.7 Å, Cryo-EM structure of Phi dynein
- 9E10 2.71 Å, Dimeric motor domains from phi dynein-1 under Lis1 condition
- 9BM0 2.8 Å, State-2 of motor domain from full-length human dynein-1 in 5mM ATP
- 9BMF 2.8 Å, State-1(phi motor) of full-length human dynein-1 in 5mM ATPVi
- 9BMH 2.8 Å, State-4 of motor domain from full-length human dynein-1 in 5mM ATPVi
- 9BN3 2.8 Å, The alpha registry-locked dynein motor domain mutant in 5mM ATP condition, class1
- 9BM2 2.82 Å, State-4 of motor domain from full-length human dynein-1 in 5 mM ATP
- 9BMG 2.86 Å, State-2 of full-length human dynein-1 in 5mM ATPVi
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MolViewer shows 7Z8K directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.