8BG9: Amyloid-beta protein 40

Murine amyloid-beta filaments with the Arctic mutation (E22G) from APP(NL-G-F) mouse brains | ABeta. Determined by electron microscopy at 3.5 Å resolution. Released 18 Jan 2023.

Method
Electron microscopy
Resolution
3.5 Å
Organism
Mus musculus
Chains
2
Atoms
564
Mol. weight
8.02 kDa
Released
18 Jan 2023

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Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
Amyloid-beta protein 40A, Bprotein37Mus musculusP12023 (AlphaFold model)
Sequence of entity 1 (A, B), FASTA
>8BG9_1 Amyloid-beta protein 40 (chains A, B)
DAEFRHDSGYEVHHQKLVFFAGDVGSNKGAIIGLMVG

Primary citation

Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains. Yang, Y., Zhang, W., Murzin, A.G. et al. Acta Neuropathol (2023) 145:325-333. DOI 10.1007/s00401-022-02533-1 · PubMed

Other PDB entries of the same protein (UniProt P12023 (AlphaFold model), which also has an AlphaFold model), best resolution first:

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