8BHV: DNA-PK XLF mediated dimer
DNA-PK XLF mediated dimer bound to PAXX. Determined by electron microscopy at 4.51 Å resolution. Released 7 Jun 2023.
- Method
- Electron microscopy
- Resolution
- 4.51 Å
- Organism
- Homo sapiens
- Chains
- 20
- Atoms
- 91,357
- Mol. weight
- 1748.24 kDa
- Released
- 7 Jun 2023
Explore 8BHV in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8BHV contains 588 α-helices and 224 β-strands across 16 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain a: 20 helices, 27 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 35-43 | 9 | 49 |
| α-helix | 59-77 | 19 | |
| β-strand | 82-88 | 7 | 49 |
| β-strand | 102-109 | 8 | 49 |
| α-helix | 113-120 | 8 | |
| α-helix | 127-134 | 8 | |
| α-helix | 143-155 | 13 | |
| β-strand | 161-169 | 9 | 49 |
| α-helix | 174-178 | 5 | |
| α-helix | 180-195 | 16 | |
| β-strand | 198-202 | 5 | 49 |
| α-helix | 239-243 | 5 | |
| α-helix | 251-253 | 3 | |
| β-strand | 257-262 | 6 | 50 |
| β-strand | 268-274 | 7 | 50 |
| β-strand | 277 | 1 | 51 |
| α-helix | 282-285 | 4 | |
| β-strand | 286-289 | 4 | 52 |
| β-strand | 295 | 1 | 52 |
| β-strand | 297-304 | 8 | 53 |
| β-strand | 310 | 1 | 53 |
| α-helix | 313-315 | 3 | |
| β-strand | 316-317 | 2 | 54 |
| β-strand | 318-322 | 5 | 55 |
| β-strand | 325-329 | 5 | 55 |
| α-helix | 332-336 | 5 | |
| β-strand | 344-352 | 9 | 50 |
| α-helix | 353-355 | 3 | |
| β-strand | 366-371 | 6 | 50 |
| β-strand | 375-376 | 2 | 56 |
| α-helix | 378-392 | 15 | |
| β-strand | 394-401 | 8 | 50 |
| β-strand | 409-416 | 8 | 50 |
| α-helix | 417-418 | 2 | |
| β-strand | 419-420 | 2 | 57 |
| β-strand | 426-428 | 3 | 57 |
| β-strand | 431-437 | 7 | 50 |
| α-helix | 440-442 | 3 | |
| β-strand | 443 | 1 | 58 |
| β-strand | 445 | 1 | 59 |
| α-helix | 456-468 | 13 | |
| β-strand | 470 | 1 | 58 |
| β-strand | 471 | 1 | 60 |
| α-helix | 481-495 | 15 | |
| α-helix | 500-504 | 5 | |
| α-helix | 511-518 | 8 | |
| α-helix | 521-529 | 9 | |
Chain A: 213 helices, 23 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 11-22 | 12 | |
| α-helix | 29-46 | 18 | |
| α-helix | 52-69 | 18 | |
| α-helix | 76-93 | 18 | |
| α-helix | 98-100 | 3 | |
| α-helix | 101-113 | 13 | |
| α-helix | 114-118 | 5 | |
| α-helix | 125-140 | 16 | |
| α-helix | 149-160 | 12 | |
| α-helix | 169-172 | 4 | |
| α-helix | 173-178 | 6 | |
| α-helix | 187-208 | 22 | |
| α-helix | 217-231 | 15 | |
| α-helix | 232-234 | 3 | |
| α-helix | 241-254 | 14 | |
| α-helix | 267-277 | 11 | |
| α-helix | 280-282 | 3 | |
| α-helix | 290-300 | 11 | |
| α-helix | 306-328 | 23 | |
| α-helix | 334-336 | 3 | |
| α-helix | 337-341 | 5 | |
| α-helix | 342-348 | 7 | |
| α-helix | 357-375 | 19 | |
| α-helix | 378-397 | 20 | |
| α-helix | 410-423 | 14 | |
| α-helix | 431-444 | 14 | |
| α-helix | 451-468 | 18 | |
| α-helix | 472-491 | 20 | |
| α-helix | 524-526 | 3 | |
| α-helix | 527-535 | 9 | |
| α-helix | 538-546 | 9 | |
| α-helix | 560-578 | 19 | |
| β-strand | 583-584 | 2 | 1 |
| β-strand | 613-614 | 2 | 1 |
| α-helix | 617-633 | 17 | |
| α-helix | 634-636 | 3 | |
| α-helix | 639-659 | 21 | |
| α-helix | 664-680 | 17 | |
| α-helix | 698-717 | 20 | |
| α-helix | 718-720 | 3 | |
| α-helix | 726-734 | 9 | |
| α-helix | 738-741 | 4 | |
| α-helix | 745-758 | 14 | |
| α-helix | 763-779 | 17 | |
| α-helix | 782-795 | 14 | |
| α-helix | 835-839 | 5 | |
| α-helix | 841-844 | 4 | |
| α-helix | 848-862 | 15 | |
| α-helix | 864-867 | 4 | |
| α-helix | 868-870 | 3 | |
| β-strand | 893-895 | 3 | 2 |
| β-strand | 904-906 | 3 | 2 |
| α-helix | 907-910 | 4 | |
| α-helix | 911-919 | 9 | |
| α-helix | 924-945 | 22 | |
| α-helix | 960-973 | 14 | |
| α-helix | 978-994 | 17 | |
| α-helix | 1005-1017 | 13 | |
| α-helix | 1023-1043 | 21 | |
| α-helix | 1046-1051 | 6 | |
| α-helix | 1056-1068 | 13 | |
| α-helix | 1072-1089 | 18 | |
| α-helix | 1093-1098 | 6 | |
| α-helix | 1101-1116 | 16 | |
| α-helix | 1123-1140 | 18 | |
| α-helix | 1143-1146 | 4 | |
| β-strand | 1149 | 1 | 3 |
| α-helix | 1153-1154 | 2 | |
| β-strand | 1163 | 1 | 3 |
| α-helix | 1165-1174 | 10 | |
| α-helix | 1181-1194 | 14 | |
| α-helix | 1206-1214 | 9 | |
| α-helix | 1218-1221 | 4 | |
| β-strand | 1227 | 1 | 4 |
| β-strand | 1230 | 1 | 4 |
| α-helix | 1232-1236 | 5 | |
| α-helix | 1250-1272 | 23 | |
| α-helix | 1278-1281 | 4 | |
| α-helix | 1288-1299 | 12 | |
| α-helix | 1323-1325 | 3 | |
| α-helix | 1327-1350 | 24 | |
| α-helix | 1354-1356 | 3 | |
| α-helix | 1357-1361 | 5 | |
| α-helix | 1368-1377 | 10 | |
| α-helix | 1390-1408 | 19 | |
| α-helix | 1412-1422 | 11 | |
| α-helix | 1428-1431 | 4 | |
| α-helix | 1443-1460 | 18 | |
| α-helix | 1477-1489 | 13 | |
| α-helix | 1505-1519 | 15 | |
| α-helix | 1524-1532 | 9 | |
| α-helix | 1555-1573 | 19 | |
| α-helix | 1577-1585 | 9 | |
| α-helix | 1591-1606 | 16 | |
| α-helix | 1613-1624 | 12 | |
| α-helix | 1626-1628 | 3 | |
| α-helix | 1639-1655 | 17 | |
| α-helix | 1668-1680 | 13 | |
| α-helix | 1686-1694 | 9 | |
| α-helix | 1696-1698 | 3 | |
| α-helix | 1708-1721 | 14 | |
| α-helix | 1730 | 1 | |
| α-helix | 1734-1753 | 20 | |
| α-helix | 1756-1766 | 11 | |
| α-helix | 1775-1786 | 12 | |
| α-helix | 1791-1803 | 13 | |
| α-helix | 1816-1819 | 4 | |
| α-helix | 1820-1825 | 6 | |
| α-helix | 1826-1830 | 5 | |
| α-helix | 1833-1842 | 10 | |
| α-helix | 1844-1850 | 7 | |
| α-helix | 1863-1883 | 21 | |
| α-helix | 1912-1923 | 12 | |
| α-helix | 1936-1954 | 19 | |
| α-helix | 2035-2047 | 13 | |
| α-helix | 2095-2106 | 12 | |
| α-helix | 2126-2134 | 9 | |
| α-helix | 2140-2152 | 13 | |
| α-helix | 2158-2160 | 3 | |
| α-helix | 2161-2172 | 12 | |
| α-helix | 2182-2194 | 13 | |
| α-helix | 2206-2222 | 17 | |
| α-helix | 2230-2243 | 14 | |
| α-helix | 2255-2261 | 7 | |
| α-helix | 2271-2282 | 12 | |
| α-helix | 2298-2308 | 11 | |
| α-helix | 2314-2328 | 15 | |
| α-helix | 2339-2350 | 12 | |
| α-helix | 2358-2370 | 13 | |
| α-helix | 2375-2378 | 4 | |
| α-helix | 2379-2385 | 7 | |
| α-helix | 2386-2388 | 3 | |
| α-helix | 2392-2403 | 12 | |
| α-helix | 2412-2417 | 6 | |
| α-helix | 2420-2425 | 6 | |
| α-helix | 2429-2442 | 14 | |
| α-helix | 2448-2458 | 11 | |
| α-helix | 2459-2461 | 3 | |
| α-helix | 2467-2483 | 17 | |
| α-helix | 2493-2509 | 17 | |
| α-helix | 2515-2526 | 12 | |
| α-helix | 2535-2542 | 8 | |
| α-helix | 2554-2564 | 11 | |
| β-strand | 2575 | 1 | 5 |
| β-strand | 2587-2589 | 3 | 6 |
| α-helix | 2724-2730 | 7 | |
| α-helix | 2731-2734 | 4 | |
| α-helix | 2738-2764 | 27 | |
| α-helix | 2766-2769 | 4 | |
| β-strand | 2775-2777 | 3 | 6 |
| β-strand | 2786 | 1 | 5 |
| α-helix | 2787-2800 | 14 | |
| α-helix | 2802-2820 | 19 | |
| α-helix | 2821-2823 | 3 | |
| α-helix | 2826-2846 | 21 | |
| α-helix | 2852-2864 | 13 | |
| α-helix | 2866-2870 | 5 | |
| α-helix | 2873-2882 | 10 | |
| α-helix | 2886-2900 | 15 | |
| α-helix | 2920-2932 | 13 | |
| α-helix | 2937-2942 | 6 | |
| α-helix | 2943-2947 | 5 | |
| α-helix | 2951-2961 | 11 | |
| α-helix | 2966-2976 | 11 | |
| α-helix | 2985-2987 | 3 | |
| α-helix | 2988-3004 | 17 | |
| α-helix | 3008-3015 | 8 | |
| α-helix | 3035-3054 | 20 | |
| α-helix | 3060-3069 | 10 | |
| α-helix | 3072-3092 | 21 | |
| α-helix | 3096-3116 | 21 | |
| α-helix | 3122-3143 | 22 | |
| α-helix | 3150-3152 | 3 | |
| α-helix | 3158-3161 | 4 | |
| α-helix | 3163-3166 | 4 | |
| α-helix | 3176-3196 | 21 | |
| α-helix | 3227-3248 | 22 | |
| α-helix | 3256-3266 | 11 | |
| α-helix | 3270-3287 | 18 | |
| α-helix | 3292-3298 | 7 | |
| α-helix | 3301-3307 | 7 | |
| α-helix | 3308-3310 | 3 | |
| α-helix | 3320-3343 | 24 | |
| α-helix | 3348-3351 | 4 | |
| α-helix | 3355-3363 | 9 | |
| α-helix | 3370-3393 | 24 | |
| α-helix | 3408-3427 | 20 | |
| α-helix | 3442-3455 | 14 | |
| α-helix | 3459-3463 | 5 | |
| α-helix | 3465-3474 | 10 | |
| α-helix | 3476-3483 | 8 | |
| α-helix | 3499-3506 | 8 | |
| α-helix | 3512-3524 | 13 | |
| α-helix | 3530-3537 | 8 | |
| α-helix | 3548-3561 | 14 | |
| α-helix | 3566-3578 | 13 | |
| α-helix | 3581-3596 | 16 | |
| α-helix | 3606-3613 | 8 | |
| α-helix | 3614-3618 | 5 | |
| α-helix | 3628-3643 | 16 | |
| α-helix | 3658-3668 | 11 | |
| α-helix | 3685-3687 | 3 | |
| α-helix | 3697-3698 | 2 | |
| β-strand | 3699-3700 | 2 | 7 |
| α-helix | 3701 | 1 | |
| β-strand | 3718-3719 | 2 | 7 |
| β-strand | 3727-3728 | 2 | 8 |
| β-strand | 3736-3741 | 6 | 8 |
| β-strand | 3742 | 1 | 7 |
| β-strand | 3747-3753 | 7 | 8 |
| α-helix | 3759-3777 | 19 | |
| α-helix | 3779-3784 | 6 | |
| β-strand | 3793-3797 | 5 | 8 |
| β-strand | 3800-3804 | 5 | 8 |
| β-strand | 3809-3811 | 3 | 9 |
| α-helix | 3812-3818 | 7 | |
| α-helix | 3822-3830 | 9 | |
| α-helix | 3834-3839 | 6 | |
| α-helix | 3854-3861 | 8 | |
| α-helix | 3864-3877 | 14 | |
| α-helix | 3882-3890 | 9 | |
| α-helix | 3894-3917 | 24 | |
| α-helix | 3925-3927 | 3 | |
| β-strand | 3928-3931 | 4 | 9 |
| β-strand | 3937-3939 | 3 | 9 |
| α-helix | 3948-3951 | 4 | |
| α-helix | 3965-3968 | 4 | |
| α-helix | 3979-3990 | 12 | |
| α-helix | 3994-3998 | 5 | |
| α-helix | 4040-4051 | 12 | |
| α-helix | 4056-4068 | 13 | |
| α-helix | 4074-4082 | 9 | |
| α-helix | 4086-4089 | 4 | |
| α-helix | 4090-4092 | 3 | |
| α-helix | 4100-4109 | 10 | |
| α-helix | 4113-4118 | 6 | |
Chain b: 31 helices, 25 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 9-15 | 7 | 61 |
| α-helix | 18-21 | 4 | |
| α-helix | 30-47 | 18 | |
| β-strand | 54-59 | 6 | 61 |
| β-strand | 65 | 1 | 61 |
| β-strand | 77-84 | 8 | 61 |
| α-helix | 88-92 | 5 | |
| α-helix | 93-97 | 5 | |
| α-helix | 107-121 | 15 | |
| β-strand | 130-135 | 6 | 61 |
| α-helix | 147-157 | 11 | |
| β-strand | 160-165 | 6 | 61 |
| α-helix | 168-169 | 2 | |
| α-helix | 199-216 | 18 | |
| α-helix | 218-221 | 4 | |
| β-strand | 225-226 | 2 | 61 |
| α-helix | 227-234 | 8 | |
| α-helix | 237-240 | 4 | |
| β-strand | 243 | 1 | 59 |
| β-strand | 247-253 | 7 | 58 |
| β-strand | 257-268 | 12 | 58 |
| β-strand | 279-280 | 2 | 54 |
| α-helix | 286-288 | 3 | |
| β-strand | 289-296 | 8 | 53 |
| β-strand | 305 | 1 | 53 |
| α-helix | 307-309 | 3 | |
| β-strand | 310-316 | 7 | 52 |
| β-strand | 319-322 | 4 | 52 |
| α-helix | 325-330 | 6 | |
| β-strand | 340-347 | 8 | 58 |
| α-helix | 348-350 | 3 | |
| α-helix | 353-355 | 3 | |
| β-strand | 357-366 | 10 | 58 |
| α-helix | 371-387 | 17 | |
| β-strand | 389-395 | 7 | 58 |
| α-helix | 402-403 | 2 | |
| β-strand | 404-412 | 9 | 58 |
| β-strand | 417-423 | 7 | 58 |
| α-helix | 427-429 | 3 | |
| β-strand | 430 | 1 | 51 |
| α-helix | 448-461 | 14 | |
| β-strand | 462 | 1 | 50 |
| β-strand | 466-467 | 2 | 62 |
| β-strand | 472-473 | 2 | 62 |
| α-helix | 485-499 | 15 | |
| α-helix | 504-506 | 3 | |
| α-helix | 510-516 | 7 | |
| α-helix | 518-519 | 2 | |
| α-helix | 520-536 | 17 | |
| β-strand | 540-541 | 2 | 56 |
| α-helix | 596-603 | 8 | |
| α-helix | 617-622 | 6 | |
| α-helix | 629-648 | 20 | |
| α-helix | 652-668 | 17 | |
| α-helix | 675-685 | 11 | |
| α-helix | 695-701 | 7 | |
Chain c: 1 helix, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| α-helix | 191-192 | 2 | |
| β-strand | 201 | 1 | 60 |
Chain F: 217 helices, 26 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-22 | 11 | |
| α-helix | 28-46 | 19 | |
| α-helix | 52-66 | 15 | |
| α-helix | 67-71 | 5 | |
| α-helix | 76-94 | 19 | |
| α-helix | 98-100 | 3 | |
| α-helix | 101-116 | 16 | |
| α-helix | 118-120 | 3 | |
| α-helix | 125-140 | 16 | |
| α-helix | 150-161 | 12 | |
| α-helix | 170-172 | 3 | |
| α-helix | 173-178 | 6 | |
| α-helix | 187-208 | 22 | |
| α-helix | 210-212 | 3 | |
| α-helix | 217-232 | 16 | |
| α-helix | 241-251 | 11 | |
| α-helix | 266-277 | 12 | |
| α-helix | 280-282 | 3 | |
| α-helix | 290-300 | 11 | |
| α-helix | 306-328 | 23 | |
| α-helix | 333-339 | 7 | |
| α-helix | 342-348 | 7 | |
| α-helix | 358-375 | 18 | |
| α-helix | 378-394 | 17 | |
| α-helix | 410-423 | 14 | |
| α-helix | 431-444 | 14 | |
| α-helix | 451-468 | 18 | |
| α-helix | 472-491 | 20 | |
| α-helix | 494-495 | 2 | |
| α-helix | 524-527 | 4 | |
| α-helix | 528-535 | 8 | |
| α-helix | 538-546 | 9 | |
| α-helix | 560-578 | 19 | |
| β-strand | 584 | 1 | 10 |
| β-strand | 613 | 1 | 10 |
| α-helix | 617-633 | 17 | |
| α-helix | 634-636 | 3 | |
| α-helix | 639-642 | 4 | |
| α-helix | 645-659 | 15 | |
| α-helix | 664-679 | 16 | |
| α-helix | 698-718 | 21 | |
| α-helix | 726-734 | 9 | |
| α-helix | 740-742 | 3 | |
| α-helix | 745-759 | 15 | |
| α-helix | 763-779 | 17 | |
| α-helix | 782-792 | 11 | |
| α-helix | 794-801 | 8 | |
| α-helix | 835-838 | 4 | |
| α-helix | 849-862 | 14 | |
| α-helix | 864-867 | 4 | |
| α-helix | 868-870 | 3 | |
| β-strand | 895 | 1 | 11 |
| α-helix | 896-897 | 2 | |
| β-strand | 904 | 1 | 11 |
| α-helix | 907-909 | 3 | |
| α-helix | 910-919 | 10 | |
| α-helix | 924-944 | 21 | |
| α-helix | 959-973 | 15 | |
| α-helix | 978-994 | 17 | |
| α-helix | 1005-1014 | 10 | |
| α-helix | 1023-1043 | 21 | |
| α-helix | 1046-1051 | 6 | |
| α-helix | 1056-1068 | 13 | |
| α-helix | 1072-1091 | 20 | |
| α-helix | 1094-1098 | 5 | |
| α-helix | 1101-1116 | 16 | |
| α-helix | 1123-1140 | 18 | |
| α-helix | 1143-1146 | 4 | |
| β-strand | 1149 | 1 | 12 |
| α-helix | 1152-1154 | 3 | |
| β-strand | 1163 | 1 | 12 |
| α-helix | 1165-1175 | 11 | |
| α-helix | 1181-1194 | 14 | |
| α-helix | 1206-1214 | 9 | |
| α-helix | 1218-1222 | 5 | |
| α-helix | 1233-1237 | 5 | |
| α-helix | 1250-1273 | 24 | |
| α-helix | 1278-1281 | 4 | |
| α-helix | 1288-1300 | 13 | |
| α-helix | 1327-1350 | 24 | |
| α-helix | 1354-1356 | 3 | |
| α-helix | 1358-1362 | 5 | |
| α-helix | 1368-1377 | 10 | |
| α-helix | 1379-1381 | 3 | |
| α-helix | 1390-1408 | 19 | |
| α-helix | 1412-1422 | 11 | |
| α-helix | 1429-1432 | 4 | |
| α-helix | 1443-1460 | 18 | |
| α-helix | 1477-1489 | 13 | |
| α-helix | 1505-1520 | 16 | |
| α-helix | 1524-1532 | 9 | |
| β-strand | 1537 | 1 | 13 |
| β-strand | 1554 | 1 | 13 |
| α-helix | 1555-1573 | 19 | |
| α-helix | 1577-1585 | 9 | |
| α-helix | 1591-1606 | 16 | |
| α-helix | 1613-1625 | 13 | |
| α-helix | 1626-1628 | 3 | |
| α-helix | 1639-1655 | 17 | |
| α-helix | 1668-1680 | 13 | |
| α-helix | 1686-1693 | 8 | |
| α-helix | 1696-1698 | 3 | |
| α-helix | 1708-1719 | 12 | |
| α-helix | 1734-1753 | 20 | |
| α-helix | 1756-1766 | 11 | |
| α-helix | 1775-1787 | 13 | |
| α-helix | 1791-1805 | 15 | |
| α-helix | 1816-1821 | 6 | |
| α-helix | 1824-1830 | 7 | |
| α-helix | 1833-1842 | 10 | |
| α-helix | 1844-1851 | 8 | |
| α-helix | 1864-1883 | 20 | |
| α-helix | 1911-1923 | 13 | |
| α-helix | 1935-1951 | 17 | |
| α-helix | 2035-2047 | 13 | |
| α-helix | 2095-2107 | 13 | |
| α-helix | 2126-2134 | 9 | |
| α-helix | 2140-2152 | 13 | |
| α-helix | 2158-2160 | 3 | |
| α-helix | 2161-2172 | 12 | |
| α-helix | 2182-2195 | 14 | |
| α-helix | 2206-2222 | 17 | |
| α-helix | 2229-2245 | 17 | |
| α-helix | 2254-2261 | 8 | |
| α-helix | 2271-2282 | 12 | |
| α-helix | 2298-2308 | 11 | |
| α-helix | 2313-2328 | 16 | |
| α-helix | 2330-2333 | 4 | |
| α-helix | 2339-2350 | 12 | |
| α-helix | 2358-2368 | 11 | |
| α-helix | 2372-2375 | 4 | |
| α-helix | 2376-2378 | 3 | |
| α-helix | 2379-2385 | 7 | |
| α-helix | 2386-2388 | 3 | |
| α-helix | 2392-2403 | 12 | |
| α-helix | 2412-2417 | 6 | |
| α-helix | 2420-2425 | 6 | |
| α-helix | 2429-2442 | 14 | |
| α-helix | 2443-2445 | 3 | |
| α-helix | 2448-2455 | 8 | |
| α-helix | 2459-2461 | 3 | |
| α-helix | 2467-2484 | 18 | |
| α-helix | 2493-2509 | 17 | |
| α-helix | 2515-2526 | 12 | |
| α-helix | 2535-2544 | 10 | |
| α-helix | 2554-2563 | 10 | |
| β-strand | 2575 | 1 | 14 |
| β-strand | 2587-2588 | 2 | 15 |
| α-helix | 2724-2730 | 7 | |
| α-helix | 2738-2763 | 26 | |
| α-helix | 2766-2770 | 5 | |
| β-strand | 2776-2777 | 2 | 15 |
| β-strand | 2786 | 1 | 14 |
| α-helix | 2787-2800 | 14 | |
| α-helix | 2802-2820 | 19 | |
| α-helix | 2821-2823 | 3 | |
| α-helix | 2826-2846 | 21 | |
| α-helix | 2852-2864 | 13 | |
| α-helix | 2866-2869 | 4 | |
| α-helix | 2873-2882 | 10 | |
| α-helix | 2886-2900 | 15 | |
| α-helix | 2920-2932 | 13 | |
| α-helix | 2936-2943 | 8 | |
| α-helix | 2951-2961 | 11 | |
| α-helix | 2966-2977 | 12 | |
| α-helix | 2985-2987 | 3 | |
| α-helix | 2988-3004 | 17 | |
| α-helix | 3008-3015 | 8 | |
| α-helix | 3016-3021 | 6 | |
| α-helix | 3030-3032 | 3 | |
| α-helix | 3035-3053 | 19 | |
| α-helix | 3060-3068 | 9 | |
| α-helix | 3072-3092 | 21 | |
| α-helix | 3096-3116 | 21 | |
| α-helix | 3122-3142 | 21 | |
| α-helix | 3158-3161 | 4 | |
| α-helix | 3164-3166 | 3 | |
| α-helix | 3176-3196 | 21 | |
| α-helix | 3227-3248 | 22 | |
| α-helix | 3256-3266 | 11 | |
| α-helix | 3270-3287 | 18 | |
| α-helix | 3292-3298 | 7 | |
| α-helix | 3304-3311 | 8 | |
| α-helix | 3320-3343 | 24 | |
| α-helix | 3348-3351 | 4 | |
| α-helix | 3355-3363 | 9 | |
| α-helix | 3370-3393 | 24 | |
| α-helix | 3408-3427 | 20 | |
| α-helix | 3442-3455 | 14 | |
| α-helix | 3459-3474 | 16 | |
| α-helix | 3476-3486 | 11 | |
| β-strand | 3493 | 1 | 16 |
| α-helix | 3499-3507 | 9 | |
| α-helix | 3512-3524 | 13 | |
| α-helix | 3530-3537 | 8 | |
| α-helix | 3548-3561 | 14 | |
| α-helix | 3565-3578 | 14 | |
| α-helix | 3581-3595 | 15 | |
| α-helix | 3606-3613 | 8 | |
| α-helix | 3614-3618 | 5 | |
| α-helix | 3628-3643 | 16 | |
| α-helix | 3658-3668 | 11 | |
| α-helix | 3685-3688 | 4 | |
| β-strand | 3699-3700 | 2 | 17 |
| α-helix | 3701 | 1 | |
| β-strand | 3709 | 1 | 16 |
| α-helix | 3711-3713 | 3 | |
| β-strand | 3718-3719 | 2 | 17 |
| β-strand | 3727-3728 | 2 | 18 |
| β-strand | 3736-3738 | 3 | 18 |
| β-strand | 3741-3742 | 2 | 19 |
| β-strand | 3746-3747 | 2 | 19 |
| β-strand | 3750-3753 | 4 | 18 |
| α-helix | 3759-3777 | 19 | |
| α-helix | 3780-3783 | 4 | |
| β-strand | 3793-3797 | 5 | 18 |
| β-strand | 3800-3803 | 4 | 18 |
| β-strand | 3810-3811 | 2 | 20 |
| α-helix | 3812-3818 | 7 | |
| α-helix | 3822-3823 | 2 | |
| α-helix | 3824-3828 | 5 | |
| α-helix | 3829-3830 | 2 | |
| α-helix | 3835-3840 | 6 | |
| α-helix | 3854-3860 | 7 | |
| α-helix | 3864-3877 | 14 | |
| α-helix | 3882-3890 | 9 | |
| α-helix | 3894-3917 | 24 | |
| α-helix | 3925-3927 | 3 | |
| β-strand | 3928-3931 | 4 | 20 |
| β-strand | 3936-3939 | 4 | 20 |
| α-helix | 3948-3950 | 3 | |
| α-helix | 3965-3968 | 4 | |
| α-helix | 3979-3991 | 13 | |
| α-helix | 3994-3996 | 3 | |
| α-helix | 3998-4001 | 4 | |
| α-helix | 4011-4014 | 4 | |
| α-helix | 4040-4051 | 12 | |
| α-helix | 4056-4068 | 13 | |
| α-helix | 4074-4083 | 10 | |
| α-helix | 4086-4089 | 4 | |
| α-helix | 4090-4092 | 3 | |
| α-helix | 4100-4109 | 10 | |
| α-helix | 4113-4118 | 6 | |
Chain h: 19 helices, 26 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 35-43 | 9 | 63 |
| α-helix | 61-77 | 17 | |
| β-strand | 82-88 | 7 | 63 |
| β-strand | 94 | 1 | 63 |
| β-strand | 103-109 | 7 | 63 |
| α-helix | 113-120 | 8 | |
| α-helix | 127-134 | 8 | |
| α-helix | 143-156 | 14 | |
| β-strand | 161-169 | 9 | 63 |
| α-helix | 175-178 | 4 | |
| α-helix | 180-195 | 16 | |
| β-strand | 199-203 | 5 | 63 |
| α-helix | 239-243 | 5 | |
| α-helix | 251-253 | 3 | |
| β-strand | 257 | 1 | 64 |
| β-strand | 260-262 | 3 | 64 |
| β-strand | 268-274 | 7 | 64 |
| β-strand | 277 | 1 | 65 |
| α-helix | 282-285 | 4 | |
| β-strand | 286-289 | 4 | 66 |
| β-strand | 295 | 1 | 66 |
| β-strand | 298-304 | 7 | 67 |
| α-helix | 313-315 | 3 | |
| β-strand | 316-317 | 2 | 68 |
| β-strand | 318-322 | 5 | 69 |
| β-strand | 325-329 | 5 | 69 |
| α-helix | 331-337 | 7 | |
| β-strand | 344-352 | 9 | 64 |
| α-helix | 353-355 | 3 | |
| β-strand | 366-371 | 6 | 64 |
| α-helix | 378-392 | 15 | |
| β-strand | 394-401 | 8 | 64 |
| β-strand | 409-416 | 8 | 64 |
| β-strand | 419-420 | 2 | 70 |
| β-strand | 426-428 | 3 | 70 |
| β-strand | 431-436 | 6 | 64 |
| α-helix | 440-442 | 3 | |
| β-strand | 443 | 1 | 71 |
| α-helix | 456-468 | 13 | |
| β-strand | 470 | 1 | 71 |
| β-strand | 471 | 1 | 72 |
| α-helix | 481-494 | 14 | |
| α-helix | 500-504 | 5 | |
| α-helix | 511-518 | 8 | |
| α-helix | 521-529 | 9 | |
Chain i: 0 helices, 1 β-strand
| Element | Residues | Length | Sheet |
|---|
| β-strand | 201 | 1 | 72 |
Chain j: 29 helices, 23 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 9-15 | 7 | 73 |
| α-helix | 18-21 | 4 | |
| α-helix | 30-47 | 18 | |
| β-strand | 53-59 | 7 | 73 |
| β-strand | 65 | 1 | 73 |
| β-strand | 77-84 | 8 | 73 |
| α-helix | 88-92 | 5 | |
| α-helix | 93-97 | 5 | |
| α-helix | 107-121 | 15 | |
| β-strand | 130-135 | 6 | 73 |
| α-helix | 147-157 | 11 | |
| β-strand | 160-165 | 6 | 73 |
| α-helix | 199-216 | 18 | |
| α-helix | 217-223 | 7 | |
| β-strand | 224-226 | 3 | 73 |
| α-helix | 227-233 | 7 | |
| α-helix | 237-240 | 4 | |
| α-helix | 244-246 | 3 | |
| β-strand | 248-253 | 6 | 71 |
| β-strand | 257-267 | 11 | 71 |
| β-strand | 279-280 | 2 | 68 |
| β-strand | 289-295 | 7 | 67 |
| β-strand | 305 | 1 | 67 |
| α-helix | 307-309 | 3 | |
| β-strand | 310-316 | 7 | 66 |
| β-strand | 319-322 | 4 | 66 |
| α-helix | 325-331 | 7 | |
| β-strand | 340-347 | 8 | 71 |
| α-helix | 353-355 | 3 | |
| β-strand | 361-366 | 6 | 71 |
| α-helix | 371-386 | 16 | |
| β-strand | 389-395 | 7 | 71 |
| α-helix | 402-403 | 2 | |
| β-strand | 404-413 | 10 | 71 |
| β-strand | 416-424 | 9 | 71 |
| α-helix | 427-429 | 3 | |
| β-strand | 430 | 1 | 65 |
| α-helix | 445-447 | 3 | |
| α-helix | 448-460 | 13 | |
| β-strand | 462 | 1 | 64 |
| β-strand | 464-467 | 4 | 74 |
| β-strand | 472-475 | 4 | 74 |
| α-helix | 485-499 | 15 | |
| α-helix | 504-509 | 6 | |
| α-helix | 510-516 | 7 | |
| α-helix | 520-536 | 17 | |
| α-helix | 596-603 | 8 | |
| α-helix | 616-622 | 7 | |
| α-helix | 629-648 | 20 | |
| α-helix | 652-668 | 17 | |
| α-helix | 675-685 | 11 | |
| α-helix | 695-701 | 7 | |
8 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| DNA-dependent protein kinase catalytic subunit | A, F | protein | 4128 | Homo sapiens | P78527 |
| DNA repair protein XRCC4 | K, L, N, O | protein | 336 | Homo sapiens | Q13426 (AlphaFold model) |
| DNA ligase 4 | M, P | protein | 911 | Homo sapiens | P49917 (AlphaFold model) |
| Non-homologous end-joining factor 1 | Q, R | protein | 299 | Homo sapiens | Q9H9Q4 (AlphaFold model) |
| X-ray repair cross-complementing protein 6 | a, h | protein | 609 | Homo sapiens | P12956 |
| X-ray repair cross-complementing protein 5 | b, j | protein | 732 | Homo sapiens | P13010 |
| Protein PAXX | c, i | protein | 204 | Homo sapiens | Q9BUH6 |
| DNA (26-mer) | D | DNA | 27 | Homo sapiens | |
| DNA (27-mer) | E | DNA | 28 | Homo sapiens | |
| DNA (28-mer) | I | DNA | 24 | Homo sapiens | |
| DNA (24-mer) | J | DNA | 24 | Homo sapiens | |
Sequence of entity 1 (A, F), FASTA
>8BHV_1 DNA-dependent protein kinase catalytic subunit (chains A, F)
MAGSGAGVRCSLLRLQETLSAADRCGAALAGHQLIRGLGQECVLSSSPAVLALQTSLVFS
RDFGLLVFVRKSLNSIEFRECREEILKFLCIFLEKMGQKIAPYSVEIKNTCTSVYTKDRA
AKCKIPALDLLIKLLQTFRSSRLMDEFKIGELFSKFYGELALKKKIPDTVLEKVYELLGL
LGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE
DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKW
CAHTNVELKKAALSALESFLKQVSNMVAKNAEMHKNKLQYFMEQFYGIIRNVDSNNKELS
IAIRGYGLFAGPCKVINAKDVDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSFLQSVASV
LLYLDTVPEVYTPVLEHLVVMQIDSFPQYSPKMQLVCCRAIVKVFLALAAKGPVLRNCIS
TVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQM
MDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGV
WMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRL
PLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAVKMKQ
YKDELLASCLTFLLSLPHNIIELDVRAYVPALQMAFKLGLSYTPLAEVGLNALEEWSIYI
DRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSRAAQKGFNKVVLKHLKKTKNL
SSNEAISLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDREKRLSFAVPFRE
MKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGKATQMPEGGQGAPPMYQ
LYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGIVDP
VDSTLRDFCGRCIREFLKWSIKQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASL
AFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEK
KHVSLNKAKKRRLPRGFPPSASLCLLDLVKWLLAHCGRPQTECRHKSIELFYKFVPLLPG
NRSPNLWLKDVLKEEGVSFLINTFEGGGCGQPSGILAQPTLLYLRGPFSLQATLCWLDLL
LAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFLESIAMHDIIAAEKCFGTGAAGN
RTSPQEGERYNYSKCTVVVRIMEFTTTLLNTSPEGWKLLKKDLCNTHLMRVLVQTLCEPA
SIGFNIGDVQVMAHLPDVCVNLMKALKMSPYKDILETHLREKITAQSIEELCAVNLYGPD
AQVDRSRLAAVVSACKQLHRAGLLHNILPSQSTDLHHSVGTELLSLVYKGIAPGDERQCL
PSLDLSCKQLASGLLELAFAFGGLCERLVSLLLNPAVLSTASLGSSQGSVIHFSHGEYFY
SLFSETINTELLKNLDLAVLELMQSSVDNTKMVSAVLNGMLDQSFRERANQKHQGLKLAT
TILQHWKKCDSWWAKDSPLETKMAVLALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLA
DTKLDLHLKGQAVTLLPFFTSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYV
DCMKKFLDALELSQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLES
VYEMFRKDDPRLSFTRQSFVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLKSRFTKLNE
STFDTQITKKMGYYKILDVMYSRLPKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCY
DAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFSEKPEKNLLIFEN
LIDLKRRYNFPVEVEVPMERKKKYIEIRKEAREAANGDSDGPSYMSSLSYLADSTLSEEM
SQFDFSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTAL
VKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPY
AKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGLATPTGVPKDEVLANRLLNFLM
KHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIV
MANDLPPYDPQCGIQSSEYFQALVNNMSFVRYKEVYAAAAEVLGLILRYVMERKNILEES
LCELVAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEV
VLCRVEGMTELYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNPVVE
FVSHPSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLI
IRNFWSHETRLPSNTLDRLLALNSLYSPKIEVHFLSLATNFLLEMTSMSPDYPNPMFEHP
LSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQ
QHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDF
GKKRLGLPGDEVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSE
LKMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEM
DKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAVSAGC
LASLQQPVGIRLLEEALLRLLPAELPAKRVRGKARLPPDVLRWVELAKLYRSIGEYDVLR
GIFTSEIGTKQITQSALLAEARSDYSEAAKQYDEALNKQDWVDGEPTEAEKDFWELASLD
CYNHLAEWKSLEYCSTASIDSENPPDLNKIWSEPFYQETYLPYMIRSKLKLLLQGEADQS
LLTFIDKAMHGELQKAILELHYSQELSLLYLLQDDVDRAKYYIQNGIQSFMQNYSSIDVL
LHQSRLTKLQSVQALTEIQEFISFISKQGNLSSQVPLKRLLNTWTNRYPDAKMDPMNIWD
DIITNRCFFLSKIEEKLTPLPEDNSMNVDQDGDPSDRMEVQEQEEDISSLIRSCKFSMKM
KMIDSARKQNNFSLAMKLLKELHKESKTRDDWLVSWVQSYCRLSHCRSRSQGCSEQVLTV
LKTVSLLDENNVSSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL
ELSGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFC
DQQLRKEEENASVIDSAELQAYPALVVEKMLKALKLNSNEARLKFPRLLQIIERYPEETL
SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESY
SFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDWSNDVRAELAKTP
VNKKNIEKMYERMYAALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFN
DITNMLLLKMNKDSKPPGNLKECSPWMSDFKVEFLRNELEIPGQYDGRGKPLPEYHVRIA
GFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSA
CSQRALQLRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYK
DWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPADLLKRAFVRMSTSPEAFLAL
RSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMP
FRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKM
LKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAV
ARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEPWM
Sequence of entity 2 (K, L, N, O), FASTA
>8BHV_2 DNA repair protein XRCC4 (chains K, L, N, O)
MERKISRIHLVSEPSITHFLQVSWEKTLESGFVITLTDGHSAWTGTVSESEISQEADDMA
MEKGKYVGELRKALLSGAGPADVYTFNFSKESCYFFFEKNLKDVSFRLGSFNLEKVENPA
EVIRELICYCLDTIAENQAKNEHLQKENERLLRDWNDVQGRFEKCVSAKEALETDLYKRF
ILVLNEKKTKIRSLHNKLLNAAQEREKDIKQEGETAICSEMTADRDPVYDESTDEESENQ
TDLSGLASAAVSKDDSIISSLDVTDIAPSRKRRQRMQRNLGTEPKMAPQENQLQEKENSR
PDSSLPETSKKEHISAENMSLETLRNSSPEDLFDEI
Sequence of entity 3 (M, P), FASTA
>8BHV_3 DNA ligase 4 (chains M, P)
MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV
TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG
DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA
LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI
TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD
QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL
QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE
AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM
SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC
GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE
QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE
DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV
VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG
IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI
KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK
CELQEENQYLI
Sequence of entity 4 (Q, R), FASTA
>8BHV_4 Non-homologous end-joining factor 1 (chains Q, R)
MEELEQGLLMQPWAWLQLAENSLLAKVFITKQGYALLVSDLQQVWHEQVDTSVVSQRAKE
LNKRLTAPPAAFLCHLDNLLRPLLKDAAHPSEATFSCDCVADALILRVRSELSGLPFYWN
FHCMLASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLK
TEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHT
SNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQLSKVKRKKPRGLFS
Sequence of entity 5 (a, h), FASTA
>8BHV_5 X-ray repair cross-complementing protein 6 (chains a, h)
MSGWESYYKTEGDEEAEEEQEENLEASGDYKYSGRDSLIFLVDASKAMFESQSEDELTPF
DMSIQCIQSVYISKIISSDRDLLAVVFYGTEKDKNSVNFKNIYVLQELDNPGAKRILELD
QFKGQQGQKRFQDMMGHGSDYSLSEVLWVCANLFSDVQFKMSHKRIMLFTNEDNPHGNDS
AKASRARTKAGDLRDTGIFLDLMHLKKPGGFDISLFYRDIISIAEDEDLRVHFEESSKLE
DLLRKVRAKETRKRALSRLKLKLNKDIVISVGIYNLVQKALKPPPIKLYRETNEPVKTKT
RTFNTSTGGLLLPSDTKRSQIYGSRQIILEKEETEELKRFDDPGLMLMGFKPLVLLKKHH
YLRPSLFVYPEESLVIGSSTLFSALLIKCLEKEVAALCRYTPRRNIPPYFVALVPQEEEL
DDQKIQVTPPGFQLVFLPFADDKRKMPFTEKIMATPEQVGKMKAIVEKLRFTYRSDSFEN
PVLQQHFRNLEALALDLMEPEQAVDLTLPKVEAMNKRLGSLVDEFKELVYPPDYNPEGKV
TKRKHDNEGSGSKRPKVEYSEEELKTHISKGTLGKFTVPMLKEACRAYGLKSGLKKQELL
EALTKHFQD
Sequence of entity 6 (b, j), FASTA
>8BHV_6 X-ray repair cross-complementing protein 5 (chains b, j)
MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFG
TDGTDNPLSGGDQYQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQH
ETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGD
GPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKI
ERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDD
DETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQ
VLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLV
YVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTT
KIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLI
EAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRV
LVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLK
ALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFE
EGGDVDDLLDMI
Sequence of entity 7 (c, i), FASTA
>8BHV_7 Protein PAXX (chains c, i)
MDPLSPPLCTLPPGPEPPRFVCYCEGEESGEGDRGGFNLYVTDAAELWSTCFTPDSLAAL
KARFGLSAAEDITPRFRAACEQQAVALTLQEDRASLTLSGGPSALAFDLSKVPGPEAAPR
LRALTLGLAKRVWSLERRLAAAEETAVSPRKSPRPAGPQLFLPDPDPQRGGPGPGVRRRC
PGESLINPGFKSKKPAGGVDFDET
Sequence of entity 8 (D), FASTA
>8BHV_8 DNA (26-MER) (chains D)
CCAAATAATAGTTTTTAGTTTATTGGG
Sequence of entity 9 (E), FASTA
>8BHV_9 DNA (27-MER) (chains E)
GCTAATAAACTAAAAACTATTATTATGG
Sequence of entity 10 (I), FASTA
>8BHV_10 DNA (28-MER) (chains I)
ATAAACTAAAAACTATTATTATGG
Sequence of entity 11 (J), FASTA
>8BHV_11 DNA (24-MER) (chains J)
CATAATAATAGTTTTTAGTTTATT
Primary citation
PAXX binding to the NHEJ machinery explains functional redundancy with XLF. Seif-El-Dahan, M., Kefala-Stavridi, A., Frit, P. et al. Sci Adv (2023) 9:eadg2834-eadg2834. DOI 10.1126/sciadv.adg2834 · PubMed
Other PDB entries of the same protein (UniProt P78527), best resolution first:
- 7Z87 2.91 Å, DNA-PK in the active state
- 7OTY 2.96 Å, DNA-PKcs in complex with M3814
- 7OTW 2.99 Å, DNA-PKcs in complex with AZD7648
- 7SGL 3.0 Å, DNA-PK complex of DNA end processing
- 7K11 3.21 Å, CryoEM structure of inactivated-form FATKIN domain of DNA-PK
- 6ZFP 3.24 Å, Cryo-EM structure of DNA-PKcs (State 2)
- 7OTV 3.24 Å, DNA-PKcs in complex with wortmannin
- 7K10 3.3 Å, CryoEM structure of activated-form FATKIN domain of DNA-PK
- 7SU3 3.3 Å, CryoEM structure of DNA-PK complex VII
- 7OTM 3.33 Å, Cryo-EM structure of DNA-PKcs in complex with NU7441
- 7TYR 3.33 Å, Cryo-EM structure of the basal state of the Artemis:DNA-PKcs complex (see COMPND 13/14)
- 7Z88 3.33 Å, DNA-PK in the intermediate state
Browse structure collections
About this viewer
MolViewer shows 8BHV directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.