8CSP: 28S ribosomal protein S34, mitochondrial
Human mitochondrial small subunit assembly intermediate (State A). Determined by electron microscopy at 2.66 Å resolution. Released 14 Dec 2022.
- Method
- Electron microscopy
- Resolution
- 2.66 Å
- Organism
- Homo sapiens
- Chains
- 33
- Atoms
- 69,302
- Mol. weight
- 1348.95 kDa
- Ligands
- GDP, ATP, ZN, FES
- Released
- 14 Dec 2022
Explore 8CSP in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8CSP contains 389 α-helices and 237 β-strands across 31 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 0: 16 helices, 12 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 10-24 | 15 | |
| α-helix | 27-29 | 3 | |
| α-helix | 30-33 | 4 | |
| β-strand | 37 | 1 | 1 |
| β-strand | 42 | 1 | 1 |
| α-helix | 48 | 1 | |
| β-strand | 49 | 1 | 1 |
| α-helix | 50-51 | 2 | |
| α-helix | 52-60 | 9 | |
| β-strand | 62 | 1 | 2 |
| α-helix | 64-68 | 5 | |
| α-helix | 72-75 | 4 | |
| β-strand | 79-82 | 4 | 2 |
| α-helix | 83-88 | 6 | |
| β-strand | 94-102 | 9 | 2 |
| β-strand | 112-120 | 9 | 2 |
| β-strand | 123-124 | 2 | 2 |
| β-strand | 129-130 | 2 | 2 |
| α-helix | 131 | 1 | |
| β-strand | 139-141 | 3 | 2 |
| α-helix | 142-143 | 2 | |
| α-helix | 147-151 | 5 | |
| β-strand | 163-165 | 3 | 3 |
| α-helix | 166-167 | 2 | |
| α-helix | 168-180 | 13 | |
| α-helix | 187-189 | 3 | |
| β-strand | 190-192 | 3 | 3 |
| α-helix | 213-215 | 3 | |
Chain 1: 17 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 56-59 | 4 | |
| α-helix | 66-69 | 4 | |
| β-strand | 86 | 1 | 5 |
| α-helix | 89-91 | 3 | |
| α-helix | 96-98 | 3 | |
| α-helix | 103-106 | 4 | |
| α-helix | 116-125 | 10 | |
| α-helix | 126-129 | 4 | |
| α-helix | 140-146 | 7 | |
| β-strand | 149-157 | 9 | 6 |
| β-strand | 162 | 1 | 7 |
| α-helix | 166-169 | 4 | |
| β-strand | 171-176 | 6 | 6 |
| α-helix | 177-179 | 3 | |
| α-helix | 184-194 | 11 | |
| α-helix | 195-197 | 3 | |
| β-strand | 198-199 | 2 | 6 |
| β-strand | 204-209 | 6 | 6 |
| α-helix | 215-234 | 20 | |
| α-helix | 240-242 | 3 | |
| α-helix | 257-273 | 17 | |
| α-helix | 287-301 | 15 | |
| α-helix | 306-320 | 15 | |
Chain 4: 40 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 59-60 | 2 | |
| β-strand | 61-64 | 4 | 9 |
| α-helix | 69-77 | 9 | |
| α-helix | 100-123 | 24 | |
| α-helix | 125-127 | 3 | |
| β-strand | 134 | 1 | 7 |
| α-helix | 138-140 | 3 | |
| α-helix | 154-162 | 9 | |
| α-helix | 166-178 | 13 | |
| α-helix | 181-184 | 4 | |
| α-helix | 185-198 | 14 | |
| α-helix | 236-239 | 4 | |
| α-helix | 243-250 | 8 | |
| α-helix | 256-268 | 13 | |
| α-helix | 272-284 | 13 | |
| α-helix | 291-303 | 13 | |
| α-helix | 309-325 | 17 | |
| α-helix | 328-330 | 3 | |
| α-helix | 332-342 | 11 | |
| α-helix | 343-349 | 7 | |
| α-helix | 350-363 | 14 | |
| α-helix | 365-367 | 3 | |
| α-helix | 369-379 | 11 | |
| α-helix | 392-400 | 9 | |
| α-helix | 412-414 | 3 | |
| α-helix | 415-426 | 12 | |
| α-helix | 429-439 | 11 | |
| β-strand | 441 | 1 | 10 |
| α-helix | 444-448 | 5 | |
| α-helix | 451-468 | 18 | |
| α-helix | 471-481 | 11 | |
| α-helix | 490-503 | 14 | |
| α-helix | 506-508 | 3 | |
| α-helix | 509-518 | 10 | |
| α-helix | 525-536 | 12 | |
| α-helix | 542-560 | 19 | |
| α-helix | 573-585 | 13 | |
| α-helix | 589-602 | 14 | |
| α-helix | 605-607 | 3 | |
| α-helix | 608-621 | 14 | |
| α-helix | 624-636 | 13 | |
| α-helix | 642-652 | 11 | |
| α-helix | 657-666 | 10 | |
Chain 5: 22 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 13-17 | 5 | |
| α-helix | 18-25 | 8 | |
| α-helix | 41-50 | 10 | |
| β-strand | 58-62 | 5 | 13 |
| α-helix | 68-75 | 8 | |
| β-strand | 80-85 | 6 | 13 |
| α-helix | 91-100 | 10 | |
| β-strand | 105-109 | 5 | 13 |
| α-helix | 117-119 | 3 | |
| α-helix | 123-125 | 3 | |
| β-strand | 136-140 | 5 | 13 |
| α-helix | 144-160 | 17 | |
| α-helix | 163-166 | 4 | |
| β-strand | 171-177 | 7 | 13 |
| α-helix | 178-184 | 7 | |
| α-helix | 186-187 | 2 | |
| α-helix | 195-201 | 7 | |
| β-strand | 204-212 | 9 | 13 |
| α-helix | 214-216 | 3 | |
| β-strand | 225-232 | 8 | 13 |
| α-helix | 242-253 | 12 | |
| α-helix | 260-264 | 5 | |
| α-helix | 265-267 | 3 | |
| α-helix | 270-272 | 3 | |
| α-helix | 273-283 | 11 | |
| α-helix | 292-294 | 3 | |
| α-helix | 297-312 | 16 | |
| α-helix | 315-319 | 5 | |
| α-helix | 322-326 | 5 | |
Chain 7: 18 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 36-37 | 2 | 21 |
| α-helix | 43-46 | 4 | |
| α-helix | 49-51 | 3 | |
| α-helix | 57-60 | 4 | |
| β-strand | 61-62 | 2 | 22 |
| α-helix | 65-75 | 11 | |
| α-helix | 81-96 | 16 | |
| α-helix | 97-102 | 6 | |
| α-helix | 103-115 | 13 | |
| α-helix | 134-141 | 8 | |
| α-helix | 152-180 | 29 | |
| β-strand | 189-192 | 4 | 22 |
| α-helix | 198-207 | 10 | |
| β-strand | 214-217 | 4 | 22 |
| α-helix | 221-231 | 11 | |
| β-strand | 245-248 | 4 | 22 |
| β-strand | 259-265 | 7 | 22 |
| α-helix | 268-270 | 3 | |
| α-helix | 274-287 | 14 | |
| β-strand | 288-297 | 10 | 22 |
| α-helix | 300-314 | 15 | |
| β-strand | 327-331 | 5 | 22 |
| α-helix | 338-339 | 2 | |
| β-strand | 349-354 | 6 | 22 |
| α-helix | 355-357 | 3 | |
| β-strand | 365-376 | 12 | 22 |
| β-strand | 387-388 | 2 | 23 |
| β-strand | 393-395 | 3 | 23 |
| β-strand | 398-404 | 7 | 23 |
| β-strand | 410-415 | 6 | 23 |
| α-helix | 417-420 | 4 | |
| α-helix | 422-430 | 9 | |
| β-strand | 436 | 1 | 23 |
| β-strand | 439-440 | 2 | 21 |
Chain 8: 19 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 57-58 | 2 | |
| β-strand | 63-67 | 5 | 24 |
| α-helix | 87-98 | 12 | |
| α-helix | 102-107 | 6 | |
| α-helix | 117-138 | 22 | |
| α-helix | 140-144 | 5 | |
| β-strand | 146-151 | 6 | 24 |
| α-helix | 155-162 | 8 | |
| α-helix | 168-188 | 21 | |
| β-strand | 192-198 | 7 | 25 |
| α-helix | 204-218 | 15 | |
| β-strand | 225-232 | 8 | 25 |
| β-strand | 235-240 | 6 | 25 |
| α-helix | 242-250 | 9 | |
| α-helix | 252-255 | 4 | |
| β-strand | 257-262 | 6 | 25 |
| α-helix | 272-277 | 6 | |
| α-helix | 278-287 | 10 | |
| β-strand | 296-298 | 3 | 24 |
| α-helix | 299 | 1 | |
| β-strand | 305 | 1 | 24 |
| α-helix | 309-311 | 3 | |
| α-helix | 312-318 | 7 | |
| α-helix | 319-321 | 3 | |
| β-strand | 324-325 | 2 | 25 |
| α-helix | 326-334 | 9 | |
| β-strand | 344-347 | 4 | 24 |
| α-helix | 353-361 | 9 | |
| α-helix | 363-366 | 4 | |
| β-strand | 369-371 | 3 | 24 |
Chain 9: 24 helices, 31 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 75-77 | 3 | |
| α-helix | 87-114 | 28 | |
| α-helix | 180-192 | 13 | |
| β-strand | 195-196 | 2 | 26 |
| α-helix | 198-204 | 7 | |
| α-helix | 206-209 | 4 | |
| β-strand | 215-222 | 8 | 27 |
| α-helix | 231-233 | 3 | |
| α-helix | 234-237 | 4 | |
| β-strand | 242-248 | 7 | 27 |
| α-helix | 260-274 | 15 | |
| β-strand | 278-279 | 2 | 27 |
| β-strand | 309-315 | 7 | 27 |
| β-strand | 317 | 1 | 28 |
| β-strand | 322 | 1 | 28 |
| α-helix | 324-331 | 8 | |
| β-strand | 340-343 | 4 | 27 |
| β-strand | 345 | 1 | 27 |
| β-strand | 346 | 1 | 26 |
| α-helix | 347-349 | 3 | |
| α-helix | 351-359 | 9 | |
| β-strand | 364 | 1 | 29 |
| α-helix | 371-374 | 4 | |
| β-strand | 376-379 | 4 | 30 |
| α-helix | 380 | 1 | |
| β-strand | 386-389 | 4 | 30 |
| β-strand | 391 | 1 | 31 |
| β-strand | 392 | 1 | 29 |
| α-helix | 393-395 | 3 | |
| α-helix | 397-400 | 4 | |
| β-strand | 493 | 1 | 31 |
| β-strand | 494-496 | 3 | 27 |
| α-helix | 498 | 1 | |
| β-strand | 499-500 | 2 | 26 |
| α-helix | 501-502 | 2 | |
| α-helix | 506-509 | 4 | |
| α-helix | 512-518 | 7 | |
| β-strand | 527-531 | 5 | 32 |
| β-strand | 535-539 | 5 | 33 |
| β-strand | 543-548 | 6 | 33 |
| β-strand | 554-560 | 7 | 32 |
| β-strand | 566-570 | 5 | 33 |
| α-helix | 571-581 | 11 | |
| α-helix | 593-599 | 7 | |
| α-helix | 601-602 | 2 | |
| β-strand | 603-609 | 7 | 33 |
| β-strand | 621-624 | 4 | 32 |
| β-strand | 629-635 | 7 | 32 |
| α-helix | 636 | 1 | |
| β-strand | 642-648 | 7 | 33 |
| β-strand | 654-656 | 3 | 32 |
| β-strand | 670 | 1 | 34 |
| β-strand | 676 | 1 | 32 |
| β-strand | 677 | 1 | 34 |
| α-helix | 681-684 | 4 | |
Chain a: 12 helices, 14 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 112-120 | 9 | 35 |
| α-helix | 126-134 | 9 | |
| β-strand | 154-158 | 5 | 35 |
| β-strand | 161-167 | 7 | 35 |
| α-helix | 189-194 | 6 | |
| β-strand | 199-205 | 7 | 35 |
| α-helix | 217-225 | 9 | |
| β-strand | 231-236 | 6 | 35 |
| α-helix | 238-240 | 3 | |
| α-helix | 246-254 | 9 | |
| β-strand | 258-259 | 2 | 36 |
| β-strand | 262-263 | 2 | 36 |
| β-strand | 302-307 | 6 | 35 |
| β-strand | 309 | 1 | 37 |
| β-strand | 314 | 1 | 37 |
| α-helix | 316-325 | 10 | |
| α-helix | 327 | 1 | |
| β-strand | 328-329 | 2 | 35 |
| α-helix | 344-359 | 16 | |
| α-helix | 364-367 | 4 | |
| β-strand | 369-377 | 9 | 38 |
| β-strand | 383-391 | 9 | 38 |
| α-helix | 394-401 | 8 | |
| α-helix | 403-405 | 3 | |
| α-helix | 406-422 | 17 | |
| β-strand | 427-435 | 9 | 38 |
23 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 28S ribosomal protein S34, mitochondrial | 0 | protein | 218 | Homo sapiens | P82930 (AlphaFold model) |
| 28S ribosomal protein S35, mitochondrial | 1 | protein | 323 | Homo sapiens | P82673 (AlphaFold model) |
| Pentatricopeptide repeat domain-containing protein 3, mitochondrial | 4 | protein | 689 | Homo sapiens | Q96EY7 (AlphaFold model) |
| Dimethyladenosine transferase 1, mitochondrial | 5 | protein | 346 | Homo sapiens | Q8WVM0 (AlphaFold model) |
| Methyltransferase-like protein 17, mitochondrial | 7 | protein | 456 | Homo sapiens | Q9H7H0 |
| Malonyl-CoA-acyl carrier protein transacylase, mitochondrial | 8 | protein | 390 | Homo sapiens | Q8IVS2 |
| Nitric oxide-associated protein 1 | 9 | protein | 698 | Homo sapiens | Q8NC60 |
| 12S mitochondrial rRNA | A | RNA | 955 | Homo sapiens | |
| 28S ribosomal protein S2, mitochondrial | B | protein | 296 | Homo sapiens | Q9Y399 |
| 28S ribosomal protein S24, mitochondrial | C | protein | 167 | Homo sapiens | Q96EL2 |
| 28S ribosomal protein S5, mitochondrial | D | protein | 430 | Homo sapiens | P82675 |
| 28S ribosomal protein S6, mitochondrial | E | protein | 125 | Homo sapiens | P82932 |
21 more molecules are not listed.
Sequence of entity 1 (0), FASTA
>8CSP_1 28S ribosomal protein S34, mitochondrial (chains 0)
MARKKVRPRLIAELARRVRALREQLNRPRDSQLYAVDYETLTRPFSGRRLPVRAWADVRR
ESRLLQLLGRLPLFGLGRLVTRKSWLWQHDEPCYWRLTRVRPDYTAQNLDHGKAWGILTF
KGKTESEAREIEHVMYHDWRLVPKHEEEAFTAFTPAPEDSLASVPYPPLLRAMIIAERQK
NGDTSTEEPMLNVQRIRMEPWDYPAKQEDKGRAKGTPV
Sequence of entity 2 (1), FASTA
>8CSP_2 28S ribosomal protein S35, mitochondrial (chains 1)
MAAAALPAWLSLQSRARTLRAFSTAVYSATPVPTPSLPERTPGNERPPRRKALPPRTEKM
AVDQDWPSVYPVAAPFKPSAVPLPVRMGYPVKKGVPMAKEGNLELLKIPNFLHLTPVAIK
KHCEALKDFCTEWPAALDSDEKCEKHFPIEIDSTDYVSSGPSVRNPRARVVVLRVKLSSL
NLDDHAKKKLIKLVGERYCKTTDVLTIKTDRCPLRRQNYDYAVYLLTVLYHESWNTEEWE
KSKTEADMEEYIWENSSSERNILETLLQMKAAEKNMEINKEELLGTKEIEEYKKSVVSLK
NEEENENSISQYKESVKRLLNVT
Sequence of entity 3 (4), FASTA
>8CSP_3 Pentatricopeptide repeat domain-containing protein 3, mitochondrial (chains 4)
MAVVSAVRWLGLRSRLGQPLTGRRAGLCEQARSCRFYSGSATLSKVEGTDVTGIEEVVIP
KKKTWDKVAVLQALASTVNRDTTAVPYVFQDDPYLMPASSLESRSFLLAKKSGENVAKFI
INSYPKYFQKDIAEPHIPCLMPEYFEPQIKDISEAALKERIELRKVKASVDMFDQLLQAG
TTVSLETTNSLLDLLCYYGDQEPSTDYHFQQTGQSEALEEENDETSRRKAGHQFGVTWRA
KNNAERIFSLMPEKNEHSYCTMIRGMVKHRAYEQALNLYTELLNNRLHADVYTFNALIEA
TVCAINEKFEEKWSKILELLRHMVAQKVKPNLQTFNTILKCLRRFHVFARSPALQVLREM
KAIGIEPSLATYHHIIRLFDQPGDPLKRSSFIIYDIMNELMGKRFSPKDPDDDKFFQSAM
SICSSLRDLELAYQVHGLLKTGDNWKFIGPDQHRNFYYSKFFDLICLMEQIDVTLKWYED
LIPSAYFPHSQTMIHLLQALDVANRLEVIPKIWKDSKEYGHTFRSDLREEILMLMARDKH
PPELQVAFADCAADIKSAYESQPIRQTAQDWPATSLNCIAILFLRAGRTQEAWKMLGLFR
KHNKIPRSELLNELMDSAKVSNSPSQAIEVVELASAFSLPICEGLTQRVMSDFAINQEQK
EALSNLTALTSDSDTDSSSDSDSDTSEGK
Sequence of entity 4 (5), FASTA
>8CSP_4 Dimethyladenosine transferase 1, mitochondrial (chains 5)
MAASGKLSTCRLPPLPTIREIIKLLRLQAAKQLSQNFLLDLRLTDKIVRKAGNLTNAYVY
EVGPGPGGITRSILNADVAELLVVEKDTRFIPGLQMLSDAAPGKLRIVHGDVLTFKVEKA
FSESLKRPWEDDPPNVHIIGNLPFSVSTPLIIKWLENISCRDGPFVYGRTQMTLTFQKEV
AERLAANTGSKQRSRLSVMAQYLCNVRHIFTIPGQAFVPKPEVDVGVVHFTPLIQPKIEQ
PFKLVEKVVQNVFQFRRKYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISHF
KSLCDVYRKMCDEDPQLFAYNFREELKRRKSKNEEKEEDDAENYRL
Sequence of entity 5 (7), FASTA
>8CSP_5 Methyltransferase-like protein 17, mitochondrial (chains 7)
MAAALKCLLTLGRWCPGLGVAPQARALAALVPGVTQVDNKSGFLQKRPHRQHPGILKLPH
VRLPQALANGAQLLLLGSAGPTMENQVQTLTSYLWSRHLPVEPEELQRRARHLEKKFLEN
PDLSQTEEKLRGAVLHALRKTTYHWQELSYTEGLSLVYMAARLDGGFAAVSRAFHEIRAR
NPAFQPQTLMDFGSGTGSVTWAAHSIWGQSLREYMCVDRSAAMLVLAEKLLKGGSESGEP
YIPGVFFRQFLPVSPKVQFDVVVSAFSLSELPSKADRTEVVQTLWRKTGHFLVLVENGTK
AGHSLLMDARDLVLKGKEKSPLDPRPGFVFAPCPHELPCPQLTNLACSFSQAYHPIPFSW
NKKPKEEKFSMVILARGSPEEAHRWPRITQPVLKRPRHVHCHLCCPDGHMQHAVLTARRH
GRDLYRCARVSSWGDLLPVLTPSAFPPSTAQDPSES
Sequence of entity 6 (8), FASTA
>8CSP_6 Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (chains 8)
MSVRVARVAWVRGLGASYRRGASSFPVPPPGAQGVAELLRDATGAEEEAPWAATERRMPG
QCSVLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHC
QPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEGLYAVKIRAE
AMQEASEAVPSGMLSVLGQPQSKFNFACLEAREHCKSLGIENPVCEVSNYLFPDCRVISG
HQEALRFLQKNSSKFHFRRTRMLPVSGAFHTRLMEPAVEPLTQALKAVDIKKPLVSVYSN
VHAHRYRHPGHIHKLLAQQLVSPVKWEQTMHAIYERKKGRGFPQTFEVGPGRQLGAILKS
CNMQAWKSYSAVDVLQTLEHVDLDPQEPPR
Sequence of entity 7 (9), FASTA
>8CSP_7 Nitric oxide-associated protein 1 (chains 9)
MLPARLPFRLLSLFLRGSAPTAARHGLREPLLERRCAAASSFQHSSSLGRELPYDPVDTE
GFGEGGDMQERFLFPEYILDPEPQPTREKQLQELQQQQEEEERQRQQRREERRQQNLRAR
SREHPVVGHPDPALPPSGVNCSGCGAELHCQDAGVPGYLPREKFLRTAEADGGLARTVCQ
RCWLLSHHRRALRLQVSREQYLELVSAALRRPGPSLVLYMVDLLDLPDALLPDLPALVGP
KQLIVLGNKVDLLPQDAPGYRQRLRERLWEDCARAGLLLAPGHQGPQRPVKDEPQDGENP
NPPNWSRTVVRDVRLISAKTGYGVEELISALQRSWRYRGDVYLVGATNAGKSTLFNTLLE
SDYCTAKGSEAIDRATISPWPGTTLNLLKFPICNPTPYRMFKRHQRLKKDSTQAEEDLSE
QEQNQLNVLKKHGYVVGRVGRTFLYSEEQKDNIPFEFDADSLAFDMENDPVMGTHKSTKQ
VELTAQDVKDAHWFYDTPGITKENCILNLLTEKEVNIVLPTQSIVPRTFVLKPGMVLFLG
AIGRIDFLQGNQSAWFTVVASNILPVHITSLDRADALYQKHAGHTLLQIPMGGKERMAGF
PPLVAEDIMLKEGLGASEAVADIKFSSAGWVSVTPNFKDRLHLRGYTPEGTVLTVRPPLL
PYIVNIKGQRIKKSVAYKTKKPPSLMYNVRKKKGKINV
Sequence of entity 8 (A), FASTA
>8CSP_8 12S mitochondrial rRNA (chains A)
AAUAGGUUUGGUCCUAGCCUUUCUAUUAGCUCUUAGUAAGAUUACACAUGCAAGCAUCCC
CGUUCCAGUGAGUUCACCCUCUAAAUCACCACGAUCAAAAGGGACAAGCAUCAAGCACGC
AGCAAUGCAGCUCAAAACGCUUAGCCUAGCCACACCCCCACGGGAAACAGCAGUGAUUAA
CCUUUAGCAAUAAACGAAAGUUUAACUAAGCUAUACUAACCCCAGGGUUGGUCAAUUUCG
UGCCAGCCACCGCGGUCACACGAUUAACCCAAGUCAAUAGAAGCCGGCGUAAAGAGUGUU
UUAGAUCACCCCCUCCCCAAUAAAGCUAAAACUCACCUGAGUUGUAAAAAACUCCAGUUG
ACACAAAAUAGACUACGAAAGUGGCUUUAACAUAUCUGAACACACAAUAGCUAAGACCCA
AACUGGGAUUAGAUACCCCACUAUGCUUAGCCCUAAACCUCAACAGUUAAAUCAACAAAA
CUGCUCGCCAGAACACUACGAGCCACAGCUUAAAACUCAAAGGACCUGGCGGUGCUUCAU
AUCCCUCUAGAGGAGCCUGUUCUGUAAUCGAUAAACCCCGAUCAACCUCACCACCUCUUG
CUCAGCCUAUAUACCGCCAUCUUCAGCAAACCCUGAUGAAGGCUACAAAGUAAGCGCAAG
UACCCACGUAAAGACGUUAGGUCAAGGUGUAGCCCAUGAGGUGGCAAGAAAUGGGCUACA
UUUUCUACCCCAGAAAACUACGAUAGCCCUUAUGAAACUUAAGGGUCGAAGGUGGAUUUA
GCAGUAAACUGAGAGUAGAGUGCUUAGUUGAACAGGGCCCUGAAGCGCGUACACACCGCC
CGUCACCCUCCUCAAGUAUACUUCAAAGGACAUUUAACUAAAACCCCUACGCAUUUAUAU
AGAGGAGACAAGUCGUAACAUGGUAAGUGUACUGGAAAGUGCACUUGGACGAACC
Sequence of entity 9 (B), FASTA
>8CSP_9 28S ribosomal protein S2, mitochondrial (chains B)
MATSSAALPRILGAGARAPSRWLGFLGKATPRPARPSRRTLGSATALMIRESEDSTDFND
KILNEPLKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFMEPYIFGSRLDHDIIDLEQ
TATHLQLALNFTAHMAYRKGIILFISRNRQFSYLIENMARDCGEYAHTRYFRGGMLTNAR
LLFGPTVRLPDLIIFLHTLNNIFEPHVAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGND
DSPLAVHLYCRLFQTAITRAKEKRQQVEALYRLQGQKEPGDQGPAHPPGADMSHSL
Sequence of entity 10 (C), FASTA
>8CSP_10 28S ribosomal protein S24, mitochondrial (chains C)
MAASVCSGLLGPRVLSWSRELPCAWRALHTSPVCAKNRAARVRVSKGDKPVTYEEAHAPH
YIAHRKGWLSLHTGNLDGEDHAAERTVEDVFLRKFMWGTFPGCLADQLVLKRRGNQLEIC
AVVLRQLSPHKYYFLVGYSETLLSYFYKCPVRLHLQTVPSKVVYKYL
Sequence of entity 11 (D), FASTA
>8CSP_11 28S ribosomal protein S5, mitochondrial (chains D)
MATAVRAVGCLPVLCSGTAGHLLGRQCSLNTLPAASILAWKSVLGNGHLSSLGTRDTHPY
ASLSRALQTQCCISSPSHLMSQQYRPYSFFTKLTADELWKGALAETGAGAKKGRGKRTKK
KKRKDLNRGQIIGEGRYGFLWPGLNVPLMKNGAVQTIAQRSKEEQEKVEADMIQQREEWD
RKKKMKVKRERGWSGNSWGGISLGPPDPGPCGETYEDFDTRILEVRNVFTMTAKEGRKKS
IRVLVAVGNGKGAAGFSIGKATDRMDAFRKAKNRAVHHLHYIERYEDHTIFHDISLRFKR
THIKMKKQPKGYGLRCHRAIITICRLIGIKDMYAKVSGSINMLSLTQGLFRGLSRQETHQ
QLADKKGLHVVEIREECGPLPIVVASPRGPLRKDPEPEDEVPDVKLDWEDVKTAQGMKRS
VWSNLKRAAT
Sequence of entity 12 (E), FASTA
>8CSP_12 28S ribosomal protein S6, mitochondrial (chains E)
MPRYELALILKAMQRPETAATLKRTIEALMDRGAIVRDLENLGERALPYRISAHSQQHNR
GGYFLVDFYAPTAAVESMVEHLSRDIDVIRGNIVKHPLTQELKECEGIVPVPLAEKLYST
KKRKK
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| GDP | Guanosine-5'-diphosphate | C10 H15 N5 O11 P2 | 1 |
| ATP | Adenosine-5'-triphosphate | C10 H16 N5 O13 P3 | 1 |
| ZN | Zinc ion | Zn | 1 |
| FES | FE2/S2 (inorganic) cluster | Fe2 S2 | 2 |
| MG | Magnesium ion | Mg | 28 |
| SAM | S-adenosylmethionine | C15 H22 N6 O5 S | 1 |
| SF4 | Iron/sulfur cluster | Fe4 S4 | 1 |
Water and common crystallization additives (K) are not listed.
Primary citation
Principles of mitoribosomal small subunit assembly in eukaryotes. Harper, N.J., Burnside, C., Klinge, S. Nature (2023) 614:175-181. DOI 10.1038/s41586-022-05621-0 · PubMed
Other PDB entries of the same protein (UniProt P82930 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7QI4 2.21 Å, Human mitochondrial ribosome at 2.2 A resolution (bound to partly built tRNAs and mRNA)
- 8CSS 2.36 Å, Human mitochondrial small subunit assembly intermediate (State D)
- 7P2E 2.4 Å, Human mitochondrial ribosome small subunit in complex with IF3, GMPPMP and streptomycin
- 8RRI 2.4 Å, Human mitochondrial ribosome in complex with antibiotic tigecycline
- 9OLF 2.46 Å, Membrane-associated human mitoribosome in complex with TACO1
- 9OJM 2.5 Å, Human mitochondrial 28S PIC with tRNA and mtIF2
- 8CSQ 2.54 Å, Human mitochondrial small subunit assembly intermediate (State B)
- 8CSR 2.54 Å, Human mitochondrial small subunit assembly intermediate (State C)
- 6ZM6 2.59 Å, Human mitochondrial ribosome in complex with mRNA, A/A tRNA and P/P tRNA
- 7QI5 2.63 Å, Human mitochondrial ribosome in complex with mRNA, A/A-, P/P- and E/E-tRNAs at 2.63 A…
- 9RU6 2.64 Å, Human mitoribosome bound to TACO1 (Translational activator of COX1), mRNA, A/A-, P/P-…
- 7PNX 2.76 Å, Assembly intermediate of human mitochondrial ribosome small subunit without mS37 in…
Browse structure collections
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