8DNZ: Cryo-EM structure of the human Sec61 complex inhibited by apratoxin F

Cryo-EM structure of the human Sec61 complex inhibited by apratoxin F. Determined by electron microscopy at 2.57 Å resolution. Released 2023.

Composition

This structure contains 4,337 atoms across 4 protein chains. Molecular weight: 70.79 kDa.

Primary citation

A common mechanism of Sec61 translocon inhibition by small molecules.. Itskanov, S., Wang, L., Junne, T. et al., Nat.Chem.Biol. (2023).

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Source: RCSB Protein Data Bank