Leveraging the Structure of DNAJA1 to Discover Novel Pancreatic Cancer Therapies. Determined by solution NMR. Released 9 Nov 2022.
Explore 8E2O in 3D Show helices and sheets RCSB PDB PDBe
8E2O contains 5 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 10-23 | 14 | |
| α-helix | 29-46 | 18 | |
| α-helix | 49-58 | 10 | |
| α-helix | 60-62 | 3 | |
| α-helix | 78-82 | 5 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Isoform 2 of DnaJ homolog subfamily A member 1 | A | protein | 107 | Homo sapiens | P31689 (AlphaFold model) |
>8E2O_1 Isoform 2 of DnaJ homolog subfamily A member 1 (chains A) MVKETTYYDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGEKFKQISQAYEVLSDAKK RELYDKGGEQAIKEGGAGGGFGSPMDIFDMFFGGGGRMQRERRGKNV
Leveraging the Structure of DNAJA1 to Discover Novel Potential Pancreatic Cancer Therapies. Roth, H.E., De Lima Leite, A., Palermo, N.Y. et al. Biomolecules (2022) 12. DOI 10.3390/biom12101391 · PubMed
Other PDB entries of the same protein (UniProt P31689 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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