8I9P: Brix domain-containing protein
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Mak16. Determined by electron microscopy at 3.0 Å resolution. Released 17 May 2023.
- Method
- Electron microscopy
- Resolution
- 3.0 Å
- Organism
- Chaetomium thermophilum
- Chains
- 33
- Atoms
- 80,799
- Mol. weight
- 2246.93 kDa
- Ligands
- ZN
- Released
- 17 May 2023
Explore 8I9P in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8I9P contains 300 α-helices and 216 β-strands across 31 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain CA: 7 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 36-40 | 5 | 2 |
| α-helix | 46-56 | 11 | |
| β-strand | 62-64 | 3 | 2 |
| α-helix | 76-83 | 8 | |
| β-strand | 88-95 | 8 | 2 |
| β-strand | 99-106 | 8 | 2 |
| β-strand | 112-117 | 6 | 2 |
| β-strand | 139-142 | 4 | 2 |
| α-helix | 144-146 | 3 | |
| α-helix | 150-163 | 14 | |
| β-strand | 178-184 | 7 | 2 |
| β-strand | 189-199 | 11 | 2 |
| α-helix | 200-202 | 3 | |
| β-strand | 228-233 | 6 | 2 |
| β-strand | 238-246 | 9 | 2 |
| β-strand | 254-257 | 4 | 2 |
| α-helix | 264-294 | 31 | |
| α-helix | 311-314 | 4 | |
Chain CB: 13 helices, 13 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 20-39 | 20 | |
| α-helix | 41-42 | 2 | |
| β-strand | 46-48 | 3 | 3 |
| α-helix | 53-58 | 6 | |
| β-strand | 61-67 | 7 | 4 |
| β-strand | 81-84 | 4 | 5 |
| β-strand | 97-100 | 4 | 6 |
| α-helix | 105-113 | 9 | |
| α-helix | 120-123 | 4 | |
| β-strand | 124-128 | 5 | 6 |
| α-helix | 130-136 | 7 | |
| α-helix | 140-149 | 10 | |
| β-strand | 152-156 | 5 | 6 |
| α-helix | 160-162 | 3 | |
| α-helix | 163-166 | 4 | |
| α-helix | 169-172 | 4 | |
| α-helix | 178-179 | 2 | |
| β-strand | 180-182 | 3 | 6 |
| α-helix | 217-228 | 12 | |
| β-strand | 230-233 | 4 | 5 |
| β-strand | 240-247 | 8 | 4 |
| α-helix | 252-270 | 19 | |
| β-strand | 280 | 1 | 7 |
| β-strand | 281-284 | 4 | 4 |
| β-strand | 290-291 | 2 | 4 |
| β-strand | 294 | 1 | 7 |
Chain Cc: 13 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 19-34 | 16 | |
| α-helix | 36-40 | 5 | |
| α-helix | 44-59 | 16 | |
| α-helix | 64-76 | 13 | |
| α-helix | 77-80 | 4 | |
| α-helix | 83-85 | 3 | |
| α-helix | 86-99 | 14 | |
| α-helix | 109-126 | 18 | |
| β-strand | 128 | 1 | 11 |
| β-strand | 150 | 1 | 11 |
| α-helix | 152-164 | 13 | |
| β-strand | 172-175 | 4 | 12 |
| β-strand | 185-188 | 4 | 12 |
| α-helix | 189-190 | 2 | |
| α-helix | 191-208 | 18 | |
| α-helix | 216-234 | 19 | |
| α-helix | 239-249 | 11 | |
Chain CC: 15 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 123-125 | 3 | |
| β-strand | 137-140 | 4 | 9 |
| β-strand | 148-151 | 4 | 9 |
| α-helix | 152-155 | 4 | |
| α-helix | 157-159 | 3 | |
| β-strand | 185 | 1 | 10 |
| β-strand | 196 | 1 | 10 |
| α-helix | 233-244 | 12 | |
| α-helix | 256-259 | 4 | |
| α-helix | 275-277 | 3 | |
| α-helix | 278-280 | 3 | |
| α-helix | 285-299 | 15 | |
| α-helix | 309-315 | 7 | |
| α-helix | 334-336 | 3 | |
| α-helix | 341-348 | 8 | |
| α-helix | 350-352 | 3 | |
| α-helix | 361-363 | 3 | |
| α-helix | 364-372 | 9 | |
| α-helix | 399-412 | 14 | |
Chain Cd: 14 helices, 14 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 14-16 | 3 | |
| α-helix | 21-52 | 32 | |
| α-helix | 56-63 | 8 | |
| α-helix | 65-67 | 3 | |
| α-helix | 89-97 | 9 | |
| α-helix | 181-186 | 6 | |
| β-strand | 201-205 | 5 | 15 |
| α-helix | 212-221 | 10 | |
| β-strand | 225-227 | 3 | 15 |
| α-helix | 241-250 | 10 | |
| β-strand | 255-262 | 8 | 15 |
| β-strand | 265-273 | 9 | 15 |
| α-helix | 279-281 | 3 | |
| β-strand | 284-288 | 5 | 15 |
| β-strand | 293 | 1 | 16 |
| α-helix | 308-309 | 2 | |
| β-strand | 310-314 | 5 | 17 |
| α-helix | 319-330 | 12 | |
| β-strand | 342-349 | 8 | 17 |
| β-strand | 352-364 | 13 | 17 |
| α-helix | 365-366 | 2 | |
| α-helix | 370-374 | 5 | |
| β-strand | 386-392 | 7 | 17 |
| β-strand | 396 | 1 | 16 |
| β-strand | 397-399 | 3 | 17 |
| β-strand | 401-405 | 5 | 15 |
| β-strand | 419-422 | 4 | 15 |
| α-helix | 425-428 | 4 | |
Chain Ce: 9 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 3-12 | 10 | |
| β-strand | 18-20 | 3 | 20 |
| β-strand | 26-28 | 3 | 20 |
| β-strand | 50-55 | 6 | 21 |
| β-strand | 61-66 | 6 | 21 |
| α-helix | 68-70 | 3 | |
| α-helix | 74-76 | 3 | |
| β-strand | 78-82 | 5 | 21 |
| α-helix | 83-84 | 2 | |
| α-helix | 87-97 | 11 | |
| α-helix | 103-133 | 31 | |
| β-strand | 136-139 | 4 | 65 |
| α-helix | 143-160 | 18 | |
| α-helix | 162-175 | 14 | |
| α-helix | 188-194 | 7 | |
Chain CE: 27 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 112 | 1 | 13 |
| α-helix | 120-129 | 10 | |
| β-strand | 133 | 1 | 13 |
| α-helix | 136-146 | 11 | |
| β-strand | 151-153 | 3 | 14 |
| α-helix | 161-175 | 15 | |
| α-helix | 180-182 | 3 | |
| β-strand | 186-189 | 4 | 14 |
| α-helix | 193-206 | 14 | |
| β-strand | 214-217 | 4 | 14 |
| α-helix | 223-232 | 10 | |
| β-strand | 236-239 | 4 | 14 |
| α-helix | 241-250 | 10 | |
| β-strand | 260-263 | 4 | 14 |
| α-helix | 266-272 | 7 | |
| α-helix | 275-284 | 10 | |
| β-strand | 291-295 | 5 | 14 |
| α-helix | 301-310 | 10 | |
| β-strand | 317-318 | 2 | 14 |
| β-strand | 334-338 | 5 | 3 |
| α-helix | 341-343 | 3 | |
| α-helix | 344-354 | 11 | |
| β-strand | 359-364 | 6 | 3 |
| α-helix | 367-379 | 13 | |
| β-strand | 385-387 | 3 | 3 |
| α-helix | 393-404 | 12 | |
| β-strand | 409-414 | 6 | 3 |
| β-strand | 428-431 | 4 | 3 |
| α-helix | 434-435 | 2 | |
| α-helix | 438-440 | 3 | |
| α-helix | 441-445 | 5 | |
| α-helix | 446-450 | 5 | |
| β-strand | 457-462 | 6 | 3 |
| α-helix | 468-475 | 8 | |
| β-strand | 480-484 | 5 | 3 |
| α-helix | 487-489 | 3 | |
| α-helix | 494-503 | 10 | |
| α-helix | 505-523 | 19 | |
| α-helix | 533-535 | 3 | |
| α-helix | 538-545 | 8 | |
| α-helix | 550-552 | 3 | |
| α-helix | 571-572 | 2 | |
| α-helix | 575-578 | 4 | |
Chain CI: 7 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 187-192 | 6 | 18 |
| α-helix | 201-210 | 10 | |
| β-strand | 213-220 | 8 | 18 |
| β-strand | 227-235 | 9 | 18 |
| α-helix | 238-247 | 10 | |
| β-strand | 252-253 | 2 | 19 |
| β-strand | 256-257 | 2 | 19 |
| β-strand | 259-262 | 4 | 18 |
| α-helix | 263-264 | 2 | |
| α-helix | 265-267 | 3 | |
| α-helix | 285-294 | 10 | |
| α-helix | 296-297 | 2 | |
| α-helix | 301-321 | 21 | |
23 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| RNA (3341-mer) | C1 | RNA | 3341 | Chaetomium thermophilum | |
| RNA (306-mer) | C2 | RNA | 306 | Chaetomium thermophilum | |
| Brix domain-containing protein | CA | protein | 316 | Chaetomium thermophilum | G0RXZ3 (AlphaFold model) |
| Ribosome biogenesis protein C8F11.04 | CB | protein | 391 | Chaetomium thermophilum | G0S7X0 (AlphaFold model) |
| Ribosome biogenesis protein ERB1 | CC | protein | 801 | Chaetomium thermophilum | G0SCK6 (AlphaFold model) |
| RNA helicase | CE | protein | 598 | Chaetomium thermophilum | G0RYU9 (AlphaFold model) |
| Putative RNA-binding protein | CI | protein | 414 | Chaetomium thermophilum | G0S1H0 |
| Pescadillo homolog | CJ | protein | 679 | Chaetomium thermophilum | G0SHX6 |
| 60S ribosomal protein l7-like protein | CM, LF | protein | 249 | Chaetomium thermophilum | G0SFL0 |
| Nucleolar protein 16 | CR | protein | 237 | Chaetomium thermophilum | G0S832 |
| rRNA-processing protein EBP2 | CU | protein | 451 | Chaetomium thermophilum | G0SGC2 |
| 60S ribosomal protein L4-like protein | LC | protein | 365 | Chaetomium thermophilum | G0SFC3 |
20 more molecules are not listed.
Sequence of entity 1 (C1), FASTA
>8I9P_1 RNA (3341-MER) (chains C1)
GGUUGACCUCGGAUCAGGUAGGAGGACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGGA
AAAGAAACCAACAGGGAUUGCCCUAGUAACGGCGAGUGAAGCGGCAACAGCUCAAAUUUG
AAAGCUGGCUUCGGCCCGCGUUGUAAUUUGGAGAGGAUGCUUUGGGCGAGGCUCCUUCUG
AGUUCCCUGGAACGGGACGCCACAGAGGGUGAGAGCCCCGUAUAGUUGGAAGCCAAGCCU
GUGUAAAGCUCCUUCGACGAGUCGAGUAGUUUGGGAAUGCUGCUCAAAAUGGGAGGUAAA
UUUCUUCUAAAGCUAAAUACCGGCCAGAGACCGAUAGCGCACAAGUAGAGUGAUCGAAAG
AUGAAAAGCACUUUGAAAAGAGGGUUAAAUAGCACGUGAAAUUGUUGAAAGGGAAGCGCU
UGUGACCAGACUUGCGCCCGGCGGAUCAUCCGGUGUUCUCACCGGUGCACUCCGCCGGGC
UCAGGCCAGCAUCGGUUCUGGCGGGGGGAUAAAGGCCCAGGGAAUGUGGCUCCUCCGGGA
GUGUUAUAGCCCUGGGUGUAAUACCCUCGCCGGGACCGAGGACCGCGCUCUGCAAGGAUG
CUGGCGUAAUGGUCACCAGCGACCCGUCUUGAAACACGGACCAAGGAGUCAAGGUUUUGC
GCGAGUGUUUGGGUGUAAAACCCGCACGCGUAAUGAAAGUGAACGUAGGUGAGAGCUUCG
GCGCAUCAUCGACCGAUCCUGAUGUAUUCGGAUGGAUUUGAGUAGGAGCGUUAAGCCUUG
GACCCGAAAGAUGGUGAACUAUGCUUGGAUAGGGUGAAGCCAGAGGAAACUCUGGUGGAG
GCUCGCAGCGGUUCUGACGUGCAAAUCGAUCGUCAAAUCUGAGCAUGGGGGCGAAAGACU
AAUCGAACCAUCUAGUAGCUGGUUACCGCCGAAGUUUCCCUCAGGAUAGCAGUGUCGACC
UUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGGGACUCGGGGGCGAUUUUUAGCCUUCAUC
CAUUCUCAAACUUUAAAUAUGUAAGAAGCCCUUGUUACUUAACUGAACGUGGGCAUUCGA
AUGUAUCGACACUAGUGGGCCAUUUUUGGUAAGCAGAACUGGCGAUGCGGGAUGAACCGA
ACGCGGGGUUAAGGUGCCGGAGUGGACGCUCAUCAGACACCACAAAAGGCGUUAGUACAU
CUUGACAGCAGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAAGGACUGUGUAACAACUCA
CCUGCCGAAUGUACUAGCCCUGAAAAUGGAUGGCGCUCAAGCGUCCCACCCAUACCCCGC
CCUCAGGGUAGAAACGAUGCCCUGAGGAGUAGGCGGCCGUGGAGGUCAGUGACGAAGCCU
AGGGCGUGAGCCCGGGUCGAACGGCCUCUAGUGCAGAUCUUGGUGGUAGUAGCAAAUACU
UCAAUGAGAACUUGAAGGACCGAAGUGGGGAAAGGUUCCAUGUGAACAGCGGUUGGACAU
GGGUUAGUCGAUCCUAAGCCAUAGGGAAGUUCCGUUUCAAAGGGGCACUCGUGCCCCGUG
UGGCGAAAGGGAAGCCGGUUAAUAUUCCGGCACCUGGAUGUGGGUUUUGCGCGGCAACGC
AACUGAACGCGGAGACGACGGCGGGGGCCCCGGGCAGAGUUCUCUUUUCUUCUUAACGGU
CUAUCACCCUGGAAACAGUUUGUCUGGAGAUAGGGUUUAAUGGCCGGAAGAGCCCGACAC
UUCUGUCGGGUCCGGUGCGCUCUCGACGUCCCUUGAAAAUCCGCGGGAGGGAAUAAUUCU
CACGCCAGGUCGUACUCAUAACCGCAGCAGGUCCCCAAGGUGAACAGCCUCUGGUUGAUA
GAACAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGUAACUUCGGGAAAAGGAUUGGC
UCUAAGGGUUGGGCACGUUGGGCUUUGGGCGGACGCCCUGGGAGCAGAGGGCCUCUAGCC
GGGCAACCGGCCGGCGGCCCUCAGCACCCGGGGUUGAAGCCCUUAGCAGGCUUCGGCCGU
CCGGCGUGCGGUUAACAACCAACUUAGAACUGGUACGGACAGGGGGAAUCUGACUGUCUA
AUUAAAACAUAGCAUUGCGAUGGCCAGAAAGUGGUGUUGACGCAAUGUGAUUUCUGCCCA
GUGCUCUGAAUGUCAAAGUGAAGAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAACU
AUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGAU
UAACGAGAUUCCCACUGUCCCUAUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGGC
UUGGCAAAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUGA
AAAGACAUAGGAGGUGUAGAAUAGGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACUCC
UAUUGUUUUUUUACUUAUUCAAUGAAGCGGGGCUGGACUUGCGUCCAACUUCUGGAGUUA
AGGUCCUUCGCGGGCCGACCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGGC
GGCACAUCUGUUAAACCAUAACGCAGGUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAUC
UCCAGUAGAACAAAAGGGUAAAAGUCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAACC
AUGAAAGUGUGGCCUAUCGAUCCUUUAGUCCCUCGAAAUUUGAGGCUAGAGGUGCCAGAA
AAGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUUU
GAUCCUUCGAUGUCGGCUCUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUUG
UUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUA
CCCUACUGAUGAACUCGUCGCAAUGGUAAUUCAGCUUAGUACGAGAGGAACCGCUGAUUC
AGAUAAUUGGUUUUUGCGGUUGUCCGACCGGGCAGUGCCGCGAAGCUACCAUCUGCUGGA
UAAUGGCUGAACGCCUCUAAGUCAGAAUCCAUGCCAGAACGCGACGAUACUACCCGCACG
UUGUAGACGUAUAAGAAUAGGCUCCGGCCUCGUAUCCUAGCAGGCGAUUCCUCCGCCGGC
CUCGAAGUGGCCGUCGGUAAUUCGCGUAUUGCAAUUUAGACACGCGCGGGAUCAAAUCCU
UUGCAGACGACUUAGAUGUGCGAAAGGGUCCUGUAAGCAGUAGAGUAGCCUUGUUGUUAC
GAUCUGCUGAGGGUAAGCCCUCCUUCGCCUAGAUUUCCCAG
Sequence of entity 2 (C2), FASTA
>8I9P_2 RNA (306-MER) (chains C2)
AAACUUUCAACAACGGAUCUCUUGGUUCUGGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
AAGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCG
CCGGUAUUCCGGCGGGCAUGCCUGUUCGAGCGUCAUUUCAACCAUCAAGCCCUGGGCUUG
UGUUGGGGACCCGCGGCUGCUCGCGGGCCCUGAAAAGCAGUGGCGGGCUCGCUAGUCACA
CCGAGCGUAGUAGAACUUCUAUUCGAUCUCGCUCAGGGCGUGCGGCGGGUGCCAGCCGUA
AAACCC
Sequence of entity 3 (CA), FASTA
>8I9P_3 Brix domain-containing protein (chains CA)
MAAVYKTIAKVTGSKEDKDKEDRSNIIAERKNKQRVLVLSSRGVTYRHRHLLNDLASMLP
HGRKDAKFDTKSRLYELCELAELYNCNNVLFFEARKGKDLYMWFSKVPNGPTVKFYAQNL
HTMEELHFQGNCLKGSRPILSFDAAFEQEPYLKVIKELFLHTFGVPQGHKKSKPFIDHVL
SFSVADGKIWVRNYEIREVEKVKGEADKREEGETEKPKAAKPGSKDTDINLIEIGPRFVL
TPIIIQEGSFGGPILYENKRFISPNKIRAELRKAKAARHHARMEQQRDLLARKRQLGLDE
STPKKKDDLDTRELFA
Sequence of entity 4 (CB), FASTA
>8I9P_4 Ribosome biogenesis protein C8F11.04 (chains CB)
MAPSTAVAKKETDAVIPVDPDQTLKACKALLAHIKKAAAAPRPDGKQNLLADEESTVAET
PIWLTLTTKKHIHDSHRLQPGKIILPHPLNTSEEISVCLITADPQRFYKNAVADEFPEDL
RAKIGRVIDISHLKAKFKAYEAQRKLFSEHDVFLADTRIINRLPKALGKTFYKTTTKRPI
PVVLMAQREKVNGKRVPAPKGKKEKRDPLENANARPIPEIVAEIRKAIGAALVHLSPSTN
TAIKVGYANWEPEKLAANIETVIRELVERFVPQKWQNVRNFYVKGPETAALPIYQTDELW
LDESKVVPDGQEPARALPGKREKANIGKKRKPLEDASQPALEETGKDERPKKKAKKTLPE
SNDDKLDKAIAERKEQLKKQKAAAKKVAADI
Sequence of entity 5 (CC), FASTA
>8I9P_5 Ribosome biogenesis protein ERB1 (chains CC)
MGSKIVEKKRKSRDSDSESDNELGDGLFDGVLSQSEDEEDYIPSSEVDEDDDDDADESAS
EDSDDSNDSEDDEVEEDDEALLSDEIPSEGESEKDQDLAESKESKQDQDKEPSEPEILEP
FVDPPRKEDEELEDRNYRIEKDANGGIRYVYDEIDPVYDSDDTDYNVPVNTIGNIPLSFY
DSYPHIGYDINGKKIMRPATGDALQNLLDSIEVPEGWTGLTDPNTGKPLNLSRDELELIR
KVQQGLIPDDVEDPYPDTVEWFTSVEEKMPLSAAPEPKRRFIPSKNEAKQIMKLVRAIRE
GRILPYKPPEEREREELEKEEEFYDLWQNEEPQPPNPMHIPAPKLPPPGYDLSYNPPPEY
LPTKEEREEWEKMDPEDREKDYLPTKYDSLRKVPAWGNFVKERFERCMDLYLAPRVRKNR
LNIDPNSLLPKLPSPDELKPFPTVQQTIFRGHEGRVRSVAIDPTGVALATGGDDGTVRVW
ELLTGRQVWSVKLNGDEAVNTVRWRPTKDTFILAAAAGEDIFLMIPTHPSVTPALDQASR
DILNAGFGHATNGKQQANLPPGKEPPGKWARPGTRLEDEGVLLRITVRSTIKAISWHRRG
DHFATVSPSGQRSSVAIHTLSKHLTQIPFRKLNGLAQTASFHPLRPLFFVATQRSIRCYD
LQKLELVKIVQPGAKWISSFDVHPGGDNLVVGSYDKRLLWHDLDLSNRPYKTMRFHTEAI
RAVRFHKGGLPLFADASDDGSLQIFHGKVPNDQLENPTIVPVKMLKGHKVVNKLGVLDID
WHPREPWCVSAGADGTARLWM
Sequence of entity 6 (CE), FASTA
>8I9P_6 RNA helicase (chains CE)
MASESSKKRKFKDSKGPKPDEAVAKPSKFKKLKRDPTPEERETSDSESGNSDGQHEPDQV
DSDGEDAVSDDGSFDEKVAHQDEDGSRPENGTDLEDVPKNDNLLPPPTNAQEFSELNLSE
KTTKAIAEMGFTKMTEIQRRAIPPALAGKDVLGAAKTGSGKTLAFLIPAVEMLSSLRFKP
RNGTGAIVVTPTRELALQIFGVARELMKYHSQTYGVVIGGANRRAEAEKLGKGVNLLIAT
PGRLLDHLQNTPFVFKNLKSLIIDEADRILEIGFEDEMRQIVKILPKEDRQTMLFSATQT
TKVEDLARISLRPGPLYINVDEEKKYSTVEGLEQGYVVVEADKRFLLLFSFLKKMAKKKI
IVFFSSCNSVKYYSELLQYIDLPVLDLHGKQKQQKRTNTFFEFCNAKSGTLICTDVAARG
LDIPQVDWIVQFDPPDDPRDYIHRVGRTARGNNGKGRSLLFLQPCELGFLAHLKAAKVPV
VEYDFPKNKILNVQSQLEKLISTNYYLNQSAKEGYRSYIHAYASHSLRSVFDVHKLDLVK
VAKSFGFSTPPRVDITLSASLSRDKKPQGRRAYGSQPRQGGRYKKVGDIPDPQPNTFG
Sequence of entity 7 (CI), FASTA
>8I9P_7 Putative RNA-binding protein (chains CI)
MAAELRKKKSKSAVADADAAISKKEKATKVTKATPKAEKRKAPEEASPVAIKKQKADKDA
VVKKAAVAAEDKIAEKPVKSVLKKETSAKAKEAAKPKKKQEKVEEEEEEALENADAAFGS
DEESELDEQTKALMDTLDDGEESDEDESKQVSTFKKGQDVGKIPTPKKAPQKQTNGDSKP
AGDSQPGVMYIARLPHGFYEHELRGYFSQFGEITRLRVVRNKKTGASRHRAFIEFADAEV
ADIAARTMDKYLLFGHILTCKIVPPAQVHPDLFKGANRRFKVVPWNKMAGRQLERPLSES
QWQVKVAKEEQRRAARAEKLKEMGYEFEAPALKVPKAKPVLENGEEEKKAIETAPAPAVE
EKESKEVAKRQAEEEVEEKAPAPKTKKVKEDKPAKEAATISAPKKGKKSKKTKS
Sequence of entity 8 (CJ), FASTA
>8I9P_8 Pescadillo homolog (chains CJ)
MGKAKKKGKSGAARNYMTRTQAVKKLQLSLPDFRKLCIWKGIYPREPRDRRKVNKSATAS
TTFYYTKDIQYLLHEPLLQKFREQKALEKKISRALGRGDVSNAARLERNANLPEKTGKPR
YTLNHIIRERYPTFQDALRDLDDCLSMLFLFANLPSTTAVPAKMIARCERLCHEFQHYLI
VTHSLRKSFLSIKGIYYQANIQGEDILWLVPYKFNQRIVGDVDFRIMGTFVEFYMTLLGF
VNYRLYTSIGLKYPPKFDQVKDDQGAELAAFSLEGLNLASQNGEQKAITNGEEHGPDPKV
QAEVDKLVAKLREEEQQANGDKTDEKGEENEGDDKPSDAIDKFEPVAPGGDVLPQPSYSS
SDPSQLFANFTFFLSRETPRQPLEFILRAFGCKRIGWDAVLGEGAFTTDESDPRITHQII
DRPVIRAAVSEDGDGEDNQTSQKLAPNGRYPGRIYVQPQWVWDSINDEELKPPELYAPGA
QLPPHLSPFVKPTQGQYDPTKPLEEQQTEAEALEAELEDAQAQQEGSDEESGSEVENDMS
VASDEEDEQEDDFGGFSDEDEEQSDEGSEEGDEEEDDDEEEEATLERQRELEAELAGKAV
SKGKPLDPKVKAKLEAKKALERKKKQEAEELERAKGMLSKKKRKLFEQMQYSNAKKNAED
AKLRAKRRRIEKEMAAKKA
Sequence of entity 9 (CM, LF), FASTA
>8I9P_9 60S ribosomal protein l7-like protein (chains CM, LF)
MSSTTVPTQNDILVPETLLKKRKSQEKARAERAAALEKRKQANKEKRQVIFKRAEKYVKE
YREQEREKIRLARIAKQQGSFHIPAEAKLVFVIRIKGINKIPPKPRKILQLLRLRQINNG
VFVKVTKATAEMIKIVEPWVAYGYPNLKSVRELIYKRGYGKVNGQRIPLTDNAIIEENLG
KYGIICIEDLIHEIFTVGPNFKQAANFLWPFKLSNPNGGFRPRKFKHFIEGGDLGNREEH
INALIRAMN
Sequence of entity 10 (CR), FASTA
>8I9P_10 Nucleolar protein 16 (chains CR)
MGRELQKRKRRSSRPTIRMPNRRKKALNPAGNNIIAKSWNKKETLSQNYTRFGLVAKLGK
ATGGTAPGNKALLKDLNDPLAIKSGDQGLIKVSEVKVERDEQGRIKRVVRDNNPLNDPLN
DLDSDSESDAVPQQQQQEQPVLNNHIRQHDLELENVAADVDDESKPEVLRALEREATRPV
EKTVRHQSEREREWLQRLVDKHGDDVAAMARDRKLNPYQQTASDIKRRLKKAGLLSA
Sequence of entity 11 (CU), FASTA
>8I9P_11 rRNA-processing protein EBP2 (chains CU)
MAKKGATQSPKAGSKPNSQTGDAQSKNQKADRRKSNEPVVEKVAEKEEQREEETEESEED
ESEDEQLQIRANGNNESDSEEDSDENSEDEDESDDDSGDEHPTHHIDFEAIDDSDSESEL
DSDEENDKKQDSNKAQNGMSEDKMDVDKDGEDKSGDEEDEEEEIDVEELEPEDEEDEEQI
AAGTRTRQTINNKEGLLTALRRIQLDINPKTTPFSFHQSVVASKRTEDSIPQIEDDLQRE
LAFMNQALEAARLGRSLLRKEGVPFTRPTDYFAEMVRTDATMEKVKQKLIEEATAKKAAA
EARKQRDLKKFGKAVQVQKQLERAKQKREALDKINQLKRKRAEGGSAALGATEADDPFDV
AVDNELSRDSKPKKRRADGDHPVPNPKRQKKNAKYGFGGKKRGSKSGDAISSGDLSGFSV
KRMKYGGGAGGGKKKANRPGKARRKAAAAKR
Sequence of entity 12 (LC), FASTA
>8I9P_12 60S ribosomal protein L4-like protein (chains LC)
MASRPTVTVFGADGKPTGATEVLPKVFSAPIRPDIVKHVHTGMAKNKRQPYAVSEKAGHQ
TSAESWGTGRAVARIPRVSGGGTHRAGQGAFGNMCRSGRMFAPTKIWRKWHVKINQGQKR
FATASALAASAVAPLLMARGHQVSTVPEVPLVVDSAAVAGDAVAKTAAAYKLLKAIGAGP
DVEKVKKSKKLRAGKGKMRGRRHRQRRGPLIVYSPEHDGKELVKGFRNIPGVETCPVDAL
NLLQLAPGGHLGRFIVWTSAAIKQLDAVYESKKGFFLPANIVSQADLSRLINSTEIQSVL
RAPKGEARTKRACVQKKNPLRNKQIMLRLNPYASTFAKEKLGEVKAEEGKPPKVPASFKE
LLHEA
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ZN | Zinc ion | Zn | 2 |
Primary citation
Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis. Lau, B., Huang, Z., Kellner, N. et al. EMBO Rep (2023) 24:e56910-e56910. DOI 10.15252/embr.202356910 · PubMed
Other PDB entries of the same protein (UniProt G0RXZ3 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 8I9Z 2.7 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Spb4
- 8IA0 2.7 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Puf6
- 8I9X 2.8 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-1
- 8I9R 3.1 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State 5S RNP
- 8I9V 3.1 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-2
- 8I9W 3.1 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Dbp10-3
- 8I9Y 3.1 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-2
- 8I9T 3.6 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-1
Browse structure collections
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