8IAH: Adducin 1
Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State I, Global map. Determined by electron microscopy at 3.6 Å resolution. Released 3 May 2023.
- Method
- Electron microscopy
- Resolution
- 3.6 Å
- Organism
- Sus scrofa
- Chains
- 36
- Atoms
- 74,320
- Mol. weight
- 3567.55 kDa
- Ligands
- ADP
- Released
- 3 May 2023
Explore 8IAH in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
8IAH contains 495 α-helices and 301 β-strands across 36 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 0: 4 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 33-40 | 8 | |
| α-helix | 43-55 | 13 | |
| α-helix | 57-63 | 7 | |
| α-helix | 65-82 | 18 | |
Chain 1: 16 helices, 9 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 105-107 | 3 | |
| α-helix | 113-124 | 12 | |
| α-helix | 133-135 | 3 | |
| α-helix | 140-158 | 19 | |
| β-strand | 169-172 | 4 | 1 |
| β-strand | 180-182 | 3 | 1 |
| α-helix | 189-191 | 3 | |
| α-helix | 197 | 1 | |
| β-strand | 198-200 | 3 | 1 |
| β-strand | 206 | 1 | 1 |
| β-strand | 212 | 1 | 2 |
| α-helix | 221-230 | 10 | |
| β-strand | 236-240 | 5 | 1 |
| α-helix | 243-249 | 7 | |
| α-helix | 260-263 | 4 | |
| β-strand | 268-271 | 4 | 1 |
| α-helix | 279-290 | 12 | |
| β-strand | 296-299 | 4 | 1 |
| β-strand | 303-308 | 6 | 1 |
| α-helix | 311-331 | 21 | |
| α-helix | 346-351 | 6 | |
| α-helix | 374-385 | 12 | |
| α-helix | 402-404 | 3 | |
| α-helix | 496-512 | 17 | |
| α-helix | 518-521 | 4 | |
Chain 2: 14 helices, 10 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 106-109 | 4 | |
| α-helix | 113-124 | 12 | |
| α-helix | 140-158 | 19 | |
| β-strand | 169-172 | 4 | 3 |
| β-strand | 180-182 | 3 | 3 |
| α-helix | 189-191 | 3 | |
| β-strand | 198-200 | 3 | 3 |
| β-strand | 206-208 | 3 | 3 |
| α-helix | 214-217 | 4 | |
| α-helix | 222-230 | 9 | |
| β-strand | 236-240 | 5 | 3 |
| α-helix | 243-250 | 8 | |
| β-strand | 251 | 1 | 4 |
| α-helix | 260-265 | 6 | |
| β-strand | 268-271 | 4 | 3 |
| α-helix | 280-290 | 11 | |
| β-strand | 296-299 | 4 | 3 |
| β-strand | 303-308 | 6 | 3 |
| α-helix | 311-335 | 25 | |
| α-helix | 338-340 | 3 | |
| β-strand | 341 | 1 | 5 |
| α-helix | 346-353 | 8 | |
| α-helix | 374-387 | 14 | |
| α-helix | 402-404 | 3 | |
Chain 3: 18 helices, 16 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 118-121 | 4 | |
| α-helix | 130-147 | 18 | |
| β-strand | 157-159 | 3 | 6 |
| β-strand | 162 | 1 | 7 |
| β-strand | 166 | 1 | 7 |
| β-strand | 168-170 | 3 | 6 |
| α-helix | 171-172 | 2 | |
| α-helix | 177-179 | 3 | |
| β-strand | 186-188 | 3 | 6 |
| β-strand | 194-196 | 3 | 6 |
| α-helix | 209-218 | 10 | |
| β-strand | 224-228 | 5 | 6 |
| α-helix | 231-238 | 8 | |
| β-strand | 239 | 1 | 5 |
| α-helix | 242-244 | 3 | |
| α-helix | 248-253 | 6 | |
| β-strand | 257-259 | 3 | 6 |
| α-helix | 268-278 | 11 | |
| β-strand | 284-287 | 4 | 6 |
| β-strand | 291-296 | 6 | 6 |
| α-helix | 299-323 | 25 | |
| α-helix | 327-329 | 3 | |
| α-helix | 334-337 | 4 | |
| α-helix | 362-374 | 13 | |
| α-helix | 381-383 | 3 | |
| β-strand | 389 | 1 | 2 |
| α-helix | 400-401 | 2 | |
| β-strand | 432-436 | 5 | 8 |
| β-strand | 441-443 | 3 | 9 |
| β-strand | 461-463 | 3 | 9 |
| α-helix | 467-469 | 3 | |
| β-strand | 475-479 | 5 | 8 |
| α-helix | 492-508 | 17 | |
| α-helix | 518-523 | 6 | |
Chain 4: 12 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 118-121 | 4 | |
| α-helix | 130-146 | 17 | |
| β-strand | 157-159 | 3 | 10 |
| β-strand | 162 | 1 | 11 |
| β-strand | 166 | 1 | 11 |
| β-strand | 168-170 | 3 | 10 |
| α-helix | 171-172 | 2 | |
| β-strand | 186-188 | 3 | 10 |
| β-strand | 194-196 | 3 | 10 |
| α-helix | 210-218 | 9 | |
| β-strand | 224-227 | 4 | 10 |
| α-helix | 231-237 | 7 | |
| α-helix | 248-253 | 6 | |
| β-strand | 257-259 | 3 | 10 |
| α-helix | 270-278 | 9 | |
| β-strand | 284-287 | 4 | 10 |
| β-strand | 292-296 | 5 | 10 |
| α-helix | 299-323 | 25 | |
| β-strand | 329 | 1 | 4 |
| α-helix | 334-337 | 4 | |
| α-helix | 362-375 | 14 | |
| α-helix | 381-383 | 3 | |
| α-helix | 399-401 | 3 | |
Chain 5: 7 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 41-44 | 4 | |
| α-helix | 120-122 | 3 | |
| α-helix | 144-145 | 2 | |
| α-helix | 165-170 | 6 | |
| α-helix | 178-180 | 3 | |
| α-helix | 184-185 | 2 | |
| α-helix | 198-212 | 15 | |
Chain 6: 10 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 41-44 | 4 | |
| α-helix | 52-54 | 3 | |
| α-helix | 119-122 | 4 | |
| α-helix | 125-127 | 3 | |
| α-helix | 140-142 | 3 | |
| α-helix | 144-145 | 2 | |
| α-helix | 163-171 | 9 | |
| α-helix | 178-180 | 3 | |
| α-helix | 184-185 | 2 | |
| α-helix | 198-212 | 15 | |
Chain 7: 7 helices, 0 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 41-44 | 4 | |
| α-helix | 52-55 | 4 | |
| α-helix | 59-61 | 3 | |
| α-helix | 144-145 | 2 | |
| α-helix | 162-171 | 10 | |
| α-helix | 178-180 | 3 | |
| α-helix | 198-212 | 15 | |
28 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| Adducin 1 | 0, 1, 2 | protein | 744 | Sus scrofa | A0A8D1Q0D0 (AlphaFold model) |
| Beta-adducin | 3, 4, 9 | protein | 724 | Sus scrofa | I3L5B0 (AlphaFold model) |
| Dematin actin binding protein | 5, 6, 7 | protein | 405 | Sus scrofa | F1RMC1 (AlphaFold model) |
| Spectrin alpha, erythrocytic 1 | 8 | protein | 2417 | Sus scrofa | A0A8D1R4Y3 |
| Actin, cytoplasmic 1 | A, B, C, D, E, F, G, H, I, J, K, L | protein | 375 | Sus scrofa | Q6QAQ1 |
| Spectrin beta chain | M, N, O, P, Q, R, S, T | protein | 2148 | Sus scrofa | A0A480J001 |
| Tropomyosin-1.9 | U | protein | 248 | Sus scrofa | A0AA82WPI2 |
| Tropomyosin 3 | V, W, X | protein | 248 | Sus scrofa | Q6QA25 |
| Tropomodulin-1 | Y | protein | 359 | Sus scrofa | A0A4X1UDZ5 |
| SH3 domain-binding glutamic acid-rich-like protein | Z | protein | 107 | Sus scrofa | A0A8W4FER1 |
Sequence of entity 1 (0, 1, 2), FASTA
>8IAH_1 Adducin 1 (chains 0, 1, 2)
MNGDTRAAVVTSPPPTTAPHKERYFDRVDENNPEYLRERNMAPDLRQDFNMMEQKKRVSM
ILQSPAFCEELESMIQEQFKKGKNPTGLLALQQIADFMTTNVPNVYPAAPQGGMAALNMS
LGMVTPVNDLRGSDSIAYDKGEKLLRCKLAALYRLADLFGWSHLIYNHITTRVSSEQEHF
LIVPFGLLYSEVTASSLVKINLQGDVVDRGSTNLGVNQAGFTLHSAVYAARPDVKCVVHI
HTPAGAAVSAMKCGLLPISPEALSLGEVAYHDYHGILVDEEEKVLIQKNLGPKSKVLILR
NHGLVSVGESVEEAFYYIHNLVVACEIQVRTLASAGGPDNLVLLDPGKYKAKSRPPTSPA
GEGSGSPPAWQIGEQEFEALMRMLDNLGYRTGYPYRYPALREKSKKYSDVEVPASVTGYS
VASDGDSGTGSPLRHSFQKQQREKTRWLNSGRGDDASEEGQAGSSPKSKTKWTKEDGHRA
SASAVPNLFVPLNTNPKEVQEMRNKIREQNLQDIKTAGPQSQVLCGVVMDRSLVQGELVT
ASKAIIEKEYQPHVVVSTTGPNPFNTLTDRELEEYRREVERKQKGPEETLDERSDQKEDS
PPEPPAAPHTPPSTPVKLEEDLPQEPLSGDDSEAATFRPTLPDLPPDEPSEVLGFPTLEE
EEEEEEVGALCEAGRPPSPARPAAEASPEPAAAQAAEEPASPAAEEGAAADPGSDGSPGK
SPSKKKKKFRTPSFLKKSKKRSDS
Sequence of entity 2 (3, 4, 9), FASTA
>8IAH_2 Beta-adducin (chains 3, 4, 9)
MSEETVPEAASPPPAQGRQYFDRFSEEDPEYLRLRNRAADLRQDFNLMEQKKRVTMILQS
PSFREELEGLIQEQMKKGNNSSNIWALRQIADFMASTSHAVFPTSSMNFSMMTPINDLHT
ADSLNLAKGERLMRCKISSVYRLLDLYGWAQLSDTYVTLRVSKEQDHFLISPKGVSCSEV
TASSLIKVNILGEVVEKGSSCFPVDTTGFCLHSAIYAARPDVRCIIHLHTPATAAVSAMK
WGLLPVSHNALLVGDMAYFDFNGEMEQEADRINLQKCLGPTCKILVLRNHGVVALGDTVE
EAFYKVFHLQAACEIQVSALSSAGGVENLILLEQEKHRPHEVGSVQWAGSTFGPMQKSRL
GEHEFEALMRMLDNLGYRTGYPYRYPLVQEKTKHKSEVEIPATVTAFVFEEDGAPVPALR
QHAQKQQKEKTRWLNTPNTYLRVNVADEVQRSMGSPRPKTTWMKADEVEKSSSGMPIRIE
NPNQFVPLYTDPQEVLDMRNKIREQNRQDVKSAGPQSQLLASVIAEKSRSPSTESQLMSQ
GQADTKDESEETVPNPFSQLTDQELEEYKKEVERKKLELDGEKEPAVEEPGSPGKSAPAS
PAQSPAKSETKSPVGSPSKSVDEEAQKTEPSKPTTEPETTQPEGVVVNGREDEPTAEEIL
SKGLSQMTTHADTDVDTSKDKTESVTSGPMSPEGSPSKSPSKKKKKFRTPSFLKKSKKKE
KVES
Sequence of entity 3 (5, 6, 7), FASTA
>8IAH_3 Dematin actin binding protein (chains 5, 6, 7)
MERLQKQPLTSPGSVSSSRGSSVPGSPSSIVAKMDNQVLGYKDLAAIPKDKAILDIERPD
LMIYEPHFTYSLLEHVELPRSRERSLSPKSTSPPPSPEVWAESRSPGTFPQASAPRTTGT
PRTSLPHFHHPETTRPDSNIYKKPPIYKQREPTGGSPQSKHLIEDLIIESSKFPAAQPPD
PNQPAKIETDYWPCPPSLAVVETEWRKRKASRRGAEEEEEEEDDDSGEEMKALRERQREE
LSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSLQAGTSKSSSLPAYGRTTLSR
LQSTDFSPSGSETESPGLQNGEGQRGRMDRGTSLPCVLEQKIYPYEMLVVTNKGRTKLPP
GVDRMRLERHLSAEDFSRVFSMSPEEFGKLALWKRNELKKKASLF
Sequence of entity 4 (8), FASTA
>8IAH_4 Spectrin alpha, erythrocytic 1 (chains 8)
MNAGNWSQAMDSGGPKVLETAEEIQERRQEVLSRYGKFKEQVAERGQKLEDSYHYQVFKR
DADDLKKWILEKLKIAEDKSYEDPTNIQGKYQKHESFETEVQAKSRVIPELEEIRRVRFT
EGHVAHEDTKVLLEELHTLWNRLLEWTQQKGSLLLQALKLQQYLQECADILEWIGDKEAI
VTSEELGEDWERTEVLHKKFEEFQADLEIRRGRVNGVNQYADECVEENHPKLPLIQSRRE
EVNEAWERLNKLASQRQKSLSSVADLQRFKRDVTEAIQWIKEKEPQLTSEDYGKDLFTSE
ALFHSHKGLERNLAVMDDKVKELCAKADKLKLSHPSDADQIQQMKEDLVSNWEHIRTLAT
RRYEKLQASYWYQRFLSDYDELSGWMKEKTALINADELPTDVAGGEALLDRHQQHKHEID
SYDDRFQSAHETGQALLDANHEASDEVMEKMNILVHTRAALLELWNRRQQQYEQCLNLHL
FYRDSEQVDSWMSRQEAFLENEDLGNSLGSVEALLQKHDDFEEAFTAQEEKITTLDETAT
KLIDDHHYDSKNIAAIRDELLARQDALRKRAATRRKLLEDSFLLQQLYQDSDDLKNWINK
KKKLADDEDYKDTQNLKSQVQKQQVFEEELAANKILLDNLKQTGQEMIENNHYASERVAA
RLSDIDSLWRELLEATAQKGTQLYEANRLLQFENNAEDLQRWLEEVKWQAFSEDYGKGLA
DIQNLRRKHQLLESAVAARQDQADTLKDLAAHFEEIGHPNAGELRARQESLVSRFEELKE
PLSFRKNKLNDQFMLLWICRDTEDEEAWIQETEPSAASTYLGKDLIAAKKFLSRHQVIQA
DIANHEPRIQEITWRGNKMVEEGHFAAEDVASRIKSLNENMESLQARAARRQNALEANVQ
FQQYLADLHEAEAWIREKEPIVDNTNYGADEEAAGALLKKHEAFLVDLKAFGNSIQALRD
QAEACQQQQAAPVEADAREERVMALYDFEARSPREVTMKKDDILILLSSINEDWWKVEAD
DHQGFVPANYVRKLAHDEFPMLPQRRREEPENISQRQEQIENQYHSLLDRAEERRRRLLQ
RYNEFLLAYEAGDMLDWIREKKAENTGVELDDVWELQKKFDEFQTDLKTNEPRLRDINKV
ADDLLFEGLLTPEGTQIQQELNARWGSLQRLAEEQRQLLGSAHAVQMFHRDADDTKEQIE
KKCQALSAADPGSDLFSVQALQRQHEGFERDLTPLGEKVNILGETANRLSESHPDATDDL
QRQRLELKEAWEDLLGHTEDRKENLQEALKFYLFLSQARDLQNWISGIGGMVSSQELAED
LTGTEILIERHQEQRDEIEAEAPTFQVLEDFGRDLISSGHRASPEIEEKLQTVRLERDEL
EKAWEQRKKMLDQCLELQLFRVDCDQAENWMVARENYLSSDDKGSLDSLGALMKKCDDLD
KAITTQDKKITELELFAERLIADDHYAQEEIAVRLQRILDRWKALKAQLIAERTKLGDSA
DLKQFYRDLEDLNEWISEMLPTACDESYKDTTNIQRKYLKHKTFENEVHGRTEEVEGVIN
LGNALVERRACDGNEETVKGQVEELEKEWNHLLERTADKGQKLNEASRQQRFNTGIRDFE
FWLSEAETLLSMKDQARDLASAGNLLKKHQLLETEMLARKDALKDLDTLATDLISSGTFN
TEQIVEKRDNVNKRFLNVEQLSAEHHEKLKEDYALFQFFQDLDNEEFWIEEKLVQVRSQD
YGRDLHGVQNLLKKHKRLEGELVAHEPAIQNVLDMAATLGDKTTVGREAIQERLDQFVQH
WEQLKELTKARGFQLGESLEYLEFMENAEEEEAWLSEQETMVAQGDSGDSLATTQSLLKK
LEALENDFAAHEIQVQNVCAQGRDILSKEESQHKEEIATKIEALNEKTPSLAKAIAAWKS
RLEDDHSFQQFNWKADVVETWIAEKETSLKTNGNGADLAAFLTLLAKQDTLDATLQSFQQ
ERLSEITDLKDQLVTAEHNQTKAIEERHAALLRRWEQLLEASEAHRQKLLEKQLPLQKAE
DLFMEFAHKASAFNNWCENVEEDLSEPVHCVSLDAIRQLQKDHEAFLSSLARAQSDFNYL
LELDQQIKALNVPSSPYTWLTVEALERIWKHLSDIIKEREQELEKEEARQVKNFEMCQEF
EQNASAFLNWILETRAYFLDGSLLKETGTLESQLEANKRKQKEIQAMKRQLTKIEDLGEK
LEEALVLDIKFSTIGLAQQWDQLFQLGVRRQHNLEQQIQIRDTPGVSEETLEEFKTTYRH
FDENLTGRLSHKDFRSCLRGLNYYLPMVEEGESEPKFEKFLDAVDPGRKGYVTQEDYTYF
LIDKESENIKSSDEIENSFQALAEGKAYITKEDMKQALTPEQVSFCASHMQQYVDPRGRS
HPAGYDYVGFINSYFGN
Sequence of entity 5 (A, B, C, D, E, F, G, H, I, J, K, L), FASTA
>8IAH_5 Actin, cytoplasmic 1 (chains A, B, C, D, E, F, G, H, I, J, K, L)
MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQS
KRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMT
QIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDL
AGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSY
ELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLS
GGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQ
EYDESGPSIVHRKCF
Sequence of entity 6 (M, N, O, P, Q, R, S, T), FASTA
>8IAH_6 Spectrin beta chain (chains M, N, O, P, Q, R, S, T)
MTSATEFENVGNQPPYSRINARWDAPDDELDNDNSSARLFERSRIKALADEREVVQKKTF
TKWVNSHLARVSCRITDLYKDLRDGRMLIKLLEVLSGEMLPKPTKGKMRIHCLENVDKAL
QFLKEQRVHLENMGSHDIVDGNHRLVLGLIWTIILRFQIQDIVVQTQEGRETRSAKDALL
LWCQMKTAGYPNVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHAFDV
AERQLGIIQLLDPEDVFTENPDEKSIITYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIET
EKMIEKYSGLASDLLTWIEQTITVLNSRKFANSLAGVQQQLQAFSTYRTVEKPPKFQEKG
NLEVLLFTIQSRMRANNQKVYTPHDGKLVSDINRAWESLEEAEYRRELALRSELIRQEKL
EQLARRFDRKAAMRETWLNENQRLVAQDNFGYDLAAVEAAKKKHEAIETDTAAYEERVRA
LEDLARELELENYHDQKRITARKDNILRLWNYLQELLQSRRQRLETTLALQQLFQDMLHS
IDWMDEIKAHLLSAEFGKHLLEAEDLLQKHKLMEADIAIQGDKVKAITAATLQFTEETGY
QPCDPQVIRDRVSHLEQCFAELSNTAAGRKAQLEQSKRLWKLFWEMDEAKSWIKEKEQIY
SSLGYGKDLTSVLILQRKHKAFEDELRRLDPHLDQIFQEAEDMVALKQFGYPKNEAWVKE
VSAQWDQLKEVPAQWNQLKELAASRKKNLQDTENFFQFQGDVDDLKAWLQDAHKLLSGED
VGQDEGATRALGKKHKDFLEELEESRGVMEHLEQQAQDFPERFRDSPDVTNRLQVLRDLY
QQVVAQADLRRQRLQDALDLYTVFGETDACELWMGEKEKWLAQMDIPDTLEDLEVVQHRF
DILDQEMKTLIAQIDGVNVAANSLVESNHPRSTEVKQYQDHLNTRWREFQTMVLARREAV
DSALRVHNYCVDCEETSKWIIDKTKVVESTKDLGQDLAGVMAIQRKLSGLERDVAAIQVR
VGALEQESHRLMESHREQEKDIGERQAYVEELWQGLQQALKGQEALLGKSSQLQAFLQDL
DAFEAWLSTAQKEVASKDMPESLPEAEQLLQQHAALKDDIDRHQENYQHVKASGEKVIHG
QTDPEYLLLGQRLEGLDKGWDALCRMWESRGHTLAQCLGFQEFQKDAKQAEAILSNQEYT
LAHLEPPDSLEAAEAGIRKFQDFFTTMENNRDKVLSPVDSGNKLVAEGNLYSDKIKEKVQ
QIEDRHKRNNEKAQEASVLLQDNLALQNFLQNCQELTLWINDKLLTSQDVSYDDARNLHN
KWLKHTAFEAELASQQGWLENIDAEGKQLMEEKPQFEALVSQRLEALHRLWDELQATTKE
IGQRLSAARSSDLRSQTHADLNKWIRAMEDQLRSDDLGKDLTSVNRMLAKLKRVEDQVNV
RKEELGELFAHMPSPGEEAEDEDLSIEKRFLDLLEPLGRRKKQLESSKAKLQISRDLEDE
TLWVEERLPLAQSTDYGANLQTVQLFMKKNQTLQNEILGHAPRVEDVLYRGHQLVEAAEI
DCQDIEERLGHLQNSWDTLQEAAAGRLQRLWDASEAQQYYLDAGEAEAWISEQELYVISD
EMPQDEEGAIVMLKRHLRQQRMVEEYERNIKQLAGRAQSLLAAGHPEGEQIIRLQGQVDK
HYAGLKDMAEDRKRKLENKYRQFQMEREADDLEQWILEKDLVASSPEMGQDFDHVTLLRD
KFRDFARETGAIGQERVDNMNALIEHLIDAGHEEAASIAERKDGLNEMWADVLELIDTRM
QLLAASYDRHRYFYTGNEILGLIDEKHRELPEDVGLDASTAESFHRVHTAFERELHQLGV
QVQQFQDVATRLQAAYAGEEADSIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFS
MVRDLLSWMETIIRQIETQERPRDVSSVELLMKYHQGIWAEMDTRSKNFSACLELGESLL
QRQHQASDEIREKLQQVVSKKKEIDEKWKARSDRLSMLLEVCQFSRDASVAEAWLIAQEP
YLSSRDFGHTVDSVEKLIKRHEAFEKSTASWEPRFAALEKPTTLELKERQTPERPKEDAG
PQEEEGETAGEAPRGPHRAATERTSPVSSLSHLSSSWESLLPEPAHPY
Sequence of entity 7 (U), FASTA
>8IAH_7 Tropomyosin-1.9 (chains U)
MAGSSSLEAVRRKIRSLQEQADAAEERAGTLQRELDYERKLRETAEADVASLNRRIQLVE
EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAE
DADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQ
KEDKYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ
TLLELNNM
Sequence of entity 8 (V, W, X), FASTA
>8IAH_8 Tropomyosin 3 (chains V, W, X)
MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQAEAEVASLNRRIQLVE
EELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAE
EADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQIRLMDQNLKCLSAAEEKYSQ
KEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDKLKCTKEEHLCTQRMLDQ
TLLDLNEM
Sequence of entity 9 (Y), FASTA
>8IAH_9 Tropomodulin-1 (chains Y)
MSYRRELEKYRDLDEDEILGALTEEELRTLENELDELDPDNALLPAGLRQKDQTTKAPTG
PFKREELLDHLEKQAKEFKDREDLVPYTGEKRGKVWVPKQKPMDPVLETVTLEPELEEAL
ANASDAELCDIAAILGMHTLMSNQQYYQALGSSSIVNKEGLNSVIKPTQYKPVPDEEPNA
TDVEETLERIKNNDPKLEEVNLNNIRNIPIPTLKAYAEALKENSYVKKFSIVGTRSNDPV
AFALAEMLKVNKVLKTLNVESNFISGAGILRLVEALPYNTSLVELKIDNQSQPLGNKVEM
EIVSMLEKNATLLKFGYHFTQQGPRLRASNAMMNNNDLVRKRRLADLTGPIIPKCRSGI
Sequence of entity 10 (Z), FASTA
>8IAH_10 SH3 domain-binding glutamic acid-rich-like protein (chains Z)
MVIRVFIASSSGFVAIKKKQQDVVRFLEANKIEFEEVDITMSEEQRQWMYKNIPPEKKPA
QGNPLPPQIFNGDRYCGDYDSFFESKESNTVFSFLGLKSQLASKAEP
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ADP | Adenosine-5'-diphosphate | C10 H15 N5 O10 P2 | 12 |
Primary citation
Structural basis of membrane skeleton organization in red blood cells. Li, N., Chen, S., Xu, K. et al. Cell (2023) 186:1912-1929.e18. DOI 10.1016/j.cell.2023.03.017 · PubMed
Other PDB entries of the same protein (UniProt A0A8D1Q0D0 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 8IAI 3.5 Å, Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State II,…
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MolViewer shows 8IAH directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.