human PHOX2B C-terminal domain including the polyA fragment at 278K. Determined by solution NMR. Released 13 Mar 2024.
Explore 8PTL in 3D Show helices and sheets RCSB PDB PDBe
8PTL contains 3 α-helices and 0 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
| Element | Residues | Length | Sheet |
|---|---|---|---|
| α-helix | 241-260 | 20 | |
| α-helix | 282-284 | 3 | |
| α-helix | 293-294 | 2 |
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|---|---|---|---|---|
| Paired mesoderm homeobox protein 2B | A | protein | 87 | Homo sapiens | Q99453 (AlphaFold model) |
>8PTL_1 Paired mesoderm homeobox protein 2B (chains A) GPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQGWAPGPGPITSIPDSL GGPFASVLSSLQRPNGAKAALVKSSMF
Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions. Anton, R., Trevino, M.A., Pantoja-Uceda, D. et al. Nat Commun (2024) 15:1925-1925. DOI 10.1038/s41467-024-46236-5 · PubMed
Other PDB entries of the same protein (UniProt Q99453 (AlphaFold model), which also has an AlphaFold model), best resolution first:
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