8PV2: Large ribosomal subunit protein uL10

Name: PDB 8PV2: Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1
Published: 2023-11-15
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: ribosome

Chaetomium thermophilum pre-60S State 10 - pre-5S rotation with Ytm1-Erb1. Determined by electron microscopy at 2.63 Å resolution. Released 15 Nov 2023.

Method: Electron microscopy
Resolution: 2.63 Å
Organism: Thermochaetoides thermophila DSM 1495
Chains: 57
Atoms: 155,881
Mol. weight: 3014.03 kDa
Ligands: GTP, MG, ZN
Released: 15 Nov 2023

Explore 8PV2 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

8PV2 contains 563 α-helices and 521 β-strands across 54 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain Cb: 10 helices, 3 β-strands

Element	Residues	Length	Sheet
α-helix	6-8	3
α-helix	12-14	3
α-helix	15-18	4
α-helix	19-27	9
α-helix	29-37	9
α-helix	41-43	3
α-helix	45-48	4
β-strand	51-52	2	81
β-strand	57-58	2	81
α-helix	62-69	8
α-helix	72-83	12
α-helix	88-95	8
β-strand	99-100	2	77

Chain CC: 16 helices, 32 β-strands

Element	Residues	Length	Sheet
α-helix	285-300	16
α-helix	309-315	7
α-helix	334-336	3
α-helix	341-348	8
β-strand	353	1	12
α-helix	358-360	3
α-helix	364-372	9
α-helix	374	1
α-helix	393-396	4
α-helix	399-411	13
α-helix	425-427	3
α-helix	430-431	2
β-strand	445-450	6	13
β-strand	456-461	6	14
β-strand	467-472	6	14
β-strand	476-481	6	14
β-strand	487-492	6	14
β-strand	499-504	6	15
β-strand	513-517	5	15
β-strand	520-524	5	15
α-helix	533-543	11
α-helix	545-547	3
β-strand	568-570	3	15
α-helix	574-579	6
β-strand	581-586	6	15
β-strand	593-596	4	16
β-strand	602-606	5	16
α-helix	611-613	3
β-strand	615-619	5	16
β-strand	624-626	3	16
β-strand	636-641	6	17
β-strand	647-652	6	17
β-strand	656-660	5	17
β-strand	665-670	6	17
β-strand	677-682	6	18
β-strand	688-693	6	18
β-strand	698-702	5	18
β-strand	711-713	3	18
β-strand	720-725	6	19
β-strand	732-737	6	19
β-strand	742-748	7	19
β-strand	758-765	8	19
α-helix	768-770	3
β-strand	771	1	20
β-strand	774	1	20
β-strand	776-781	6	13
β-strand	788-792	5	13
β-strand	796-800	5	13

Chain Cd: 30 helices, 16 β-strands

Element	Residues	Length	Sheet
α-helix	7-14	8
α-helix	16-17	2
α-helix	32-42	11
β-strand	47-48	2	88
β-strand	54-56	3	88
α-helix	57-58	2
α-helix	64-66	3
β-strand	68-69	2	58
α-helix	74-77	4
β-strand	81-83	3	62
α-helix	85-97	13
β-strand	104-108	5	89
α-helix	114-116	3
α-helix	119-122	4
α-helix	123-138	16
α-helix	141-144	4
α-helix	154-155	2
α-helix	161-184	24
β-strand	206-207	2	90
α-helix	208-211	4
α-helix	212-215	4
α-helix	220-232	13
β-strand	235-241	7	91
α-helix	245-248	4
α-helix	251-260	10
β-strand	265-271	7	91
α-helix	273-275	3
α-helix	278-288	11
β-strand	294-296	3	91
β-strand	298	1	92
β-strand	305	1	92
α-helix	307-320	14
β-strand	327-333	7	91
α-helix	339-347	9
β-strand	365-370	6	91
β-strand	373-377	5	91
α-helix	390-396	7
α-helix	401-403	3
α-helix	407-410	4
α-helix	411-417	7
α-helix	420-427	8
α-helix	435-446	12
β-strand	449	1	93
β-strand	455	1	93
α-helix	457-469	13
α-helix	477-481	5

Chain CD: 10 helices, 36 β-strands

Element	Residues	Length	Sheet
β-strand	14-20	7	23
β-strand	34-38	5	23
α-helix	43-50	8
β-strand	63-67	5	23
β-strand	70-71	2	23
α-helix	76-82	7
α-helix	90	1
β-strand	91-97	7	23
α-helix	98-102	5
β-strand	103-109	7	24
β-strand	114-120	7	25
α-helix	125-131	7
β-strand	145-150	6	25
β-strand	155-158	4	25
β-strand	164-167	4	25
β-strand	180-185	6	26
β-strand	190-195	6	26
β-strand	200-207	8	26
β-strand	213-221	9	26
β-strand	228-234	7	27
β-strand	239-244	6	27
β-strand	249-253	5	27
β-strand	285-287	3	26
β-strand	291-293	3	27
α-helix	299	1
β-strand	300-305	6	28
β-strand	312-317	6	28
β-strand	321-326	6	28
β-strand	331-337	7	28
β-strand	342-348	7	29
β-strand	357-362	6	29
β-strand	366-370	5	29
β-strand	382-385	4	29
β-strand	391-396	6	30
β-strand	404-408	5	30
β-strand	413-416	4	30
β-strand	422-423	2	29
α-helix	424-425	2
β-strand	433-435	3	29
β-strand	437-441	5	30
α-helix	444-449	6
α-helix	454-455	2
α-helix	456-458	3
β-strand	463-468	6	24
β-strand	473-477	5	24
β-strand	481-486	6	24

Chain Cf: 18 helices, 16 β-strands

Element	Residues	Length	Sheet
α-helix	10-19	10
α-helix	25-28	4
β-strand	30-35	6	95
α-helix	40-52	13
β-strand	57-64	8	95
α-helix	73-82	10
β-strand	86-91	6	95
β-strand	99-106	8	95
β-strand	109-118	10	95
α-helix	119	1
β-strand	124	1	96
α-helix	126-128	3
α-helix	132-134	3
β-strand	135	1	97
α-helix	138-140	3
β-strand	141-145	5	95
α-helix	147-149	3
α-helix	156-168	13
β-strand	175-177	3	98
α-helix	178-180	3
β-strand	183-188	6	95
β-strand	224-235	12	95
α-helix	242	1
β-strand	243-248	6	95
β-strand	252	1	96
β-strand	253-261	9	95
α-helix	262-264	3
α-helix	265-272	8
α-helix	275-277	3
α-helix	281-284	4
β-strand	287-289	3	89
β-strand	295-298	4	89
α-helix	309-312	4
α-helix	315-317	3

Chain CF: 19 helices, 16 β-strands

Element	Residues	Length	Sheet
α-helix	6-11	6
α-helix	20-33	14
β-strand	39-44	6	31
α-helix	53-59	7
β-strand	64-66	3	31
α-helix	70-77	8
α-helix	89-92	4
α-helix	93-95	3
β-strand	100-105	6	31
α-helix	109-118	10
β-strand	121-123	3	32
α-helix	124-126	3
α-helix	129	1
β-strand	130	1	33
α-helix	131	1
β-strand	135-137	3	34
α-helix	138	1
β-strand	140-141	2	35
β-strand	143	1	36
β-strand	156	1	36
α-helix	157-158	2
α-helix	159-161	3
α-helix	162-167	6
β-strand	172-175	4	35
β-strand	178-181	4	35
α-helix	190-191	2
β-strand	192-195	4	34
α-helix	199	1
β-strand	200	1	33
α-helix	201	1
α-helix	203-211	9
β-strand	217-219	3	32
β-strand	222-228	7	31
β-strand	233-236	4	31
α-helix	238-242	5

Chain Cg: 11 helices, 7 β-strands

Element	Residues	Length	Sheet
β-strand	22-24	3	95
β-strand	29-32	4	95
α-helix	44-68	25
β-strand	72-74	3	98
β-strand	79-82	4	98
α-helix	83-86	4
α-helix	95-97	3
α-helix	99-102	4
α-helix	104-112	9
α-helix	114-118	5
β-strand	126-128	3	103
β-strand	133-135	3	103
α-helix	143-145	3
β-strand	152-154	3	74
α-helix	157-162	6
α-helix	164	1
α-helix	169-171	3
α-helix	172-197	26

Chain Ch: 11 helices, 40 β-strands

Element	Residues	Length	Sheet
β-strand	36-42	7	105
β-strand	48	1	105
β-strand	53-56	4	105
α-helix	62-73	12
α-helix	77-79	3
β-strand	83-88	6	105
β-strand	95-96	2	105
α-helix	99-100	2
α-helix	103-110	8
α-helix	119	1
β-strand	120-126	7	105
α-helix	127-128	2
α-helix	131-135	5
β-strand	137-142	6	106
β-strand	149-154	6	107
β-strand	161-166	6	107
β-strand	170-175	6	107
β-strand	180-186	7	107
β-strand	192-197	6	108
β-strand	204-208	5	108
β-strand	213-217	5	108
β-strand	222-228	7	108
β-strand	235-240	6	109
α-helix	241-242	2
α-helix	243-245	3
β-strand	252-257	6	109
β-strand	261-266	6	109
β-strand	272-277	6	109
β-strand	283-288	6	110
β-strand	293-298	6	110
β-strand	303-307	5	110
β-strand	312-317	6	110
β-strand	324-329	6	111
α-helix	332-337	6
α-helix	350-365	16
β-strand	366-367	2	112
β-strand	370-371	2	112
β-strand	375-379	5	111
β-strand	384-387	4	111
β-strand	398-400	3	111
β-strand	407-412	6	113
β-strand	418-423	6	113
β-strand	428-432	5	113
β-strand	438-442	5	113
β-strand	449-454	6	114
β-strand	460-465	6	114
β-strand	470-474	5	114
β-strand	479-484	6	114
β-strand	491-496	6	106
β-strand	503-507	5	106
β-strand	512-516	5	106

46 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
26S rRNA	C1	RNA	3338	Thermochaetoides thermophila DSM 1495
5.8S rRNA	C2	RNA	156	Thermochaetoides thermophila DSM 1495
5S rRNA	C4	RNA	119	Thermochaetoides thermophila DSM 1495
Large ribosomal subunit protein uL10	CF	protein	270	Thermochaetoides thermophila DSM 1495	G0S616 (AlphaFold model)
Nucleolar GTP-binding protein 1	CH	protein	661	Thermochaetoides thermophila DSM 1495	G0S8F1 (AlphaFold model)
Ribosome biogenesis protein NSA2 homolog	CK	protein	261	Thermochaetoides thermophila DSM 1495	G0S081 (AlphaFold model)
Putative GTP binding protein	CL	protein	558	Thermochaetoides thermophila DSM 1495	G0SEW3 (AlphaFold model)
Eukaryotic translation initiation factor 6	CN	protein	246	Thermochaetoides thermophila DSM 1495	G0S683
DUF2423 domain-containing protein	CO	protein	120	Thermochaetoides thermophila DSM 1495	G0SHK0
Ribosome biogenesis protein RLP24	CQ	protein	225	Thermochaetoides thermophila DSM 1495	G0S497
Zinc finger domain-containing protein	Cb	protein	117	Thermochaetoides thermophila DSM 1495	G0SB32
Nucleolar GTP-binding protein 2	Cd	protein	627	Thermochaetoides thermophila DSM 1495	G0SBX1

44 more molecules are not listed.

Sequence of entity 1 (C1), FASTA

>8PV2_1 26S rRNA (chains C1)
AGGUUGACCUCGGAUCAGGUAGGAGGACCCGCUGAACUUAAGCAUAUCAAUAAGCGGAGG
AAAAGAAACCAACAGGGAUUGCCCUAGUAACGGCGAGUGAAGCGGCAACAGCUCAAAUUU
GAAAGCUGGCUUCGGCCCGCGUUGUAAUUUGGAGAGGAUGCUUUGGGCGAGGCUCCUUCU
GAGUUCCCUGGAACGGGACGCCACAGAGGGUGAGAGCCCCGUAUAGUUGGAAGCCAAGCC
UGUGUAAAGCUCCUUCGACGAGUCGAGUAGUUUGGGAAUGCUGCUCAAAAUGGGAGGUAA
AUUUCUUCUAAAGCUAAAUACCGGCCAGAGACCGAUAGCGCACAAGUAGAGUGAUCGAAA
GAUGAAAAGCACUUUGAAAAGAGGGUUAAAUAGCACGUGAAAUUGUUGAAAGGGAAGCGC
UUGUGACCAGACUUGCGCCCGGCGGAUCAUCCGGUGUUCUCACCGGUGCACUCCGCCGGG
CUCAGGCCAGCAUCGGUUCUGGCGGGGGGAUAAAGGCCCAGGGAAUGUGGCUCCUCCGGG
AGUGUUAUAGCCCUGGGUGUAAUACCCUCGCCGGGACCGAGGACCGCGCUCUGCAAGGAU
GCUGGCGUAAUGGUCACCAGCGACCCGUCUUGAAACACGGACCAAGGAGUCAAGGUUUUG
CGCGAGUGUUUGGGUGUAAAACCCGCACGCGUAAUGAAAGUGAACGUAGGUGAGAGCUUC
GGCGCAUCAUCGACCGAUCCUGAUGUAUUCGGAUGGAUUUGAGUAGGAGCGUUAAGCCUU
GGACCCGAAAGAUGGUGAACUAUGCUUGGAUAGGGUGAAGCCAGAGGAAACUCUGGUGGA
GGCUCGCAGCGGUUCUGACGUGCAAAUCGAUCGUCAAAUCUGAGCAUGGGGGCGAAAGAC
UAAUCGAACCAUCUAGUAGCUGGUUACCGCCGAAGUUUCCCUCAGGAUAGCAGUGUCGAC
CUUCAGUUUUAUGAGGUAAAGCGAAUGAUUAGGGACUCGGGGGCGAUUUUUAGCCUUCAU
CCAUUCUCAAACUUUAAAUAUGUAAGAAGCCCUUGUUACUUAACUGAACGUGGGCAUUCG
AAUGUAUCGACACUAGUGGGCCAUUUUUGGUAAGCAGAACUGGCGAUGCGGGAUGAACCG
AACGCGGGGUUAAGGUGCCGGAGUGGACGCUCAUCAGACACCACAAAAGGCGUUAGUACA
UCUUGACAGCAGGACGGUGGCCAUGGAAGUCGGAAUCCGCUAAGGACUGUGUAACAACUC
ACCUGCCGAAUGUACUAGCCCUGAAAAUGGAUGGCGCUCAAGCGUCCCACCCAUACCCCG
CCCUCAGGGUAGAAACGAUGCCCUGAGGAGUAGGCGGCCGUGGAGGUCAGUGACGAAGCC
UAGGGCGUGAGCCCGGGUCGAACGGCCUCUAGUGCAGAUCUUGGUGGUAGUAGCAAAUAC
UUCAAUGAGAACUUGAAGGACCGAAGUGGGGAAAGGUUCCAUGUGAACAGCGGUUGGACA
UGGGUUAGUCGAUCCUAAGCCAUAGGGAAGUUCCGUUUCAAAGGGGCACUCGUGCCCCGU
GUGGCGAAAGGGAAGCCGGUUAAUAUUCCGGCACCUGGAUGUGGGUUUUGCGCGGCAACG
CAACUGAACGCGGAGACGACGGCGGGGGCCCCGGGCAGAGUUCUCUUUUCUUCUUAACGG
UCUAUCACCCUGGAAACAGUUUGUCUGGAGAUAGGGUUUAAUGGCCGGAAGAGCCCGACA
CUUCUGUCGGGUCCGGUGCGCUCUCGACGUCCCUUGAAAAUCCGCGGGAGGGAAUAAUUC
UCACGCCAGGUCGUACUCAUAACCGCAGCAGGUCCCCAAGGUGAACAGCCUCUGGUUGAU
AGAACAAUGUAGAUAAGGGAAGUCGGCAAAAUAGAUCCGUAACUUCGGGAAAAGGAUUGG
CUCUAAGGGUUGGGCACGUUGGGCUUUGGGCGGACGCCCUGGGAGCAGAGGGCCUCUAGC
CGGGCAACCGGCCGGCGGCCCUCAGCACCCGGGGUUGAAGCCCUUAGCAGGCUUCGGCCG
UCCGGCGUGCGGUUAACAACCAACUUAGAACUGGUACGGACAGGGGGAAUCUGACUGUCU
AAUUAAAACAUAGCAUUGCGAUGGCCAGAAAGUGGUGUUGACGCAAUGUGAUUUCUGCCC
AGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAACCAAGCGCGGGUAAACGGCGGGAGUAAC
UAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAUGGA
UUAACGAGAUUCCCACUGUCCCUAUCUACUAUCUAGCGAAACCACAGCCAAGGGAACGGG
CUUGGCAAAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUUUGACAUUGUG
AAAAGACAUAGGAGGUGUAGAAUAGGUGGGAGCUUCGGCGCCAGUGAAAUACCACUACUC
CUAUUGUUUUUUUACUUAUUCAAUGAAGCGGGGCUGGACUUGCGUCCAACUUCUGGAGUU
AAGGUCCUUCGCGGGCCGACCCGGGUUGAAGACAUUGUCAGGUGGGGAGUUUGGCUGGGG
CGGCACAUCUGUUAAACCAUAACGCAGGUGUCCUAAGGGGGGCUCAUGGAGAACAGAAAU
CUCCAGUAGAACAAAAGGGUAAAAGUCCCCUUGAUUUUGAUUUUCAGUGUGAAUACAAAC
CAUGAAAGUGUGGCCUAUCGAUCCUUUAGUCCCUCGAAAUUUGAGGCUAGAGGUGCCAGA
AAAGUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUU
UGAUCCUUCGAUGUCGGCUCUUCCUAUCAUACCGAAGCAGAAUUCGGUAAGCGUUGGAUU
GUUCACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUU
ACCCUACUGAUGAACUCGUCGCAAUGGUAAUUCAGCUUAGUACGAGAGGAACCGCUGAUU
CAGAUAAUUGGUUUUUGCGGUUGUCCGACCGGGCAGUGCCGCGAAGCUACCAUCUGCUGG
AUAAUGGCUGAACGCCUCUAAGUCAGAAUCCAUGCCAGAACGCGACGAUACUACCCGCAC
GUUGUAGACGUAUAAGAAUAGGCUCCGGCCUCGUAUCCUAGCAGGCGAUUCCUCCGCCGG
CCUCGAAGUGGCCGUCGGUAAUUCGCGUAUUGCAAUUUAGACACGCGCGGGAUCAAAUCC
UUUGCAGACGACUUAGAUGUGCGAAAGGGUCCUGUAAGCAGUAGAGUAGCCUUGUUGUUA
CGAUCUGCUGAGGGUAAGCCCUCCUUCGCCUAGAUUUC

Sequence of entity 2 (C2), FASTA

>8PV2_2 5.8S rRNA (chains C2)
AAACUUUCAACAACGGAUCUCUUGGUUCUGGCAUCGAUGAAGAACGCAGCGAAAUGCGAU
AAGUAAUGUGAAUUGCAGAAUUCCGUGAAUCAUCGAAUCUUUGAACGCACAUUGCGCCCG
CCGGUAUUCCGGCGGGCAUGCCUGUUCGAGCGUCAU

Sequence of entity 3 (C4), FASTA

>8PV2_3 5S rRNA (chains C4)
ACGUACGACCAUACCCAGUGGAAAGCACGGCAUCCCGUCCGCUCUGCCCUAGUUAAGCCA
CUGAGGGCCCGGUUAGUAGUUGGGUCGGUGACGACCAGCGAAUCCCGGGUGUUGUACGU

Sequence of entity 4 (CF), FASTA

>8PV2_4 Large ribosomal subunit protein uL10 (chains CF)
MPKSKRARVYHLTQVNKKGREAKERLFSNIRETIPKYQHCFVFSVDNMRNNYLKDVRHEL
NDCRIFFGKTKLMARALGTTPEEEQADGLHRLTRYLTGTVGLLFTNRDPADIESYFSNLS
QVDFARAGTVAPRTVTVPPGIVYSTGGEVPPEHDVPVSHTLEPELRRLGMPVRMIKGKVC
LGDEKGEASEGYTICKEGEVLDSRQTRLLKLFSICLSEFKVSLLGYWSSASGEVTELEAG
KTRPKREGNRRQAMNGDEMDEDQSSDEDSD

Sequence of entity 5 (CH), FASTA

>8PV2_5 Nucleolar GTP-binding protein 1 (chains CH)
MTGWKDIPPVPTAQEFIDIVLSRTQRRLPTQIRPGFKISRIRAFYTRKVKFTQETCSEKF
GAIISSFPVLSDQHPFHRDLMNILYDADHFKVALGQISTAKNLIETISRDYVRLLKYAQS
LYQCKQLKRAALGRMATLIKRLKDPLIYLDQVRQHLARLPDINPTTRTLLVAGFPNVGKS
SFVRSVTRADTPVEPYAFTTKSLFVGHLDYKYLRYQVIDTPGILDHPLEEMNTIEMQSVT
ALAHLRAAVLYFMDISEQCGFSLKAQINLFKSIKPLFANKMVFIVLNKMDIKKFEELDPE
MQQEINDLTKSGEVEILRASCATQEGVQEVKNHVCERLLVERVSQKLKAGTHSNGNIGTR
LQEVMARIHVATPMDGTTRETFIPEAVKNLKKYDKNDPNRRVLARDIEEANGGAGVFNVD
LRKDWILENPEWKYDKIPEIFDGKNVYDYIDPDIDAKLQALEEEEERLEKEGFYDEDDDL
PDEEEEEILQKAEYIREQHALIRNEAKMRKSLKNRAIIPRKAVKKPLSQLEDHLDQLGVD
TEAIGLRARAQTAQSSRGRSLVRSRGTTADPDAMDIDDGAASAKERLARSRSRARSVAAT
NRLQDGVQGTTLRSKAERQAKLAQRKMNRMARQGEADRHIHASMPKHLFSGKRTIGKTDR
R

Sequence of entity 6 (CK), FASTA

>8PV2_6 Ribosome biogenesis protein NSA2 homolog (chains CK)
MPQNEYIERHRKLHGRRLDAEERARKKAAREGHKNSENAQNLRGLRAKLYAKQRHAQKIQ
MRKAIKQHEERNVKGRPAEKEPSDPIPSYLLDRANPTTAKALSSQIKNKRAEKAARFSVP
IPKVRGISEEEMFKVVKTGKKTHKKGWKRIVTKPTFVGPDFTRRPVKYERFIRPMGLRYK
KANVTHPTLNVTVQLPILSVKKNPSNPLYTQLGVLTKGTIIEVNVSDLGIVTASGKIAWG
RYAQITNNPENDGCVNAVLLV

Sequence of entity 7 (CL), FASTA

>8PV2_7 Putative GTP binding protein (chains CL)
MAGTINKPKKPTSKRKTTRLRAKISKRAAEKKRKERKLARKNPEWRSKLKKDPGIPNLFP
YKERLLQQIEEERIRRKEELLRKKELAKAAKTGADGDNKDDEQMQEDDEHMIREEELDLD
DAMDEDGSDVDESNPLAALVRSARKAAEEYEKELQSGSEMDEDDEDDSDDASDAGSDAGV
ITEVHGGATSRKAYDKVFKQVVEQADVILYVLDARDPEGTRSHDVEQAVMAAAGGGKRLM
LILNKVDLVPPPVLKGWLTYLRRFFPTLPLRASNPAPNARTFSHRDITVQSTSAALFRAL
KAYAAARNLKRAIAVGVIGYPNVGKSSVINALLSRLPGSARGGRTPCPAGAEAGVTTAIR
AVKIDSKLTLLDSPGIVFPSTASSQTFIPKNPVEAHAHLVLLNAIPPKQIEDPVPAVTLL
LKRLSATPELMDRLMQVYDIPPLLKDPSQGGDATMDFLVQVARKRGRLGRGGVPNIQAAA
MTVVTDWRDGRIQGWTEPPKIAVEGVKEGNEGKVVRKIADQEVAPDQKIIVTEWAKEFKL
AGLWGDEEQTEEGDKMEA

Sequence of entity 8 (CN), FASTA

>8PV2_8 Eukaryotic translation initiation factor 6 (chains CN)
MAVRAQFENSNEVGVFATLTNSYCLVALGASENFYSVFEAELQDVIPICRTTIAGTRIIG
RLTAGNRKGLLVPTTTTDQELQHLRNSLPDDIRIQRIEERLSALGNVIVCNDHTALIHPD
LERETEEIIADVLGVEVFRQTIADHVLVGSYMALSNQGGLVHPKTSIQDQDELSSLLGVP
LVAGSVNRGSNVIGGGMVVNDWLAVTGLDTTAPELSVIESVFRLGEGAGPGAINTSMKNT
IVESFY

Sequence of entity 9 (CO), FASTA

>8PV2_9 DUF2423 domain-containing protein (chains CO)
MAKSARASRIKENHQRFKKNIAGPVEAARLERLSAKLMAIAQAPKPDIEMKEESEATAEQ
PKESTQTKDDTAMDVDGAKPTLSGVKSGKSIGRKDSRKRRGKKSSIVFPMKGPKRNNLKK

Sequence of entity 10 (CQ), FASTA

>8PV2_10 Ribosome biogenesis protein RLP24 (chains CQ)
MRIENCFFCGRPAWPSKGITFMRNDGKAFRFCRSKCHKNFKMKRNPRKLKWTKAYRKNAG
KEMVVDSTLQFAARRNVPVRYNRELWQKTLKAMERISEIRARRERVFYKKRMAGKRAREV
AAARKLVAENEHLLPRLRGSEKRRLAELAAERGVDVEELEREELAKLASKKKSKAFGGEV
RRVRVRTDGGVEEITESFGGKNVDEEMDDDDHDDSDRDDDDMDTD

Sequence of entity 11 (Cb), FASTA

>8PV2_11 Zinc finger domain-containing protein (chains Cb)
MGVFAKRTMTKTRRRLRDLDQIERDLRSPRHLQQYKETKAAEDLPGLGLYYCIECAKWFE
SETSLVGHRKGKPHKRRLKQLKEGAYTHEEAMAAIGYRIDNGKKTTEQPKTQDVEMS

Sequence of entity 12 (Cd), FASTA

>8PV2_12 Nucleolar GTP-binding protein 2 (chains Cd)
MGTGKKEKNRLLREGRTPGDPHVKGENFYRSAKKIKTLNILKEGKPIRDSKGKIVKAASF
QSKEVPKAVIEPNRKWFTNTRVISQDTLQSFREAMAEKQKDPYTVLLKSNKLPMSLIRDG
PKLEDGLKKHQAKMTIEREPFSETFGPKAQRKRPKLSFNTVDELAGYSEQSLDSYHARLE
EKKLLSGAAGAAALESEAPVEEDFSVATAKEAIFNKGTSKRIWNELYKVIDSSDVILHVL
DARDPLGTRCRHVEKYLAAEAPHKHLVFVLNKIDLVPSSQAAAWIRILQKDHPTCAMRAS
ITNPFGRGSLIDLLRQFSVLHKDRKQISVGLIGYPNVGKSSIINALRGKAVAKVAPIPGE
TKVWQYVTLMKRIYLIDCPGIVPPNQHDTPEDLLLRGVVRVENVEHPEQYIPAVLRKVKQ
HHMERTYELRGWKDHIEFLEMLARKSGRLLKGGEPDVDGVAKQVLNDFMRGKIPWFTPAP
EPEKGDEPVIEGRAGRLGEMPKKRKREETESVADTSMADSTAAAEPEDESEDEGSDSESE
FSGFSSDSDSEVEVEVGKEAQDDSAPDMIPLDETSDEDEYNEEDDDGEEDGSEDGDEMSD
NDIEDASDIESESESEPSPPKRRKKAR

Ligands and cofactors

ID	Name	Formula	Copies
GTP	Guanosine-5'-triphosphate	C10 H16 N5 O14 P3	2
MG	Magnesium ion	Mg	3
ZN	Zinc ion	Zn	5

Primary citation

Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Thoms, M., Lau, B., Cheng, J. et al. EMBO Rep (2023) 24:e57984-e57984. DOI 10.15252/embr.202357984 · PubMed

Other PDB entries of the same protein (UniProt G0S616 (AlphaFold model), which also has an AlphaFold model), best resolution first:

4NWB 1.8 Å, Crystal structure of Mrt4
8PV7 2.12 Å, Chaetomium thermophilum pre-60S State 1 - pre-5S rotation (Arx1/Nog2 state) - Composite…
8PVL 2.19 Å, Chaetomium thermophilum pre-60S State 7 - pre-5S rotation lacking Utp30/ITS2 - composite…
9XB4 2.5 Å, Crystal structure of Mrt4 (L96C) mutant
8PVK 2.55 Å, Chaetomium thermophilum pre-60S State 5 - pre-5S rotation - L1 inward - composite…
8PV1 2.56 Å, Chaetomium thermophilum pre-60S State 6 - pre-5S rotation - L1 intermediate - composite…
8I9Z 2.7 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Spb4
8IA0 2.7 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Puf6
8I9X 2.8 Å, Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-1
8PV3 2.8 Å, Chaetomium thermophilum pre-60S State 9 - pre-5S rotation - immature H68/H69 - composite…
8PV5 2.86 Å, Chaetomium thermophilum pre-60S State 8 - pre-5S rotation without Foot - composite…
8PV4 2.9 Å, Chaetomium thermophilum pre-60S State 2 - pre-5S rotation with Rix1 complex - composite…

Browse structure collections

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