8QOI: Human 80S ribosome

Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA. Determined by electron microscopy at 1.9 Å resolution. Released 12 Jun 2024.

Method
Electron microscopy
Resolution
1.9 Å
Organism
Homo sapiens
Chains
79
Atoms
233,370
Mol. weight
3790.36 kDa
Ligands
MG, SPD, ZN
Released
12 Jun 2024

Explore 8QOI in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

8QOI contains 591 α-helices and 559 β-strands across 75 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain La: 7 helices, 7 β-strands

ElementResiduesLengthSheet
α-helix3-53
α-helix8-114
α-helix42-487
α-helix65-684
β-strand72-74312
α-helix75-817
α-helix84-918
β-strand98194
β-strand100-102313
β-strand110-112312
β-strand123-126413
β-strand128-129212
α-helix131-1399
β-strand143-146413
Chain LA: 13 helices, 18 β-strands
ElementResiduesLengthSheet
α-helix6-94
α-helix10-123
α-helix14-163
β-strand28115
α-helix29-324
α-helix34-385
β-strand41-49915
β-strand58-64715
β-strand71-77715
α-helix781
β-strand79116
β-strand83117
β-strand87-90415
β-strand101-103315
α-helix104-1063
α-helix1081
β-strand112-114315
β-strand116118
β-strand126118
β-strand134-140715
β-strand145-149515
β-strand155-159515
β-strand163-166415
β-strand169116
α-helix174-1763
α-helix182-1909
α-helix201-2033
α-helix206-2083
β-strand224-225219
α-helix229-2302
β-strand237-238219
Chain Lb: 7 helices, 0 β-strands
ElementResiduesLengthSheet
α-helix12-187
α-helix21-244
α-helix37-4812
α-helix49-513
α-helix54-6613
α-helix92-998
α-helix106-11611
Chain LB: 22 helices, 20 β-strands
ElementResiduesLengthSheet
α-helix9-102
α-helix14-163
α-helix20-223
α-helix32-354
α-helix40-412
β-strand42-43223
β-strand45-591524
β-strand71-801024
α-helix82-832
β-strand84-951223
β-strand98-106923
α-helix112-1154
α-helix116-1183
α-helix131-1344
α-helix135-1373
α-helix140-15617
β-strand159-165723
α-helix168-1703
α-helix178-1792
β-strand180-186723
α-helix193-1997
β-strand201123
β-strand203-205323
α-helix207-2093
β-strand216-222724
α-helix223-2242
β-strand225-229525
α-helix231-2344
α-helix237-2415
β-strand270-273425
β-strand276-2881324
β-strand292-293226
β-strand297-298226
α-helix3161
β-strand320127
β-strand324127
β-strand330-334524
β-strand344-349624
α-helix357-3604
β-strand365-368424
α-helix382-3887
α-helix393-4019
Chain Lc: 4 helices, 4 β-strands
ElementResiduesLengthSheet
α-helix10-2112
β-strand26-29428
α-helix31-399
β-strand45-48428
α-helix54-6714
β-strand70-73428
α-helix78-847
β-strand93-98628
Chain LC: 26 helices, 11 β-strands
ElementResiduesLengthSheet
α-helix5-62
β-strand7-11530
β-strand17-23730
α-helix24-252
α-helix26-294
α-helix34-4411
α-helix45-484
α-helix49-513
β-strand65-66231
β-strand77-78231
β-strand90131
α-helix100-1012
α-helix117-13115
α-helix134-1385
β-strand152-154330
α-helix156-1605
α-helix164-17310
α-helix177-18610
β-strand188-189232
α-helix190-1912
α-helix193-1975
β-strand201-202232
α-helix2071
β-strand208-211430
α-helix217-2215
β-strand228-231430
α-helix237-2404
α-helix242-2443
β-strand250-253430
α-helix254-2585
α-helix260-2645
α-helix279-2824
α-helix289-2935
α-helix296-3016
α-helix302-3054
α-helix322-3287
α-helix331-36737
Chain Ld: 4 helices, 5 β-strands
ElementResiduesLengthSheet
β-strand21-28833
α-helix29-324
α-helix38-403
α-helix41-5717
β-strand62-64333
α-helix66-727
β-strand83-921033
β-strand102-108733
β-strand120-122333
Chain LD: 21 helices, 10 β-strands
ElementResiduesLengthSheet
α-helix10-145
α-helix18-203
α-helix21-244
α-helix30-378
α-helix38-403
α-helix41-433
β-strand49-55738
β-strand60-68938
β-strand71-79938
α-helix80-823
β-strand85139
β-strand87139
α-helix94-11320
α-helix132-1343
α-helix139-1424
β-strand143140
β-strand145-147338
α-helix158-16912
β-strand172140
β-strand183-184241
β-strand189-190241
α-helix192-1954
α-helix202-21312
α-helix216-2227
α-helix224-2274
α-helix228-2303
α-helix233-2353
α-helix236-24914
α-helix255-2573
α-helix268-2725
α-helix273-29321

67 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

MoleculeChainsTypeLengthOrganismUniProt
28S rRNA (3773-mer)L5RNA5069Homo sapiens
5S rRNA (120-mer)L7RNA120Homo sapiens
5.8S rRNA (156-mer)L8RNA157Homo sapiens
60S ribosomal protein L8LAprotein257Homo sapiensP62917 (AlphaFold model)
Large ribosomal subunit protein uL3LBprotein402Homo sapiensP39023 (AlphaFold model)
Large ribosomal subunit protein uL4LCprotein368Homo sapiensP36578 (AlphaFold model)
Large ribosomal subunit protein uL18LDprotein293Homo sapiensP46777 (AlphaFold model)
Large ribosomal subunit protein eL6LEprotein247Homo sapiensQ02878
Large ribosomal subunit protein uL30LFprotein248Homo sapiensP18124
60S ribosomal protein L7aLGprotein266Homo sapiensP62424
60S ribosomal protein L9LHprotein192Homo sapiensP32969
60S ribosomal protein L10-likeLIprotein214Homo sapiensQ96L21

67 more molecules are not listed.

Sequence of entity 1 (L5), FASTA
>8QOI_1 28S rRNA (3773-MER) (chains L5)
CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAG
AAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGA
AUCCCCGCCCCGCGGCGGGGCGCGGGACAUGUGGCGUACGGAAGACCCGCUCCCCGGCGC
CGCUCGUGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCG
GUAGCGGCCCCCGGCGCGCCGGGCCCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCA
GCCCAAAGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAA
CAAGUACCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAA
CCGUUAAGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGC
GGGUCCGGCCGUGUCGGCGGCCCGGCGGAUCUUUCCCGCCCCCCGUUCCUCCCGACCCCU
CCACCCGCCCUCCCUUCCCCCGCCGCCCCUCCUCCUCCUCCCCGGAGGGGGCGGGCUCCG
GCGGGUGCGGGGGUGGGCGGGCGGGGCCGGGGGUGGGGUCGGCGGGGGACCGUCCCCCGA
CCGGCGACCGGCCGCCGCCGGGCGCAUUUCCACCGCGGCGGUGCGCCGCGACCGGCUCCG
GGACGGCUGGGAAGGCCCGGCGGGGAAGGUGGCUCGGGGGGCCCCGUCCGUCCGUCCGUC
CGUCCUCCUCCUCCCCCGUCUCCGCCCCCCGGCCCCGCGUCCUCCCUCGGGAGGGCGCGC
GGGUCGGGGCGGCGGCGGCGGCGGCGGUGGCGGCGGCGGCGGCGGCGGCGGGACCGAAAC
CCCCCCGAGUGUUACAGCCCCCCCGGCAGCAGCACUCGCCGAAUCCCGGGGCCGAGGGAG
CGAGACCCGUCGCCGCGCUCUCCCCCCUCCCGGCGCCCACCCCCGCGGGGAAUCCCCCGC
GAGGGGGGUCUCCCCCGCGGGGGCGCGCCGGCGUCUCCUCGUGGGGGGGCCGGGCCACCC
CUCCCACGGCGCGACCGCUCUCCCACCCCUCCUCCCCGCGCCCCCGCCCCGGCGACGGGG
GGGGUGCCGCGCGCGGGUCGGGGGGCGGGGCGGACUGUCCCCAGUGCGCCCCGGGCGGGU
CGCGCCGUCGGGCCCGGGGGAGGUUCUCUCGGGGCCACGCGCGCGUCCCCCGAAGAGGGG
GACGGCGGAGCGAGCGCACGGGGUCGGCGGCGACGUCGGCUACCCACCCGACCCGUCUUG
AAACACGGACCAAGGAGUCUAACACGUGCGCGAGUCGGGGGCUCGCACGAAAGCCGCCGU
GGCGCAAUGAAGGUGAAGGCCGGCGCGCUCGCCGGCCGAGGUGGGAUCCCGAGGCCUCUC
CAGUCCGCCGAGGGUGCACCACCGGCCCGUCUCGCCCGCCGCGCCGGGGAGGUGGAGCAC
GAGCGCACGUGUUAGGACCCGAAAGAUGGUGAACUAUGCCUGGGCAGGGCGAAGCCAGAG
GAAACUCUGGUGGAGGUCCGUAGCGGUCCUGACGUGCAAAUCGGUCGUCCGACCUGGGUA
UAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCCUCCGAAGUUUCCCUCAGG
AUAGCUGGCGCUCUCGCAGACCCGACGCACCCCCGCCACGCAGUUUUAUCCGGUAAAGCG
AAUGAUUAGAGGUCUUGGGGCCGAAACGAUCUCAACCUAUUCUCAAACUUUAAAUGGGUA
AGAAGCCCGGCUCGCUGGCGUGGAGCCGGGCGUGGAAUGCGAGUGCCUAGUGGGCCACUU
UUGGUAAGCAGAACUGGCGCUGCGGGAUGAACCGAACGCCGGGUUAAGGCGCCCGAUGCC
GACGCUCAUCAGACCCCAGAAAAGGUGUUGGUUGAUAUAGACAGCAGGACGGUGGCCAUG
GAAGUCGGAAUCCGCUAAGGAGUGUGUAACAACUCACCUGCCGAAUCAACUAGCCCUGAA
AAUGGAUGGCGCUGGAGCGUCGGGCCCAUACCCGGCCGUCGCCGGCAGUCGAGAGUGGAC
GGGAGCGGCGGGGGCGGCGCGCGCGCGCGCGCGUGUGGUGUGCGUCGGAGGGCGGCGGCG
GCGGCGGCGGCGGGGGUGUGGGGUCCUUCCCCCGCCCCCCCCCCCACGCCUCCUCCCCUC
CUCCCGCCCACGCCCCGCUCCCCGCCCCCGGAGCCCCGCGGACGCUACGCCGCGACGAGU
AGGAGGGCCGCUGCGGUGAGCCUUGAAGCCUAGGGCGCGGGCCCGGGUGGAGCCGCCGCA
GGUGCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAACGAGAACUUUGAAGGCCGAAGUGGA
GAAGGGUUCCAUGUGAACAGCAGUUGAACAUGGGUCAGUCGGUCCUGAGAGAUGGGCGAG
CGCCGUUCCGAAGGGACGGGCGAUGGCCUCCGUUGCCCUCGGCCGAUCGAAAGGGAGUCG
GGUUCAGAUCCCCGAAUCCGGAGUGGCGGAGAUGGGCGCCGCGAGGCGUCCAGUGCGGUA
ACGCGACCGAUCCCGGAGAAGCCGGCGGGAGCCCCGGGGAGAGUUCUCUUUUCUUUGUGA
AGGGCAGGGCGCCCUGGAAUGGGUUCGCCCCGAGAGAGGGGCCCGUGCCUUGGAAAGCGU
CGCGGUUCCGGCGGCGUCCGGUGAGCUCUCGCUGGCCCUUGAAAAUCCGGGGGAGAGGGU
GUAAAUCUCGCGCCGGGCCGUACCCAUAUCCGCAGCAGGUCUCCAAGGUGAACAGCCUCU
GGCAUGUUGGAACAAUGUAGGUAAGGGAAGUCGGCAAGCCGGAUCCGUAACUUCGGGAUA
AGGAUUGGCUCUAAGGGCUGGGUCGGUCGGGCUGGGGCGCGAAGCGGGGCUGGGCGCGCG
CCGCGGCUGGACGAGGCGCCGCCGCCCCCCCCACGCCCGGGGCACCCCCCUCGCGGCCCU
CCCCCGCCCCACCCCGCGCGCGCCGCUCGCUCCCUCCCCGCCCCGCGCCCUCUCUCUCUC
UCUCUCCCCCGCUCCCCGUCCUCCCCCCUCCCCGGGGGAGCGCCGCGUGGGGGCGGCGGC
GGGGGGAGAAGGGUCGGGGCGGCAGGGGCCGGCGGCGGCCCGCCGCGGGGCCCCGGCGGC
GGGGGCACGGUCCCCCGCGAGGGGGGCCCGGGCACCCGGGGGGCCGGCGGCGGCGGCGAC
UCUGGACGCGAGCCGGGCCCUUCCCGUGGAUCGCCCCAGCUGCGGCGGGCGUCGCGGCCG
CCCCCGGGGAGCCCGGCGGGCGCCGGCGCGCCCCCCCCCCCACCCCACGUCUCGUCGCGC
GCGCGUCCGCUGGGGGCGGGGAGCGGUCGGGCGGCGGCGGUCGGCGGGCGGCGGGGCGGG
GCGGUUCGUCCCCCCGCCCUACCCCCCCGGCCCCGUCCGCCCCCCGUUCCCCCCUCCUCC
UCGGCGCGCGGCGGCGGCGGCGGCAGGCGGCGGAGGGGCCGCGGGCCGGUCCCCCCCGCC
GGGUCCGCCCCCGGGGCCGCGGUUCCGCGCGGCGCCUCGCCUCGGCCGGCGCCUAGCAGC
CGACUUAGAACUGGUGCGGACCAGGGGAAUCCGACUGUUUAAUUAAAACAAAGCAUCGCG
AAGGCCCGCGGCGGGUGUUGACGCGAUGUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGU
GAAGAAAUUCAAUGAAGCGCGGGUAAACGGCGGGAGUAACUAUGACUCUCUUAAGGUAGC
CAAAUGCCUCGUCAUCUAAUUAGUGACGCGCAUGAAXGGAUGAACGAGAUUCCCACUGUC
CCUACCUACUAUCCAGCGAAACCACAGCCAAGGGAACGGGCUUGGCGGAAUCAGCGGGGA
AAGAAGACCCUGUUGAGCUUGACUCUAGUCUGGCACGGUGAAGAGACAUGAGAGGUGUAG
AAUAAGUGGGAGGCCCCCGGCGCCCCCCCGGUGUCCCCGCGAGGGGCCCGGGGCGGGGUC
CGCCGGCCCUGCGGGCCGCCGGUGAAAUACCACUACUCUGAUCGUUUUUUCACUGACCCG
GUGAGGCGGGGGGGCGAGCCCCGAGGGGCUCUCGCUUCUGGCGCCAAGCGCCCGGCCGCG
CGCCGGCCGGGCGCGACCCGCUCCGGGGACAGUGCCAGGUGGGGAGUUUGACUGGGGCGG
UACACCUGUCAAACGGUAACGCAGGUGUCCUAAGGCGAGCUCAGGGAGGACAGAAACCUC
CCGUGGAGCAGAAGGGCAAAAGCUCGCUUGAUCUUGAUUUUCAGUACGAAUACAGACCGU
GAAAGCGGGGCCUUACGAUCCUUCUGACCUUUUGGGUUUUAAGCAGGAGGUGUCAGAAAA
GUUACCACAGGGAUAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUUUGA
UCCUUCGAUGUCGGCUCUUCCUAUCAUUGUGAAGCAGAAUUCACCAAGCGUUGGAUUGUU
CACCCACUAAUAGGGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACC
CUACUGAUGAUGUGUUGUUGCCAUGGUAAUCCUGCUCAGUACGAGAGGAACCGCAGGUUC
AGACAUUUGGUGUAUGUGCUUGGCUGAGGAGCCAAUGGGGCGAAGCUACCAUCUGUGGGA
UUAUGACUGAACGCCUCUAAGUCAGAAUCCCGCCCAGGCGGAACGAUACGGCAGCGCCGC
GGAGCCUCGGUUGGCCUCGGAUAGCCGGUCCCCCGCCUGUCCCCGCCGGCGGGCCGCCCC
CCCCCUCCACGCGCCCCGCGCGCGCGGGAGGGCGCGUGCCCCGCCGCGCGCCGGGACCGG
GGUCCGGUGCGGAGUGCCCUUCGUCCUGGGAAACGGGGCGCGGCCGGAAAGGCGGCCGCC
CCCUCGCCCGUCACGCACCGCACGUUCGUGGGGAACCUGGCGCUAAACCAUUCGUAGACG
ACCUGCUUCUGGGUCGGGGU
Sequence of entity 2 (L7), FASTA
>8QOI_2 5S rRNA (120-MER) (chains L7)
GUCUACGGCCAUACCACCCUGAACGCGCCCGAUCUCGUCUGAUCUCGGAAGCUAAGCAGG
GUCGGGCCUGGUUAGUACUUGGAUGGGAGACCGCCUGGGAAUACCGGGUGCUGUAGGCUU
Sequence of entity 3 (L8), FASTA
>8QOI_3 5.8S rRNA (156-MER) (chains L8)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCUU
Sequence of entity 4 (LA), FASTA
>8QOI_4 60S ribosomal protein L8 (chains LA)
MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAK
VVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKP
GDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPIL
KAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAA
RRTGRLRGTKTVQEKEN
Sequence of entity 5 (LB), FASTA
>8QOI_5 Large ribosomal subunit protein uL3 (chains LB)
SHRKFSAPRHGSLGFLPRKRSSRHRGKVKSFPKDDPSKPVHLTAFLGYKAGMTHIVREVD
RPGSKVNKKEVVEAVTIVETPPMVVVGIVGYVETPRGLRTFKTVFAEHISDECKRRFYKN
WHKSKKKAFTKYCKKWQDEDGKKQLEKDFSSMKKYCQVIRVIAHTQMRLLPLRQKKAHLM
EIQVNGGTVAEKLDWARERLEQQVPVNQVFGQDEMIDVIGVTKGKGYKGVTSRWHTKKLP
RKTHRGLRKVACIGAWHPARVAFSVARAGQKGYHHRTEINKKIYKIGQGYLIKDGKLIKN
NASTDYDLSDKSINPLGGFVHYGEVTNDFVMLKGCVVGTKKRVLTLRKSLLVQTKRRALE
KIDLKFIDTTSKFGHGRFQTMEEKKAFMGPLKKDRIAKEEGA
Sequence of entity 6 (LC), FASTA
>8QOI_6 Large ribosomal subunit protein uL4 (chains LC)
MACARPLISVYSEKGESSGKNVTLPAVFKAPIRPDIVNFVHTNLRKNNRQPYAVSELAGH
QTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQK
RYAICSALAASALPALVMSKGHRIEEVPELPLVVEDKVEGYKKTKEAVLLLKKLKAWNDI
KKVYASQRMRAGKGKMRNRRRIQRRGPCIIYNEDNGIIKAFRNIPGITLLNVSKLNILKL
APGGHVGRFCIWTESAFRKLDELYGTWRKAASLKSNYNLPMHKMINTDLSRILKSPEIQR
ALRAPRKKIHRRVLKKNPLKNLRIMLKLNPYAKTMRRNTILRQARNHKLRVDKAAAAAAA
LQAKSDEK
Sequence of entity 7 (LD), FASTA
>8QOI_7 Large ribosomal subunit protein uL18 (chains LD)
GFVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDII
CQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEG
QVEVTGDEYNVESIDGQPGAFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFP
GYDSESKEFNAEVHRKHIMGQNVADYMRYLMEEDEDAYKKQFSQYIKNSVTPDMMEEMYK
KAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERA
Sequence of entity 8 (LE), FASTA
>8QOI_8 Large ribosomal subunit protein eL6 (chains LE)
PHCSRNPVLVRGIGRYSRSAMYSRKAMYKRKYSAAKSKVEKKKKEKVLATVTKPVGGDKN
GGTRVVKLRKMPRYYPTEDVPRKLLSHGKKPFSQHVRKLRASITPGTILIILTGRHRGKR
VVFLKQLASGLLLVTGPLVLNRVPLRRTHQKFVIATSTKIDISNVKIPKHLTDAYFKKKK
LRKPRHQEGEIFDTEKEKYEITEQRKIDQKAVDSQILPKIKAIPQLQGYLRSVFALTNGI
YPHKLVF
Sequence of entity 9 (LF), FASTA
>8QOI_9 Large ribosomal subunit protein uL30 (chains LF)
MEGVEEKKKEVPAVPETLKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKE
YRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNG
TFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLG
KYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQI
NRLIRRMN
Sequence of entity 10 (LG), FASTA
>8QOI_10 60S ribosomal protein L7a (chains LG)
MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRY
IRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEK
KAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVP
YCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGN
VLGPKSVARIAKLEKAKAKELATKLG
Sequence of entity 11 (LH), FASTA
>8QOI_11 60S ribosomal protein L9 (chains LH)
MKTILSNQTVDIPENVDITLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKW
WGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGE
KYIRRVRMRPGVACSVSQAQKDELILEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIY
VSEKGTVQQADE
Sequence of entity 12 (LI), FASTA
>8QOI_12 60S ribosomal protein L10-like (chains LI)
MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQL
SSEALEAARICANKYMVKSCGRDGFHMRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFG
KPQGTVARVHIGQVIMSIRTKLQNEEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADE
FEDMVAKKCLIPDGCGVKYVPSHGPLDKWRVLHS

Ligands and cofactors

IDNameFormulaCopies
MGMagnesium ionMg292
SPDSpermidineC7 H19 N32
ZNZinc ionZn8

Water and common crystallization additives (K) are not listed.

Primary citation

The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA. Holvec, S., Barchet, C., Lechner, A. et al. Nat Struct Mol Biol (2024) 31:1251-1264. DOI 10.1038/s41594-024-01274-x · PubMed

Other PDB entries of the same protein (UniProt P62917 (AlphaFold model), which also has an AlphaFold model), best resolution first:

Browse structure collections

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