9PB7: TFIIH of PIC-Med-SWI/SNF
TFIIH of PIC-Med-SWI/SNF. Determined by electron microscopy at 4.4 Å resolution. Released 30 Sept 2026.
- Method
- Electron microscopy
- Resolution
- 4.4 Å
- Organism
- Saccharomyces cerevisiae
- Chains
- 12
- Atoms
- 26,523
- Mol. weight
- 600.16 kDa
- Ligands
- ZN, SF4
- Released
- 30 Sept 2026
Explore 9PB7 in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
9PB7 contains 181 α-helices and 132 β-strands across 10 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain 0: 43 helices, 25 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 4 | 1 | 3 |
| β-strand | 9 | 1 | 3 |
| β-strand | 17 | 1 | 4 |
| α-helix | 19-31 | 13 | |
| β-strand | 36-41 | 6 | 5 |
| α-helix | 49-62 | 14 | |
| β-strand | 69-73 | 5 | 5 |
| α-helix | 76-95 | 20 | |
| α-helix | 100-101 | 2 | |
| β-strand | 104-107 | 4 | 5 |
| α-helix | 112-114 | 3 | |
| α-helix | 118-121 | 4 | |
| α-helix | 126-135 | 10 | |
| α-helix | 140-147 | 8 | |
| α-helix | 157-160 | 4 | |
| α-helix | 167-169 | 3 | |
| β-strand | 174-175 | 2 | 5 |
| α-helix | 178-186 | 9 | |
| α-helix | 192-196 | 5 | |
| β-strand | 205-209 | 5 | 5 |
| α-helix | 211-214 | 4 | |
| α-helix | 219-225 | 7 | |
| β-strand | 231-234 | 4 | 5 |
| α-helix | 240-242 | 3 | |
| α-helix | 245-248 | 4 | |
| β-strand | 250-252 | 3 | 6 |
| α-helix | 256-277 | 22 | |
| α-helix | 280-291 | 12 | |
| α-helix | 295-298 | 4 | |
| α-helix | 328-344 | 17 | |
| α-helix | 345-347 | 3 | |
| β-strand | 352-354 | 3 | 6 |
| α-helix | 356-366 | 11 | |
| α-helix | 371-374 | 4 | |
| α-helix | 377-386 | 10 | |
| α-helix | 398-411 | 14 | |
| β-strand | 416-421 | 6 | 6 |
| β-strand | 434-439 | 6 | 6 |
| α-helix | 443-452 | 10 | |
| β-strand | 455-458 | 4 | 5 |
| α-helix | 468-472 | 5 | |
| β-strand | 479-482 | 4 | 5 |
| β-strand | 493-497 | 5 | 7 |
| β-strand | 499 | 1 | 8 |
| β-strand | 505 | 1 | 8 |
| α-helix | 510-512 | 3 | |
| α-helix | 516-532 | 17 | |
| β-strand | 537-541 | 5 | 7 |
| α-helix | 544-556 | 13 | |
| α-helix | 560-564 | 5 | |
| β-strand | 568-571 | 4 | 7 |
| α-helix | 576-591 | 16 | |
| β-strand | 596-601 | 6 | 7 |
| α-helix | 614-616 | 3 | |
| β-strand | 619-623 | 5 | 7 |
| α-helix | 633-646 | 14 | |
| α-helix | 650-655 | 6 | |
| α-helix | 662-665 | 4 | |
| β-strand | 678-682 | 5 | 7 |
| α-helix | 684-688 | 5 | |
| α-helix | 690-692 | 3 | |
| α-helix | 695-698 | 4 | |
| α-helix | 704-707 | 4 | |
| β-strand | 708 | 1 | 7 |
| α-helix | 710-724 | 15 | |
| α-helix | 730-732 | 3 | |
| β-strand | 739 | 1 | 4 |
| α-helix | 741-751 | 11 | |
Chain 1: 30 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 171-176 | 6 | |
| α-helix | 178-185 | 8 | |
| α-helix | 189-196 | 8 | |
| α-helix | 197-202 | 6 | |
| α-helix | 206-210 | 5 | |
| α-helix | 214-224 | 11 | |
| α-helix | 253-262 | 10 | |
| α-helix | 264-273 | 10 | |
| α-helix | 280-287 | 8 | |
| α-helix | 292-297 | 6 | |
| α-helix | 299-301 | 3 | |
| α-helix | 309-312 | 4 | |
| α-helix | 315-328 | 14 | |
| α-helix | 332-334 | 3 | |
| α-helix | 335-337 | 3 | |
| α-helix | 342-344 | 3 | |
| α-helix | 356-358 | 3 | |
| β-strand | 362 | 1 | 38 |
| β-strand | 368 | 1 | 38 |
| α-helix | 371-389 | 19 | |
| α-helix | 414-419 | 6 | |
| β-strand | 432 | 1 | 33 |
| β-strand | 434 | 1 | 29 |
| α-helix | 442-444 | 3 | |
| α-helix | 470-480 | 11 | |
| α-helix | 487-489 | 3 | |
| α-helix | 490-492 | 3 | |
| α-helix | 493-513 | 21 | |
| α-helix | 544-568 | 25 | |
| α-helix | 573-575 | 3 | |
| α-helix | 576-602 | 27 | |
| α-helix | 609-613 | 5 | |
| α-helix | 614-616 | 3 | |
| α-helix | 617-638 | 22 | |
Chain 2: 26 helices, 21 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 6-14 | 9 | |
| α-helix | 19-26 | 8 | |
| α-helix | 29-36 | 8 | |
| α-helix | 41-49 | 9 | |
| β-strand | 57-58 | 2 | 39 |
| α-helix | 60-63 | 4 | |
| β-strand | 66 | 1 | 25 |
| α-helix | 68-70 | 3 | |
| α-helix | 72-84 | 13 | |
| β-strand | 87 | 1 | 40 |
| β-strand | 90 | 1 | 39 |
| α-helix | 92-94 | 3 | |
| β-strand | 97-98 | 2 | 39 |
| β-strand | 100 | 1 | 40 |
| α-helix | 102-112 | 11 | |
| β-strand | 124 | 1 | 41 |
| α-helix | 131-136 | 6 | |
| α-helix | 137-151 | 15 | |
| α-helix | 161-168 | 8 | |
| β-strand | 174 | 1 | 42 |
| β-strand | 183 | 1 | 42 |
| α-helix | 186-193 | 8 | |
| α-helix | 196-208 | 13 | |
| α-helix | 218-228 | 11 | |
| α-helix | 231-232 | 2 | |
| β-strand | 237-238 | 2 | 41 |
| α-helix | 244-254 | 11 | |
| β-strand | 260 | 1 | 43 |
| β-strand | 268-269 | 2 | 41 |
| β-strand | 270 | 1 | 43 |
| α-helix | 274-277 | 4 | |
| β-strand | 338-340 | 3 | 13 |
| β-strand | 346-350 | 5 | 13 |
| α-helix | 354-356 | 3 | |
| α-helix | 358-361 | 4 | |
| β-strand | 365-370 | 6 | 13 |
| β-strand | 373-377 | 5 | 13 |
| α-helix | 384-388 | 5 | |
| α-helix | 393-402 | 10 | |
| α-helix | 406-422 | 17 | |
| α-helix | 435-447 | 13 | |
| β-strand | 452-457 | 6 | 1 |
| β-strand | 458-459 | 2 | 44 |
| α-helix | 465-477 | 13 | |
| β-strand | 481-485 | 5 | 44 |
| β-strand | 490-493 | 4 | 44 |
| α-helix | 498-506 | 9 | |
Chain 3: 7 helices, 8 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 12-13 | 2 | 9 |
| β-strand | 18-19 | 2 | 9 |
| α-helix | 20-22 | 3 | |
| β-strand | 28-29 | 2 | 10 |
| β-strand | 30 | 1 | 11 |
| β-strand | 38-39 | 2 | 10 |
| α-helix | 40-45 | 6 | |
| β-strand | 52-53 | 2 | 12 |
| β-strand | 62-63 | 2 | 12 |
| α-helix | 65-67 | 3 | |
| β-strand | 69 | 1 | 11 |
| α-helix | 76-89 | 14 | |
| α-helix | 96-99 | 4 | |
| α-helix | 103-122 | 20 | |
| α-helix | 126-134 | 9 | |
Chain 4: 15 helices, 13 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 24-31 | 8 | 24 |
| α-helix | 34-41 | 8 | |
| α-helix | 51-65 | 15 | |
| β-strand | 72-78 | 7 | 24 |
| β-strand | 83-87 | 5 | 24 |
| α-helix | 89-90 | 2 | |
| α-helix | 116-129 | 14 | |
| α-helix | 131-137 | 7 | |
| α-helix | 149-166 | 18 | |
| β-strand | 173-178 | 6 | 24 |
| α-helix | 185-186 | 2 | |
| α-helix | 190-192 | 3 | |
| α-helix | 193-206 | 14 | |
| β-strand | 210-215 | 6 | 24 |
| α-helix | 222-229 | 8 | |
| β-strand | 235-238 | 4 | 24 |
| α-helix | 244-250 | 7 | |
| β-strand | 262 | 1 | 25 |
| α-helix | 263-264 | 2 | |
| β-strand | 275 | 1 | 26 |
| β-strand | 282 | 1 | 26 |
| β-strand | 285-289 | 5 | 27 |
| β-strand | 295 | 1 | 27 |
| α-helix | 299-300 | 2 | |
| β-strand | 304-305 | 2 | 28 |
| β-strand | 310-311 | 2 | 28 |
| α-helix | 314-320 | 7 | |
| α-helix | 322-324 | 3 | |
Chain 5: 3 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 6-11 | 6 | 1 |
| α-helix | 14-26 | 13 | |
| β-strand | 31-33 | 3 | 2 |
| β-strand | 41-42 | 2 | 2 |
| α-helix | 44-46 | 3 | |
| α-helix | 47-58 | 12 | |
Chain 6: 21 helices, 23 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 75-78 | 4 | |
| α-helix | 83-86 | 4 | |
| α-helix | 97-109 | 13 | |
| α-helix | 110-112 | 3 | |
| β-strand | 118 | 1 | 29 |
| β-strand | 120 | 1 | 30 |
| β-strand | 124 | 1 | 31 |
| β-strand | 128-131 | 4 | 32 |
| α-helix | 134-136 | 3 | |
| α-helix | 145-163 | 19 | |
| β-strand | 169-175 | 7 | 32 |
| β-strand | 178-186 | 9 | 32 |
| α-helix | 191-198 | 8 | |
| α-helix | 199-201 | 3 | |
| α-helix | 202-204 | 3 | |
| α-helix | 210-220 | 11 | |
| β-strand | 229 | 1 | 31 |
| β-strand | 231-236 | 6 | 32 |
| α-helix | 247-256 | 10 | |
| β-strand | 260-265 | 6 | 32 |
| α-helix | 271-280 | 10 | |
| β-strand | 289-290 | 2 | 32 |
| α-helix | 294-303 | 10 | |
| α-helix | 307-308 | 2 | |
| β-strand | 309 | 1 | 30 |
| β-strand | 311 | 1 | 33 |
| β-strand | 319-323 | 5 | 27 |
| β-strand | 326-335 | 10 | 34 |
| β-strand | 342-348 | 7 | 34 |
| β-strand | 356 | 1 | 34 |
| β-strand | 361-362 | 2 | 35 |
| β-strand | 369-370 | 2 | 35 |
| α-helix | 373-377 | 5 | |
| α-helix | 380-383 | 4 | |
| α-helix | 385-387 | 3 | |
| α-helix | 389 | 1 | |
| β-strand | 390-393 | 4 | 36 |
| β-strand | 402 | 1 | 37 |
| β-strand | 409 | 1 | 37 |
| α-helix | 410-411 | 2 | |
| β-strand | 423-428 | 6 | 36 |
| β-strand | 435-436 | 2 | 36 |
| α-helix | 438-446 | 9 | |
| α-helix | 452-456 | 5 | |
Chain 7: 31 helices, 29 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 117-118 | 2 | 13 |
| α-helix | 122-124 | 3 | |
| α-helix | 127-129 | 3 | |
| β-strand | 132-134 | 3 | 14 |
| β-strand | 140-143 | 4 | 14 |
| α-helix | 150-155 | 6 | |
| α-helix | 157-159 | 3 | |
| β-strand | 161-165 | 5 | 14 |
| β-strand | 171-175 | 5 | 14 |
| α-helix | 177-182 | 6 | |
| α-helix | 191-197 | 7 | |
| β-strand | 201 | 1 | 14 |
| α-helix | 207-213 | 7 | |
| β-strand | 232-233 | 2 | 15 |
| α-helix | 245-247 | 3 | |
| β-strand | 317-318 | 2 | 15 |
| α-helix | 323-331 | 9 | |
| β-strand | 351 | 1 | 16 |
| β-strand | 356 | 1 | 17 |
| α-helix | 364-373 | 10 | |
| β-strand | 382-385 | 4 | 18 |
| α-helix | 394-403 | 10 | |
| β-strand | 405 | 1 | 16 |
| β-strand | 407-411 | 5 | 19 |
| α-helix | 414-427 | 14 | |
| β-strand | 428 | 1 | 17 |
| α-helix | 432-434 | 3 | |
| β-strand | 435-437 | 3 | 19 |
| β-strand | 438 | 1 | 20 |
| β-strand | 443 | 1 | 20 |
| β-strand | 452-456 | 5 | 19 |
| α-helix | 458-460 | 3 | |
| α-helix | 468-470 | 3 | |
| α-helix | 471-478 | 8 | |
| β-strand | 485-486 | 2 | 18 |
| β-strand | 487 | 1 | 19 |
| α-helix | 490-492 | 3 | |
| α-helix | 496-499 | 4 | |
| β-strand | 510-514 | 5 | 18 |
| α-helix | 522-524 | 3 | |
| α-helix | 526-529 | 4 | |
| β-strand | 536-537 | 2 | 18 |
| α-helix | 540-545 | 6 | |
| β-strand | 552-559 | 8 | 21 |
| α-helix | 563-569 | 7 | |
| α-helix | 574-581 | 8 | |
| α-helix | 586-599 | 14 | |
| β-strand | 605-608 | 4 | 21 |
| α-helix | 612-622 | 11 | |
| β-strand | 626-627 | 2 | 21 |
| α-helix | 633-644 | 12 | |
| β-strand | 651-654 | 4 | 21 |
| α-helix | 656-659 | 4 | |
| β-strand | 669-672 | 4 | 21 |
| α-helix | 680-687 | 8 | |
| β-strand | 703-710 | 8 | 21 |
| α-helix | 715-729 | 15 | |
| β-strand | 735-736 | 2 | 21 |
| α-helix | 742-744 | 3 | |
| α-helix | 755-766 | 12 | |
2 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| General transcription and DNA repair factor IIH subunit TFB5 | 5 | protein | 72 | Saccharomyces cerevisiae | Q3E7C1 (AlphaFold model) |
| General transcription and DNA repair factor IIH helicase subunit XPD/RAD3 | 0 | protein | 778 | Saccharomyces cerevisiae | P06839 (AlphaFold model) |
| RNA polymerase II transcription factor B subunit 3 | 3 | protein | 321 | Saccharomyces cerevisiae | Q03290 (AlphaFold model) |
| General transcription and DNA repair factor IIH helicase subunit XPB | 7 | protein | 843 | Saccharomyces cerevisiae | Q00578 (AlphaFold model) |
| SWI/SNF chromatin-remodeling complex subunit SNF5 | 8 | protein | 905 | Saccharomyces cerevisiae | P18480 |
| Transcription initiation factor TFIID subunit 14 | 9 | protein | 244 | Saccharomyces cerevisiae | P35189 |
| promoter DNA | N | DNA | 26 | Saccharomyces cerevisiae | |
| promoter DNA | T | DNA | 26 | Saccharomyces cerevisiae | |
| General transcription and DNA repair factor IIH subunit TFB4 | 4 | protein | 338 | Saccharomyces cerevisiae | Q12004 |
| General transcription and DNA repair factor IIH subunit SSL1 | 6 | protein | 461 | Saccharomyces cerevisiae | Q04673 |
| General transcription and DNA repair factor IIH subunit TFB1 | 1 | protein | 642 | Saccharomyces cerevisiae | P32776 |
| General transcription and DNA repair factor IIH subunit TFB2 | 2 | protein | 513 | Saccharomyces cerevisiae | Q02939 |
Sequence of entity 1 (5), FASTA
>9PB7_1 General transcription and DNA repair factor IIH subunit TFB5 (chains 5)
MARARKGALVQCDPSIKALILQIDAKMSDIVLEELDDTHLLVNPSKVEFVKHELNRLLSK
NIYNPMDEEENQ
Sequence of entity 2 (0), FASTA
>9PB7_2 General transcription and DNA repair factor IIH helicase subunit XPD/RAD3 (chains 0)
MKFYIDDLPVLFPYPKIYPEQYNYMCDIKKTLDVGGNSILEMPSGTGKTVSLLSLTIAYQ
MHYPEHRKIIYCSRTMSEIEKALVELENLMDYRTKELGYQEDFRGLGLTSRKNLCLHPEV
SKERKGTVVDEKCRRMTNGQAKRKLEEDPEANVELCEYHENLYNIEVEDYLPKGVFSFEK
LLKYCEEKTLCPYFIVRRMISLCNIIIYSYHYLLDPKIAERVSNEVSKDSIVIFDEAHNI
DNVCIESLSLDLTTDALRRATRGANALDERISEVRKVDSQKLQDEYEKLVQGLHSADILT
DQEEPFVETPVLPQDLLTEAIPGNIRRAEHFVSFLKRLIEYLKTRMKVLHVISETPKSFL
QHLKQLTFIERKPLRFCSERLSLLVRTLEVTEVEDFTALKDIATFATLISTYEEGFLLII
EPYEIENAAVPNPIMRFTCLDASIAIKPVFERFSSVIITSGTISPLDMYPRMLNFKTVLQ
KSYAMTLAKKSFLPMIITKGSDQVAISSRFEIRNDPSIVRNYGSMLVEFAKITPDGMVVF
FPSYLYMESIVSMWQTMGILDEVWKHKLILVETPDAQETSLALETYRKACSNGRGAILLS
VARGKVSEGIDFDHQYGRTVLMIGIPFQYTESRILKARLEFMRENYRIRENDFLSFDAMR
HAAQCLGRVLRGKDDYGVMVLADRRFSRKRSQLPKWIAQGLSDADLNLSTDMAISNTKQF
LRTMAQPTDPKDQEGVSVWSYEDLIKHQNSRKDQGGFIENENKEGEQDEDEDEDIEMQ
Sequence of entity 3 (3), FASTA
>9PB7_3 RNA polymerase II transcription factor B subunit 3 (chains 3)
MLMDEYEENKDMCPICKTDRYLSPDVKFLVNPECYHRICESCVDRIFSLGPAQCPYKGCD
KILRKNKFKTQIFDDVEVEKEVDIRKRVFNVFNKTIDDFNGDLVEYNKYLEEVEDIIYKL
DHGIDVAKTEEKLRTYEELNKQLIMNNLERSRTEIESFEQRQKFEKEMKLKKRLLERQIE
EEERMNKEWTKKEIVNRLSTTTQDINETIEGVKNTVKLKKSSARRKLEELNRVLKNNPYF
NSNVNVQNSRLKDAVPFTPFNGDREAHPRFTLKGSVYNDPFIKDLEHRKEFIASGFNTNY
AYERVLTEAFMGLGCVISEEL
Sequence of entity 4 (7), FASTA
>9PB7_4 General transcription and DNA repair factor IIH helicase subunit XPB (chains 7)
MTDVEGYQPKSKGKIFPDMGESFFSSDEDSPATDAEIDENYDDNRETSEGRGERDTGAMV
TGLKKPRKKTKSSRHTAADSSMNQMDAKDKALLQDTNSDIPADFVPDSVSGMFRSHDFSY
LRLRPDHASRPLWISPSDGRIILESFSPLAEQAQDFLVTIAEPISRPSHIHEYKITAYSL
YAAVSVGLETDDIISVLDRLSKVPVAESIINFIKGATISYGKVKLVIKHNRYFVETTQAD
ILQMLLNDSVIGPLRIDSDHQVQPPEDVLQQQLQQTAGKPATNVNPNDVEAVFSAVIGGD
NEREEEDDDIDAVHSFEIANESVEVVKKRCQEIDYPVLEEYDFRNDHRNPDLDIDLKPST
QIRPYQEKSLSKMFGNGRARSGIIVLPCGAGKTLVGITAACTIKKSVIVLCTSSVSVMQW
RQQFLQWCTLQPENCAVFTSDNKEMFQTESGLVVSTYSMVANTRNRSHDSQKVMDFLTGR
EWGFIILDEVHVVPAAMFRRVVSTIAAHAKLGLTATLVREDDKIGDLNFLIGPKLYEANW
MELSQKGHIANVQCAEVWCPMTAEFYQEYLRETARKRMLLYIMNPTKFQACQFLIQYHER
RGDKIIVFSDNVYALQEYALKMGKPFIYGSTPQQERMNILQNFQYNDQINTIFLSKVGDT
SIDLPEATCLIQISSHYGSRRQEAQRLGRILRAKRRNDEGFNAFFYSLVSKDTQEMYYST
KRQAFLVDQGYAFKVITHLHGMENIPNLAYASPRERRELLQEVLLKNEEAAGIEVGDDAD
NSVGRGSNGHKRFKSKAVRGEGSLSGLAGGEDMAYMEYSTNKNKELKEHHPLIRKMYYKN
LKK
Sequence of entity 5 (8), FASTA
>9PB7_5 SWI/SNF chromatin-remodeling complex subunit SNF5 (chains 8)
MNNQPQGTNSVPNSIGNIFSNIGTPSFNMAQIPQQLYQSLTPQQLQMIQQRHQQLLRSRL
QQQQQQQQQTSPPPQTHQSPPPPPQQSQPIANQSATSTPPPPPAPHNLHPQIGQVPLAPA
PINLPPQIAQLPLATQQQVLNKLRQQAIAKNNPQVVNAITVAQQQVQRQIEQQKGQQTAQ
TQLEQQRQLLVQQQQQQQLRNQIQRQQQQQFRHHVQIQQQQQKQQQQQQQHQQQQQQQQQ
QQQQQQQQQQQQQQQQQQQQQQQQQQQQGQIPQSQQVPQVRSMSGQPPTNVQPTIGQLPQ
LPKLNLPKYQTIQYDPPETKLPYPTYWSDKKADTDTLLYEQIIQRDKINKYSLIRETNGY
DPFSIYGFSNKEYISRLWHTLKYYQDLKNTRMKSITSTSQKIPSASIWGNGYSGYGNGIT
NTTTRVIPQVEVGNRKHYLEDKLKVYKQAMNETSEQLVPIRLEFDQDRDRFFLRDTLLWN
KNDKLIKIEDFVDDMLRDYRFEDATREQHIDTICQSIQEQIQEFQGNPYIELNQDRLGGD
DLRIRIKLDIVVGQNQLIDQFEWDISNSDNCPEEFAESMCQELELPGEFVTAIAHSIREQ
VHMYHKSLALLGYNFDGSAIEDDDIRSRMLPTITLDDVYRPAAESKIFTPNLLQISAAEL
ERLDKDKDRDTRRKRRQGRSNRRGMLALSGTSASNTSMNGVHNTVAAGNASSLPPGEILL
PDIADIPRTFRTPVPSTLMPGGVDVGPSVESYELRNTTTYKSRPDRPKPVSPPCYIIDHI
PGHSLLLSIKLPGKVNTKEEFAAAPNDTSSGTNAMLPSPESLKTKLNSNIRAGVTIPSIP
NPIANHTVTNSPNPTLQPVIPGGAASKSVPTPSLPIAPPVAPHDSEATLLTNSNNGSSNN
NTQNT
Sequence of entity 6 (9), FASTA
>9PB7_6 Transcription initiation factor TFIID subunit 14 (chains 9)
MVATVKRTIRIKTQQHILPEVPPVENFPVRQWSIEIVLLDDEGKEIPATIFDKVIYHLHP
TFANPNRTFTDPPFRIEEQGWGGFPLDISVFLLEKAGERKIPHDLNFLQESYEVEHVIQI
PLNKPLLTEELAKSGSTEETTANTGTIGKRRTTTNTTAEPKAKRAKTGSASTVKGSVDLE
KLAFGLTKLNEDDLVGVVQMVTDNKTPEMNVTNNVEEGEFIIDLYSLPEGLLKSLWDYVK
KNTE
Sequence of entity 7 (N), FASTA
>9PB7_7 promoter DNA (chains N)
GATGAGTACTTTACTTGTTATCAGAT
Sequence of entity 8 (T), FASTA
>9PB7_8 promoter DNA (chains T)
ATCTGATAACAAGTAAAGTACTCATC
Sequence of entity 9 (4), FASTA
>9PB7_9 General transcription and DNA repair factor IIH subunit TFB4 (chains 4)
MDAISDPTFKHARSRKQVTEESPSLLTVIIEIAPKLWTTFDEEGNEKGSIIKVLEALIVF
LNAHLAFNSANKVAVIAAYSQGIKYLYPESTSALKASESENKTRSDLKIINSDMYRRFRN
VDETLVEEIYKLFELEKKQIEQNSQRSTLAGAMSAGLTYVNRISKESVTTSLKSRLLVLT
CGSGSSKDEIFQYIPIMNCIFSATKMKCPIDVVKIGGSKESTFLQQTTDATNGVYLHVES
TEGLIQYLATAMFIDPSLRPIIVKPNHGSVDFRTSCYLTGRVVAVGFICSVCLCVLSIIP
PGNKCPACDSQFDEHVIAKLKRKPVVPRLKAKKKVTKP
Sequence of entity 10 (6), FASTA
>9PB7_10 General transcription and DNA repair factor IIH subunit SSL1 (chains 6)
MAPVVISESEEDEDRVAITRRTKRQVHFDGEGDDRVDQQQQQHSSSHRDRDKHVQRKKKK
RLSNRNLQGSNGGYAWEDEIKRSWDLVKVDDEGDMASLVASIVEARKKRTAKKNITPYQR
GIIRSLILTLDCSEAMLEKDLRPNRHAMIIQYAIDFVHEFFDQNPISQMGIIIMRNGLAQ
LVSQVSGNPQDHIDALKSIRKQEPKGNPSLQNALEMARGLLLPVPAHCTREVLIVFGSLS
TTDPGDIHQTIDSLVSEKIRVKVLGLSAQVAICKELCKATNYGDESFYKILLDETHLKEL
FNEAVTPLPVNKINKGFTLVKMGFPTRIFEDTPTFCSCHSKLVYGGYFCPNCHSKVCSLP
TVCPCCDLMLILSTHLARSYHHLMPLKTFAEVPTTEKFRSEDCFSCQSRFPILKNHKNGK
LLTSSRYRCEDCKQEFCVDCDVFIHEILHNCPGCESKPVIT
Sequence of entity 11 (1), FASTA
>9PB7_11 General transcription and DNA repair factor IIH subunit TFB1 (chains 1)
MSHSGAAIFEKVSGIIAINEDVSPAELTWRSTDGDKVHTVVLSTIDKLQATPASSEKMML
RLIGKVDESKKRKDNEGNEVVPKPQRHMFSFNNRTVMDNIKMTLQQIISRYKDADIYEEK
RRREESAQHTETPMSSSSVTAGTPTPHLDTPQLNNGAPLINTAKLDDSLSKEKLLTNLKL
QQSLLKGNKVLMKVFQETVINAGLPPSEFWSTRIPLLRAFALSTSQKVGPYNVLSTIKPV
ASSENKVNVNLSREKILNIFENYPIVKKAYTDNVPKNFKEPEFWARFFSSKLFRKLRGEK
IMQNDRGDVIIDRYLTLDQEFDRKDDDMLLHPVKKIIDLDGNIQDDPVVRGNRPDFTMQP
GVDINGNSDGTVDILKGMNRLSEKMIMALKNEYSRTNLQNKSNITNDEEDEDNDERNELK
IDDLNESYKTNYAIIHLKRNAHEKTTDNDAKSSADSIKNADLKVSNQQMLQQLSLVMDNL
INKLDLNQVVPNNEVSNKINKRVITAIKINAKQAKHNNVNSALGSFVDNTSQANELEVKS
TLPIDLLESCRMLHTTCCEFLKHFYIHFQSGEQKQASTVKKLYNHLKDCIEKLNELFQDV
LNGDGESMSNTCTAYLKPVLNSITLATHKYDEYFNEYNNNSN
Sequence of entity 12 (2), FASTA
>9PB7_12 General transcription and DNA repair factor IIH subunit TFB2 (chains 2)
MSDYSLKHSVTQYLEEIPQQVQNRLYTSPATCLAIYRILPPLAKFFIMAMVFNENEVPLL
DLDKWVNSNGKLQFQNAIKSMKSLHLLIPNKSSGTLMINLNPTFKISLRNALTGGEVQNS
FGVVVEENVVSLDLLDEYSANKWETILHFMVGTPLAKIPSEKVLNLLKHSKLMEEVNSTG
EFKITNEGFQFLLQEINSQLWTLLLQYLKMIETSKMDLVDVLHFIFMLGALEVGKAYKID
ALSETQRIMLQDMRDYGLVFQKHSNDSIFYPTKLALMLTSDTKTIRSASNAMDSVLRQNR
EEPSVNEDGANGKSTTDITTSDDLNKAGLKNQDIPDGSLIVETNFKIYSYSNSPLQIAVL
SLFVHLKARFVNMVLGQITRESIRRALTNGITADQIIAYLETHAHPQMRRLAEEKLEKKL
ELDPNCKEPLQVLPPTVVDQIRLWQLELDRVITYEGSLYSDFETSQEYNLLSKYAQDIGV
LLWKDDKKKKFFISKEGNSQVLDFAKRKLKKKQ
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| ZN | Zinc ion | Zn | 7 |
| SF4 | Iron/sulfur cluster | Fe4 S4 | 1 |
Primary citation
Structure of TFIIH of PIC-Med-SWI/SNF. Yang, C., Nagai, S., Chen, D.-H. To be published.
Other PDB entries of the same protein (UniProt Q3E7C1 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 3DGP 1.8 Å, Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2
- 3DOM 2.6 Å, Crystal Structure of the complex between Tfb5 and the C-terminal domain of Tfb2
- 7O4J 2.9 Å, Yeast RNA polymerase II transcription pre-initiation complex (consensus)
- 7ML0 3.0 Å, RNA polymerase II pre-initiation complex (PIC1)
- 8CEN 3.0 Å, Yeast RNA polymerase II transcription pre-initiation complex with core Mediator
- 7ML4 3.1 Å, RNA polymerase II initially transcribing complex (ITC)
- 7ZS9 3.1 Å, Yeast RNA polymerase II transcription pre-initiation complex with the +1 nucleosome…
- 7O4I 3.2 Å, Yeast RNA polymerase II transcription pre-initiation complex with initial transcription…
- 7O75 3.2 Å, Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA
- 7ML2 3.4 Å, RNA polymerase II pre-initiation complex (PIC3)
- 7O4L 3.4 Å, Yeast TFIIH in the expanded state within the pre-initiation complex
- 7O72 3.4 Å, Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA
Browse structure collections
About this viewer
MolViewer shows 9PB7 directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.