9Q2M: 60S ribosomal protein L19

Rabbit ribosomal 80S elongation complex with eEF2, partial P site Ala-tRNA, E site Ala-tRNA on NediV ORF. Determined by electron microscopy at 3.3 Å resolution. Released 17 Jun 2026.

Method: Electron microscopy
Resolution: 3.3 Å
Organisms: Oryctolagus cuniculus, Nedicistrovirus TFN-2012
Chains: 84
Atoms: 216,625
Mol. weight: 3217.06 kDa
Ligands: MG, ZN
Released: 17 Jun 2026

Explore 9Q2M in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

9Q2M contains 567 α-helices and 574 β-strands across 77 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain a: 8 helices, 7 β-strands

Element	Residues	Length	Sheet
α-helix	3-5	3
α-helix	7-10	4
α-helix	42-48	7
β-strand	72-73	2	67
α-helix	78-80	3
α-helix	84-92	9
β-strand	97-98	2	156
β-strand	100-102	3	68
α-helix	103-106	4
β-strand	110-111	2	67
α-helix	116-118	3
β-strand	122-126	5	68
β-strand	128-129	2	67
α-helix	131-140	10
β-strand	142-146	5	68

Chain A: 9 helices, 17 β-strands

Element	Residues	Length	Sheet
α-helix	3-5	3
α-helix	6-10	5
α-helix	14-16	3
α-helix	28-32	5
α-helix	34-37	4
β-strand	40-49	10	83
α-helix	57	1
β-strand	58-64	7	83
β-strand	71-77	7	83
β-strand	79	1	84
β-strand	83	1	85
β-strand	87-91	5	83
β-strand	100-103	4	83
β-strand	112-114	3	83
β-strand	116	1	86
β-strand	126	1	86
β-strand	134-140	7	83
α-helix	142-144	3
β-strand	145-149	5	83
β-strand	155-159	5	83
β-strand	163-166	4	83
α-helix	168	1
β-strand	169	1	84
α-helix	182-190	9
β-strand	224-225	2	87
β-strand	237-238	2	87

Chain aa: 5 helices, 6 β-strands

Element	Residues	Length	Sheet
β-strand	20-22	3	140
β-strand	28	1	111
β-strand	29-31	3	140
β-strand	36-43	8	141
α-helix	49-55	7
β-strand	57	1	110
α-helix	63-65	3
β-strand	66-73	8	141
α-helix	75-80	6
α-helix	89-92	4
α-helix	96-99	4

Chain AA: 6 helices, 9 β-strands

Element	Residues	Length	Sheet
α-helix	15-21	7
β-strand	25	1	35
β-strand	38	1	36
β-strand	48	1	35
β-strand	49	1	36
α-helix	52-67	16
α-helix	71-73	3
β-strand	74-78	5	37
α-helix	81-94	14
β-strand	97-100	4	37
β-strand	121-124	4	37
α-helix	131-139	9
β-strand	144-148	5	37
β-strand	159-162	4	37
α-helix	168-186	19

Chain b: 6 helices, 0 β-strands

Element	Residues	Length
α-helix	12-19	8
α-helix	22-24	3
α-helix	37-49	13
α-helix	54-75	22
α-helix	91-100	10
α-helix	102-116	15

Chain B: 14 helices, 22 β-strands

Element	Residues	Length	Sheet
α-helix	9-10	2
α-helix	14-16	3
α-helix	32-35	4
α-helix	40-41	2
β-strand	42-43	2	91
β-strand	45-54	10	92
β-strand	57-59	3	93
β-strand	71-73	3	93
β-strand	76-80	5	92
α-helix	82-83	2
β-strand	84-94	11	94
β-strand	99-106	8	94
α-helix	112-117	6
α-helix	134-138	5
α-helix	140-156	17
β-strand	159-165	7	94
β-strand	180-184	5	94
β-strand	185-186	2	91
α-helix	190-200	11
β-strand	204-205	2	94
α-helix	207-210	4
β-strand	215-222	8	92
α-helix	223-225	3
β-strand	227-229	3	95
α-helix	231-235	5
α-helix	237-240	4
β-strand	270-272	3	95
β-strand	276-286	11	92
β-strand	292-293	2	96
β-strand	298-299	2	96
β-strand	320	1	97
β-strand	324	1	97
β-strand	330-335	6	92
β-strand	344-349	6	92
β-strand	365-367	3	93
α-helix	382-389	8

Chain bb: 3 helices, 6 β-strands

Element	Residues	Length	Sheet
α-helix	12-16	5
β-strand	32-36	5	148
β-strand	44-47	4	148
β-strand	54-55	2	149
β-strand	62-65	4	149
α-helix	71	1
β-strand	72-73	2	149
α-helix	74	1
β-strand	78-82	5	148

Chain BB: 8 helices, 10 β-strands

Element	Residues	Length	Sheet
α-helix	24-27	4
β-strand	28-34	7	41
β-strand	43-50	8	41
α-helix	58-63	6
β-strand	66-70	5	41
α-helix	71-74	4
β-strand	82-90	9	41
β-strand	95-105	11	41
α-helix	107-113	7
β-strand	120-128	9	41
β-strand	134-142	9	41
β-strand	143	1	42
α-helix	158-176	19
α-helix	181-188	8
α-helix	192-201	10
β-strand	207	1	42
β-strand	211-217	7	41
α-helix	225-231	7

69 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
60S ribosomal protein L19	R	protein	180	Oryctolagus cuniculus	G1TYL6 (AlphaFold model)
uL24	W	protein	106	Oryctolagus cuniculus
18S rRNA	9	RNA	1670	Oryctolagus cuniculus
40S_SA_C domain-containing protein	AA	protein	217	Oryctolagus cuniculus	G1TJH8 (AlphaFold model)
40S ribosomal protein S3a	BB	protein	213	Oryctolagus cuniculus	G1SS70 (AlphaFold model)
40S ribosomal protein S2	CC	protein	221	Oryctolagus cuniculus	O18789 (AlphaFold model)
40S ribosomal protein S4	EE	protein	262	Oryctolagus cuniculus	G1TA47
40S ribosomal protein S6	GG	protein	237	Oryctolagus cuniculus	G1TM55
Small ribosomal subunit protein eS7	HH	protein	189	Oryctolagus cuniculus	G1SVB0
40S ribosomal protein S8	II	protein	206	Oryctolagus cuniculus	G1TJW1
40S ribosomal protein S9	JJ	protein	185	Oryctolagus cuniculus	B7NZS8
Small ribosomal subunit protein uS17	LL	protein	151	Oryctolagus cuniculus	G1TRM4

72 more molecules are not listed.

Sequence of entity 1 (R), FASTA

>9Q2M_1 60S ribosomal protein L19 (chains R)
SMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLIIRKPVTVHSRA
RCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMRILRRLLRRYRESKKIDRHMYH
SLYLKVKGNVFKNKRILMEHIHKLKADKARKKLLADQAEARRSKTKEARKRREERLQAKK

Sequence of entity 2 (W), FASTA

>9Q2M_2 uL24 (chains W)
MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHK
KGQQRAITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQA

Sequence of entity 3 (9), FASTA

>9Q2M_3 18S rRNA (chains 9)
UACCUGGUUGAUCCUGCCAGUAGCAUAUGCUUGUCUCAAAGAUUAAGCCAUGCAUGUCUA
AGUACGCACGGCCGGUACAGUGAAACUGCGAAUGGCUCAUUAAAUCAGUUAUGGUUCCUU
UGGUCGCUCGACUUGGAUAACUGUGGUAAUUCUAGAGCUAAUACAUGCCGACGGGCGCUC
GUGCAUUUAUCAGUGGUGACUCUAGAUAACCUCGGGCCGAUCGCACGCGGCGGCGACGAC
CCAUUCGAACGUCUGCCCUAUCAACUUUCGAUGGUAGUCGCCGUGCCUACCAUGGUGACC
ACGGGUGACGGGGAAUCAGGGUUCGAUUCCGGAGAGGGAGCCUGAGAAACGGCUACCACA
UCCAAGGAAGGCAGCAGGCGCGCAAAUUACCCACUCCCGACCCGGGGAGGUAGUGACGAA
AAAUAACAAUACAGGACUCUUUCGAGGCCCUGUAAUUGGAAUGAGUCCACUUUAAAUCCU
UUAACGAGGAUCCAUUGGAGGGCAAGUCUGGUGCCAGCAGCCGCGGUAAUUCCAGCUCCA
AUAGCGUAUAUUAAAGUUGCUGCAGUUAAAAAGCUCGUAGUUGGAUCUUGGGAGCGGCCG
UCCCCUGCUCGGCGGGCCCGAAGCGUUUACUUUGAAAAAAUUAGAGUGUUCAAAGCAGGC
CGCCUGGAUACCGCAGCUAGGAAUAAUGGAAUAGGACCGCGGUUCUAUUUUGUUGGUUUU
CGGAACUGAGGCCAUGAUUAAGAGGGACGGCCGGGGGCAUUCGUAUUGCGCCGCUAGAGG
UGAAAUUCUUGGACCGGCGCAAGACGGACCAGAGCGAAAGCAUUUGCCAAGAAUGUUUUC
AUUAAUCAAGAACGAAAGUCGGAGGUUCGAAGACGAUCAGAUACCGUCGUAGUUCCGACC
AUAAACGAUGCCGACUGGCGAUGCGGCGGCGUUAUUCCCAUGACCCGCCGGGCAGCUUCC
GGGAAACCAAAGUCUUUGGGUUCCGGGGGGAGUAUGGUUGCAAAGCUGAAACUUAAAGGA
AUUGUGUACACACCGCCCGUCGCUACUACCGAUUGGAUGGUUUAGUGAGGCCCUCGGAUC
GGCCCCGCCGGGGGCCCUGGCGGAGCGCUGAGAAGACGGUCGAACUUGACUAUCUAGAGG
AAGUAAAAGUCGUAACAAGGUUUCCGUAGGUGAACCUGCGGAAGGAUCAUUAACGGAAGG
GCACCACCAGGAGUGGAGCCUGCGGCUUAAUUUGACUCAACACGGGAAACCUCACCCGGC
CCGGACACGGACAGGAUUGACAGAUUGAUAGCUCUUUCUCGAUUCCGUGGGUGGUGGUGC
AUGGCCGUUCUUAGUUGGUGGAGCGAUUUGUCUGGUUAAUUCCGAUAACGAACGAGACUC
UGGCAUGCUAACUAGUUACGCGACCCCGGUCGGCGUAACUUCUUAGAGGGACAAGUGGCG
UUCAGCCACCCGAGAUUGAGCAAUAACAGGUCUGUGAUGCCCUUAGAUGUCCGGGGCUGC
ACGCGCGCUACACUGACUGGCUCAGCGUGUGCCUACCCUACGCCGGCAGGCGCGGGUAAC
CCGUUGAACCCCAUUCGUGAUGGGGAUCGGGGAUUGCAAUUAUUCCCCAUGAACGAGGAA
UUCCCAGUAAGUGCGGGUCAUAAGCUUGCGUUGAUUAAGUCCCUGCCCUU

Sequence of entity 4 (AA), FASTA

>9Q2M_4 40S_SA_C domain-containing protein (chains AA)
SGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLA
ARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAGRFTPGTFTNQIQTAFREPRL
LVVTDPRADHQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLARE
VLRMRGTISREHPWEVMPDLYFYRDPEEIEKEEQAAA

Sequence of entity 5 (BB), FASTA

>9Q2M_5 40S ribosomal protein S3a (chains BB)
VVDPFSKKDWYDVKAPAMFNIRNIGKTLVTRTQGTKIASDGLKGRVFEVSLADLQNDEVA
FRKFKLITEDVQGKNCLTNFHGMDLTRDKMCSMVKKWQTMIEAHVDVKTTDGYLLRLFCV
GFTKKRNNQIRKTSYAQHQQVRQIRKKMMEIMTREVQTNDLKEVVNKLIPDSIGKDIEKA
CQSIYPLHDVFVRKVKMLKKPKFELGKLMELHG

Sequence of entity 6 (CC), FASTA

>9Q2M_6 40S ribosomal protein S2 (chains CC)
KEWLPVTKLGRLVKDMKIKSLEEIYLFSLPIKESEIIDFFLGASLKDEVLKIMPVQKQTR
AGQRTRFKAFVAIGDYNGHVGLGVKCSKEVATAIRGAIILAKLSIVPVRRGYWGNKIGKP
HTVPCKVTGRCGSVLVRLIPAPRGTGIVSAPVPKKLLMMAGIDDCYTSARGCTATLGNFA
KATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDHLVKTHT

Sequence of entity 7 (EE), FASTA

>9Q2M_7 40S ribosomal protein S4 (chains EE)
ARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDEV
KKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAKY
KLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNLC
MVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRG
KGIRLTIAEERDKRLAAKQSSG

Sequence of entity 8 (GG), FASTA

>9Q2M_8 40S ribosomal protein S6 (chains GG)
MKLNISFPATGCQKLIEVDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQG
FPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKRKSVRGCIVDANLSVLNLVIVKKGEKD
IPGLTDTTVPRRLGPKRASRIRKLFNLSKEDDVRQYVVRKPLNKEGKKPRTKAPKIQRLV
TPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSL

Sequence of entity 9 (HH), FASTA

>9Q2M_9 Small ribosomal subunit protein eS7 (chains HH)
AKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVP
VPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAV
HDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDV
NFEFPEFQL

Sequence of entity 10 (II), FASTA

>9Q2M_10 40S ribosomal protein S8 (chains II)
GISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLD
VGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPL
GRKKGAKLTPEEEEILNKKRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQ
CGRADGYVLEGKELEFYLRKIKARKG

Sequence of entity 11 (JJ), FASTA

>9Q2M_11 40S ribosomal protein S9 (chains JJ)
PVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELL
TLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAK
SIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKG
QGGAG

Sequence of entity 12 (LL), FASTA

>9Q2M_12 Small ribosomal subunit protein uS17 (chains LL)
DIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKCPF
TGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDVQI
GDIVTVGECRPLSKTVRFNVLKVTKAAGTKK

Ligands and cofactors

ID	Name	Formula	Copies
MG	Magnesium ion	Mg	206
ZN	Zinc ion	Zn	8

Primary citation

Structural studies of nedicistrovirus IRES-driven, initiation factor-independent translation shed light on key steps of eukaryotic translation elongation. De, S., Altomare, C.G., Abaeva, I.S. et al. Nucleic Acids Res (2026) 54. DOI 10.1093/nar/gkag510 · PubMed

Other PDB entries of the same protein (UniProt G1TYL6 (AlphaFold model), which also has an AlphaFold model), best resolution first:

9MR4 2.65 Å, NAC: Ribosome nascent chain complex(Oxa1L)
9RHU 2.65 Å, Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop codon in mutated F2A…
8RJD 2.79 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
8B6C 2.79 Å, Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative…
7UCK 2.8 Å, 80S translation initiation complex with ac4c(-1) mRNA and Harringtonine
9BDL 2.8 Å, 80S ribosome with angiogenin
8B5L 2.86 Å, Cryo-EM structure of ribosome-Sec61-TRAP (TRanslocon Associated Protein) translocon…
9Q7Q 2.86 Å, ABCE1-eRF1-rnc-AMD1C
7TOR 2.9 Å, Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20
8P2K 2.9 Å, Ternary complex of translating ribosome, NAC and METAP1
9Q1S 3.0 Å, NediV IRES (P site) in complex with Rabbit 80S ribosome
9Q2P 3.0 Å, Rabbit ribosomal 80S elongation complex with eEF1A, A*/T Ala-tRNA, P site Ala-tRNA, E…

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