9RHU: Rabbit 80S ribosome
Rabbit 80S ribosome in complex with eRF1-AAQ, stalled at the Stop codon in mutated F2A sequence. Determined by electron microscopy at 2.65 Å resolution. Released 21 Jan 2026.
- Method
- Electron microscopy
- Resolution
- 2.65 Å
- Organisms
- Oryctolagus cuniculus, Homo sapiens, Foot-and-mouth disease virus SAT 2
- Chains
- 88
- Atoms
- 233,632
- Mol. weight
- 4184.11 kDa
- Ligands
- SF4, GTP, SPD, ZN
- Released
- 21 Jan 2026
Explore 9RHU in 3D
Show helices and sheets
RCSB PDB
PDBe
Secondary structure: helices and β-sheets
9RHU contains 653 α-helices and 626 β-strands across 81 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.
Chain a1: 11 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 13-15 | 3 | |
| β-strand | 16-17 | 2 | 61 |
| β-strand | 20-21 | 2 | 61 |
| α-helix | 22-27 | 6 | |
| α-helix | 30-34 | 5 | |
| α-helix | 39-47 | 9 | |
| α-helix | 51-65 | 15 | |
| α-helix | 72-75 | 4 | |
| β-strand | 76-78 | 3 | 62 |
| β-strand | 84 | 1 | 63 |
| α-helix | 87-89 | 3 | |
| β-strand | 93-97 | 5 | 62 |
| β-strand | 102-106 | 5 | 62 |
| α-helix | 109-111 | 3 | |
| β-strand | 115 | 1 | 63 |
| α-helix | 116-118 | 3 | |
| α-helix | 124-126 | 3 | |
| α-helix | 133-138 | 6 | |
Chain a2: 7 helices, 4 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 21-22 | 2 | |
| α-helix | 58-60 | 3 | |
| α-helix | 61-63 | 3 | |
| β-strand | 69 | 1 | 70 |
| β-strand | 75-79 | 5 | 70 |
| α-helix | 82-85 | 4 | |
| α-helix | 86-88 | 3 | |
| β-strand | 95-99 | 5 | 70 |
| α-helix | 105-118 | 14 | |
| α-helix | 120-121 | 2 | |
| β-strand | 122 | 1 | 70 |
Chain A2: 16 helices, 12 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 42-47 | 6 | |
| β-strand | 51-53 | 3 | 11 |
| β-strand | 56-57 | 2 | 11 |
| α-helix | 61-68 | 8 | |
| α-helix | 76-78 | 3 | |
| α-helix | 81-84 | 4 | |
| β-strand | 94-98 | 5 | 12 |
| β-strand | 107-111 | 5 | 12 |
| α-helix | 114-116 | 3 | |
| α-helix | 124-129 | 6 | |
| α-helix | 136-138 | 3 | |
| α-helix | 140-142 | 3 | |
| β-strand | 151-155 | 5 | 13 |
| β-strand | 163 | 1 | 14 |
| β-strand | 164-170 | 7 | 13 |
| α-helix | 175 | 1 | |
| β-strand | 176-179 | 4 | 13 |
| α-helix | 182-185 | 4 | |
| β-strand | 190-192 | 3 | 13 |
| α-helix | 194-196 | 3 | |
| β-strand | 197-203 | 7 | 13 |
| α-helix | 217-220 | 4 | |
| α-helix | 222-223 | 2 | |
| α-helix | 241-243 | 3 | |
| α-helix | 247-265 | 19 | |
| α-helix | 270-275 | 6 | |
| β-strand | 277 | 1 | 14 |
| β-strand | 280 | 1 | 15 |
Chain b1: 10 helices, 5 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 9-16 | 8 | 87 |
| β-strand | 19-27 | 9 | 87 |
| β-strand | 31-34 | 4 | 87 |
| β-strand | 37-38 | 2 | 87 |
| α-helix | 39-41 | 3 | |
| α-helix | 44 | 1 | |
| α-helix | 45-47 | 3 | |
| α-helix | 48-58 | 11 | |
| β-strand | 66-73 | 8 | 87 |
| α-helix | 77-95 | 19 | |
| α-helix | 96-100 | 5 | |
| α-helix | 102-115 | 14 | |
| α-helix | 117-119 | 3 | |
| α-helix | 127-131 | 5 | |
| α-helix | 141-143 | 3 | |
Chain B1: 4 helices, 6 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 12-17 | 6 | |
| β-strand | 32-36 | 5 | 23 |
| β-strand | 43-47 | 5 | 23 |
| β-strand | 54-55 | 2 | 24 |
| β-strand | 62-65 | 4 | 24 |
| α-helix | 71 | 1 | |
| β-strand | 72-73 | 2 | 24 |
| α-helix | 74 | 1 | |
| β-strand | 78-81 | 4 | 23 |
| α-helix | 82-83 | 2 | |
Chain b2: 3 helices, 7 β-strands
| Element | Residues | Length | Sheet |
|---|
| β-strand | 4 | 1 | 15 |
| β-strand | 6-16 | 11 | 95 |
| β-strand | 21-30 | 10 | 95 |
| α-helix | 36-40 | 5 | |
| β-strand | 46-59 | 14 | 95 |
| β-strand | 62-78 | 17 | 95 |
| β-strand | 83-88 | 6 | 95 |
| α-helix | 91-93 | 3 | |
| α-helix | 94-96 | 3 | |
| β-strand | 100-104 | 5 | 95 |
Chain B2: 14 helices, 11 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 24-77 | 54 | |
| β-strand | 80-82 | 3 | 29 |
| α-helix | 83-86 | 4 | |
| β-strand | 88-93 | 6 | 30 |
| α-helix | 102-110 | 9 | |
| β-strand | 118-123 | 6 | 30 |
| α-helix | 126-134 | 9 | |
| α-helix | 136-138 | 3 | |
| β-strand | 139-142 | 4 | 30 |
| α-helix | 146-156 | 11 | |
| β-strand | 158-161 | 4 | 31 |
| β-strand | 164-167 | 4 | 31 |
| α-helix | 172-178 | 7 | |
| α-helix | 179-181 | 3 | |
| α-helix | 186-195 | 10 | |
| α-helix | 200-206 | 7 | |
| β-strand | 207 | 1 | 31 |
| α-helix | 208-209 | 2 | |
| β-strand | 210-211 | 2 | 30 |
| α-helix | 214-215 | 2 | |
| β-strand | 225 | 1 | 32 |
| β-strand | 232 | 1 | 32 |
| β-strand | 233-234 | 2 | 30 |
| α-helix | 236-238 | 3 | |
| α-helix | 239-246 | 8 | |
Chain c1: 7 helices, 3 β-strands
| Element | Residues | Length | Sheet |
|---|
| α-helix | 7-19 | 13 | |
| α-helix | 28-38 | 11 | |
| β-strand | 39-40 | 2 | 86 |
| α-helix | 44-63 | 20 | |
| α-helix | 72-82 | 11 | |
| β-strand | 96-98 | 3 | 107 |
| α-helix | 100-108 | 9 | |
| β-strand | 117-119 | 3 | 107 |
| α-helix | 120-123 | 4 | |
| α-helix | 130-131 | 2 | |
73 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.
Molecules and chains
| Molecule | Chains | Type | Length | Organism | UniProt |
|---|
| 60S ribosomal protein L34 | MB | protein | 117 | Oryctolagus cuniculus | G1TXG5 (AlphaFold model) |
| 18S rRNA | A1 | RNA | 1870 | Oryctolagus cuniculus | |
| 60S ribosomal protein L6 | A2 | protein | 291 | Oryctolagus cuniculus | G1SKF7 (AlphaFold model) |
| 28S rRNA | A3 | RNA | 4808 | Oryctolagus cuniculus | |
| Small ribosomal subunit protein eS27 | B1 | protein | 84 | Oryctolagus cuniculus | G1TZ76 (AlphaFold model) |
| 60S ribosomal protein L7 | B2 | protein | 249 | Oryctolagus cuniculus | G1SV32 (AlphaFold model) |
| 5S rRNA | B3 | RNA | 119 | Oryctolagus cuniculus | |
| Small ribosomal subunit protein eS28 | C1 | protein | 69 | Oryctolagus cuniculus | G1TIB4 |
| Large ribosomal subunit protein eL8 | C2 | protein | 319 | Oryctolagus cuniculus | G1STW0 |
| 5.8S rRNA | C3 | RNA | 158 | Oryctolagus cuniculus | |
| Ubiquitin-ribosomal protein eS31 fusion protein | D1 | protein | 80 | Oryctolagus cuniculus | G1SK22 |
| 60S ribosomal protein L9 | D2 | protein | 192 | Oryctolagus cuniculus | G1SWI6 |
76 more molecules are not listed.
Sequence of entity 1 (MB), FASTA
>9RHU_1 60S ribosomal protein L34 (chains MB)
MVQRLTYRRRLSYNTASNKTRLSRTPGNRIVYLYTKKVGKAPKSACGVCPGRLRGVRAVR
PKVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQKAK
Sequence of entity 2 (A1), FASTA
>9RHU_2 18S rRNA (chains A1)
UACCUGGUUGAUCCUGCCAGUAGCAUAUGCUUGUCUCAAAGAUUAAGCCAUGCAUGUCUA
AGUACGCACGGCCGGUACAGUGAAACUGCGAAUGGCUCAUUAAAUCAGUUAUGGUUCCUU
UGGUCGCUCGCUCCUCUCCUACUUGGAUAACUGUGGUAAUUCUAGAGCUAAUACAUGCCG
ACGGGCGCUGACCCCCUUCGCGGGGGGGAUGCGUGCAUUUAUCAGAUCAAAACCAACCCG
GUCAGCCUCCCCCCGGCCCCGGCCGGGGGGGUGGGCGCCGGCGGCUUUGGUGACUCUAGA
UAACCUCGGGCCGAUCGCACGCCCUCCGUGGCGGCGACGACCCAUUCGAACGUCUGCCCU
AUCAACUUUCGAUGGUAGUCGCCGUGCCUACCAUGGUGACCACGGGUGACGGGGAAUCAG
GGUUCGAUUCCGGAGAGGGAGCCUGAGAAACGGCUACCACAUCCAAGGAAGGCAGCAGGC
GCGCAAAUUACCCACUCCCGACCCGGGGAGGUAGUGACGAAAAAUAACAAUACAGGACUC
UUUCGAGGCCCUGUAAUUGGAAUGAGUCCACUUUAAAUCCUUUAACGAGGAUCCAUUGGA
GGGCAAGUCUGGUGCCAGCAGCCGCGGUAAUUCCAGCUCCAAUAGCGUAUAUUAAAGUUG
CUGCAGUUAAAAAGCUCGUAGUUGGAUCUUGGGAGCGGGCGGGCGGUCCGCCGCGAGGCG
AGCCACCGCCCGUCCCCGCCCCUUGCCUCUCGGCGCCCCCUCGAUGCUCUUAGCUGAGUG
UCCCGCGGGGCCCGAAGCGUUUACUUUGAAAAAAUUAGAGUGUUCAAAGCAGGCCCGAGC
CGCCUGGAUACCGCAGCUAGGAAUAAUGGAAUAGGACCGCGGUUCUAUUUUGUUGGUUUU
CGGAACUGAGGCCAUGAUUAAGAGGGACGGCCGGGGGCAUUCGUAUUGCGCCGCUAGAGG
UGAAAUUCUUGGACCGGCGCAAGACGGACCAGAGCGAAAGCAUUUGCCAAGAAUGUUUUC
AUUAAUCAAGAACGAAAGUCGGAGGUUCGAAGACGAUCAGAUACCGUCGUAGUUCCGACC
AUAAACGAUGCCGACUGGCGAUGCGGCGGCGUUAUUCCCAUGACCCGCCGGGCAGCUUCC
GGGAAACCAAAGUCUUUGGGUUCCGGGGGGAGUAUGGUUGCAAAGCUGAAACUUAAAGGA
AUUGACGGAAGGGCACCACCAGGAGUGGAGCCUGCGGCUUAAUUUGACXCAACACGGGAA
ACCUCACCCGGCCCGGACACGGACAGGAUUGACAGAUUGAUAGCUCUUUCUCGAUUCCGU
GGGUGGUGGUGCAUGGCNGUUCUUAGUUGGUGGAGCGAUUUGUCUGGUUAAUUCCGAUAA
CGAACGAGACUCUGGCAUGCUAACUAGUUACGCGACCCCCGAGCGGUCGGCGUCCCCCAA
CUUCUUAGAGGGACAAGUGGCGUUCAGCCACCCGAGAUUGAGCAAUAACAGGUCUGUGAU
GCCCUUAGAUGUCCGGGGCUGCACGCGCGCUACACUGACUGGCUCAGCGUGUGCCUACCC
UACGCCGGCAGGCGCGGGUAACCCGUUGAACCCCAUUCGUGAUGGGGAUCGGGGAUUGCA
AUUAUUCCCCAUGAACGAGGAAUUCCCAGUAAGUGCGGGUCAUAAGCUUGCGUUGAUUAA
GUCCCUGCCCUUUGUACACACCGCCCGUCGCUACUACCGAUUGGAUGGUUUAGUGAGGCC
CUCGGAUCGGCCCCGCCGGGGUCGGCCCACGGCCCUGGCGGAGCGCUGAGAAGACGGUCG
AACUUGACUAUCUAGAGGAAGUAAAAGUCGUAACAAGGUUUCNGUAGGUGAACCUGCGGA
AGGAUCAUUA
Sequence of entity 3 (A2), FASTA
>9RHU_3 60S ribosomal protein L6 (chains A2)
MAGEKAPAAKPDATKKSPAKKADHARGKAKKKTLAEKKPKKGKPHCSRNPVLVRGIGRYS
RSAMYSRKALYKRKYAAPKSRIERKKKREKVLATVTKPVGGDKNGGTRVVKLRKMPRYYP
TEDVPRKLLSHGKKPFSQHVRKLRASITPGTILIILTGRHRGKRVVFLKQLSSGLLLVTG
PLSLNRVPLRRTHQKFVIATSTKIDISGVKIPKHLTDAYFKKKKLRKPRHQEGEIFDTEK
EKYEITEQRKVDQKAVDSQILPKIKAVPQLQGYLRSVFALTNGVYPHKLVF
Sequence of entity 4 (A3), FASTA
>9RHU_4 28S rRNA (chains A3)
CGCGACCUCAGAUCAGACGUGGCGACCCGCUGAAUUUAAGCAUAUUAGUCAGCGGAGGAA
AAGAAACUAACCAGGAUUCCCUCAGUAACGGCGAGUGAACAGGGAAGAGCCCAGCGCCGA
AUCCCCGCCCCGCGGUGGGGCGCGGGAAAUGUGGCGUACGGAAGACCCACUCCCCGGCGC
CGCUCGUGGGGGGCCCAAGUCCUUCUGAUCGAGGCCCAGCCCGUGGACGGUGUGAGGCCG
GUAGCGGCCCCCGGCGCGCCGGGCCCGGGUCUUCCCGGAGUCGGGUUGCUUGGGAAUGCA
GCCCAAAGCGGGUGGUAAACUCCAUCUAAGGCUAAAUACCGGCACGAGACCGAUAGUCAA
CAAGUACCGUAAGGGAAAGUUGAAAAGAACUUUGAAGAGAGAGUUCAAGAGGGCGUGAAA
CCGUUAAGAGGUAAACGGGUGGGGUCCGCGCAGUCCGCCCGGAGGAUUCAACCCGGCGGC
GUGGUCCGGCCGUGCCGGCGGUCUCGGCGGAUCUUUCCCGCUCCCCGUUCCUCCCGACCC
CUCCACCCGCUCCCCCUCCCCCGCCGGUCUUCUCCCUUCACGGGGGGUGGGUCGGCGGGU
GCGGGGGUGGGCGGGCGGGGCCGGGGGUGGGGUCGGCGGGGGACCGCCCCCCGGCCGGCG
ACCGGCCGCCGCCGGGCGCAUUUCCACCGCGGCGGUGCGCCGCGACCGGCUCCGGGACGG
CUGGGAAGGCCCCGGCGGGGAAGGUGGCCCGGGGGGACGCCUCGCCGCCGUCGUCCGCGG
CGGCGGCGGGCGCGACCCCUCCCCGGGUGUUACAGCCCCGCCCCGGCAGCAGCAGCUCGC
CGAAUCCCGGGGCCGAGGGAGCGAGACCUGUGUCGCCGCGCUCUCCCCCCUCCCGGCGCU
CCCCCCCGCGGGGGUCCCCCGCGAGGGGGCUCCCCCCGCGGGGGCGCGCCGGUGUCGCCG
CCCUCGCGGGCGCGGCACGGGGGGGCCGGGCCGCCCCUCCCACGGCGCGACCGCUCUCCC
GGCCCCCGCCGCCGCCUCUUCGGGCGUGCGGCGGGGGUGGGGCGGACUGUCCCCAGUGCG
CCCCGGGCGUGUCACGCCGUCGGGCUCGGGGGAGAAGUCGGCCACGGCGCGUCGCGCGCC
UCCGCGUCCCCCCCUCGCCGUCUCCGGGCGGCGGGGGGGGGUUUCGGCGCGGUGUUCUCG
GCGCGCGCGCGCGAGCGAGCGCACGGGGUCGGCGGCGAUGUCGGCUACCCACCCGACCCG
UCUUGAAACACGGACCAAGGAGUCUAACACGUGCGCGAGUCGGGGGCUCGCACGAAAGCC
GCCGUGGCGCAAUGAAGGUGAAGGCCGGCGGCGGCUUCCCGCCGUCGUCGGCCGAGGUGG
GAUCCCGAGGCCCUUCCAGUCCGCCGAGGGCGCACCACCGGCCCGUCUCGCCCGCCGCGC
CGGGGAGGUGGAGCACGAGCGCACGUGUUAGGACCCGAAAGAUGGUGAACUAUGCCUGGG
CAGGGCGAAGCCAGAGGAAACUCUGGUGGAGGUCCGUAGCGGUCCUGACGUGCAAAUCGG
UCGUCCGACCUGGGUAUAGGGGCGAAAGACUAAUCGAACCAUCUAGUAGCUGGUUCCCUC
CGAAGUUUCCCUCAGGAUAGCUGGCGCUCUCGCAACCCCGCAGUUUUAUCCGGUAAAGCG
AAUGAUUAGAGGUCUUGGGGCCGAAACGAUCUCAACCUAUUCUCAAACUUUAAAUGGGUA
AGAAGCCCGGCUCGCUGGCGUGGAGCCGGGCGUGGAAUGCGAGUGCCUAGUGGGCCACUU
UUGGUAAGCAGAACUGGCGCUGCGGGAUGAACCGAACGCCGGGUUAAGGCGCCCGAUGCC
GACGCUCAUCAGACCCCAGAAAAGGUGUUGGUUGAUAUAGACAGCAGGACGGUGGCCAUG
GAAGUCGGAAUCCGCUAAGGAGUGUGUAACAACUCACCUGCCGAAUCAACUAGCCCUGAA
AAUGGAUGGCGCUGGAGCGUCGGGCCCAUACCCGGCCGUCGCUGGCAGUCGGCAGAGCGA
GAAAGAGAGUGGAGCGCGCCGCGGGACUCCCCCCGCGGGGGUCCCCGGCCACCCCCCCCC
CGCGGACGCUACGCCGCGACGAGUAGGAGGGCCGCUGCGGUGAGCCUUGAAGCCUAGGGC
GCGGGCCCGGGUGGAGCCGCCGCAGGUGCAGAUCUUGGUGGUAGUAGCAAAUAUUCAAAC
GAGAACUUUGAAGGCCGAAGUGGAGAAGGGUUCCAUGUGAACAGCAGUUGAACAUGGGUC
AGUCGGUCCUGAGAGAUGGGCGAGCGCCGUUCCGAAGGGACGGGCGAUGGCCUCCGUUGC
CCUCAGCCGAUCGAAAGGGAGUCGGGUUCAGAUCCCCGAAUCCGGAGUGGCGGAGAUGGG
CGCCGCGAGGCGUCCAGUGCGGUAACGCGACCGAUCCCGGAGAAGCCGGCGGGAGCCCCG
GGGAGAGUUCUCUUUUCUUUGUGAAGGGCAGGGCGCCCUGGAAUGGGUUCGCCCCGAGAG
AGGGGCCCGUGCCUUGGAAAGCGUCGCGGUUCCGGCGGCGUCCGGUGAGCUCUCGCUGGC
CCUUGAAAAUCCGGGGGAGAGGGUGUAAAUCUCGCGCCGGGCCGUACCCAUAUCCGCAGC
AGGUCUCCAAGGUGAACAGCCUCUGGCAUGUUGGAACAAUGUAGGUAAGGGAAGUCGGCA
AGCCGGAUCCGUAACUUCGGGAUAAGGAUUGGCUCUAAGGGCUGGGUCGGUCGGGCUGGG
GCGCGAAGCGGGGCUGGGCGCGCGCCGCGGCUGGACGAGGCGCCGCCGCCCCCCCCACGC
CCGGGGCGCCCUCCCCCGGCCGGGUCCGCUCCCUCGCGCGCGCGUGCGCCGUGGCGCGCG
CCGCGCGCGCGGCCGAGCCCCGUCUCCCUCCCCCCCUCUCCCCUCCCGGGGCGGGGUGCG
GGGAGGGGCGGGCGGGGCCGUCGCUCGCCGCGCGUGCGCGUCGCUGCGCGUGCGCCGCGC
GGGGGGUCCGGCGGGCCUCCGGACGGGGGCUCCGGGCACCCGGGCACCCGGGGGGCCGGC
GGCGGCGGCGACUCUGGACGCGAGCCGGGCCCUUCCCGUGGAUCGCCCCAGCUGCGGCGG
GCGUCGCGGCCGCCCUCGGGGAGCCCGGCGGGCGCCGCGUGCGCGCGCGUGCGCGCCCGG
GGUCGGGGGGGUGCGAGGCAGGGGAGGCCCUCUCUCCUCCUCCCCCACCCCGGCGCCGCG
GCGCCGCGCGUGCGCGCGCGGUCUCCCCCCGCCGGGUCCGCCCCCGGGGCCGCGGUUCCG
CGCGGCGCCUCGCCUCGGCCGGCGCCUAGCAGCCGACUUAGAACUGGUGCGGACCAGGGG
AAUCCGACUGUUUAAUUAAAACAAAGCAUCGCGAAGGCCCGCGGCGGGUGUUGACGCGAU
GUGAUUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAAAUUCAAUGAAGCGCGGGUAAA
CGGCGGGAGUAACUAUGACUCUCUUAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGAC
GCGCAUGAAXGGAUGAACGAGAUUCCCACUGUCCCUACCUACUAUCCAGCGAAACCACAG
CCAAGGGAACGGGCUUGGCGGAAUCAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUA
GUCUGGCACGGUGAAGAGACAUGAGAGGUGUAGAAUAAGUGGGAGGCCCCCGGCGCCCUC
CCGCCCCCGCGAGGGGGCGGGGCGGGGUCCGCCGGCCUUGCGGGCCGCCGGUGAAAUACC
ACUACUCUUAUCGUUUUUUCACUGACCCGGUGAGGCGGGGGGGCGAGCCCCGAGGGGCUC
UCGCUUCUGGCGCCAAGCGCCGGGCCCCGUCGGUCCGCGCGGGCCGGCGGCGGCCGGGCG
CGACCCGCUCCGGGGACAGUGCCAGGUGGGGAGUUUGACUGGGGCGGUACACCUGUCAAA
CGGUAACGCAGGUGUCCUAAGGCGAGCUCAGGGAGGACAGAAACCUCCCGUGGAGCAGAA
GGGCAAAAGCUCGCUUGAUCUUGAUUUUCAGUACGAAUACAGACCGUGAAAGCGGGGCCU
CACGAUCCUUCUGAGCUUUUGGGUUUUAAGCAGGAGGUGUCAGAAAAGUUACCACAGGGA
UAACUGGCUUGUGGCGGCCAAGCGUUCAUAGCGACGUCGCUUUUUGAUCCUUCGAUGUCG
GCUCUUCCUAUCAUUGUGAAGCAGAAUUCACCAAGCGUUGGAUUGUUCACCCACUAAUAG
GGAACGUGAGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCCUACUGAUGAUGU
GUUGUUGCCAUGGUAAUCCUGCUCAGUACGAGAGGAACCGCAGGUUCAGACAUUUGGUGU
AUGUGCUUGGCUGAGGAGCCAAUGGGGCGAAGCUACCAUCUGUGGGAUUAUGACUGAACG
CCUCUAAGUCAGAAUCCCGCCCAGGCGGAACGAUACGGCAGCGCCGAAGGAGCCUCGGUU
GGCCUCGGAUAGCCGGUCCCCCGCCGUCCCCGCCGGCGGCCCGCGUCGUGCGUCCGCCUC
GGCGGCGUGCGGCGCGCCCCCCGCCGCGCGUCGGGACCGGGGUCCGGUGCGGAGAGCCCU
UCGUCCCGGGAAAUGGGGCGCGGCCGGAAAGGGGGCCGCCCUCUCGCCCGUCACGCACCG
CACGUUCGUGGGGAACCUGGCGCUAAACCAUUCGUAGACGACCUGCUUCUGGGUCGGGGU
UUCGUACGUAGCAGAGCAGCUCCCUCGCUGCGAUCUAUUGAAAGUCAGCCCUCGACACAA
GGGUUUGU
Sequence of entity 5 (B1), FASTA
>9RHU_5 Small ribosomal subunit protein eS27 (chains B1)
MPLAKDLLHPSPEEEKRKHKKKRLVQSPNSYFMDVKCPGCYKITTVFSHAQTVVLCVGCS
TVLCQPTGGKARLTEGCSFRRKQH
Sequence of entity 6 (B2), FASTA
>9RHU_6 60S ribosomal protein L7 (chains B2)
LFANNIREKKKVPAVPETLKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHK
EYRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFN
GTFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNTLIARSL
GKYNIICMEDLIHEIYTVGKHFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQ
INRLIRRMN
Sequence of entity 7 (B3), FASTA
>9RHU_7 5S rRNA (chains B3)
UCUACGGCCAUACCACCCUGAACGCGCCCGAUCUCGUCUGAUCUCGGAAGCUAAGCAGGG
UCGGGCCUGGUUAGUACUUGGAUGGGAGACCGCCUGGGAAUACCGGGUGCUGUAGGCUU
Sequence of entity 8 (C1), FASTA
>9RHU_8 Small ribosomal subunit protein eS28 (chains C1)
MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLE
SEREARRLR
Sequence of entity 9 (C2), FASTA
>9RHU_9 Large ribosomal subunit protein eL8 (chains C2)
MSSYRLGYCMKEERHNLVLCLWSQSPGILNSKCLWPFTNIHLLVGALPREGAGGAWGGGR
SEQLPTCSTTHHDFTWDKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQR
AILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGD
VPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCILKGK
ARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSV
ARIAKLEKAKAKELATKLG
Sequence of entity 10 (C3), FASTA
>9RHU_10 5.8S rRNA (chains C3)
CGACUCUUAGCGGUGGAUCACUCGGCUCGUGCGUCGAUGAAGAACGCAGCUAGCUGCGAG
AAUUAAUGUGAAUUGCAGGACACAUUGAUCAUCGACACUUCGAACGCACUUGCGGCCCCG
GGUUCCUCCCGGGGCUACGCCUGUCUGAGCGUCGCUUG
Sequence of entity 11 (D1), FASTA
>9RHU_11 Ubiquitin-ribosomal protein eS31 fusion protein (chains D1)
AKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMASHF
DRHYCGKCCLTYCFNKPEDK
Sequence of entity 12 (D2), FASTA
>9RHU_12 60S ribosomal protein L9 (chains D2)
MKTILSNQTVDIPENVDISLKGRTVIVKGPRGTLRRDFNHINVELSLLGKKKKRLRVDKW
WGNRKELATVRTICSHVQNMIKGVTLGFRYKMRSVYAHFPINVVIQENGSLVEIRNFLGE
KYIRRVRMRPGVACSVSQAQKDELVLEGNDIELVSNSAALIQQATTVKNKDIRKFLDGIY
VSEKGTVQQADE
Ligands and cofactors
| ID | Name | Formula | Copies |
|---|
| SF4 | Iron/sulfur cluster | Fe4 S4 | 2 |
| GTP | Guanosine-5'-triphosphate | C10 H16 N5 O14 P3 | 1 |
| SPD | Spermidine | C7 H19 N3 | 2 |
| ZN | Zinc ion | Zn | 8 |
| MG | Magnesium ion | Mg | 367 |
Water and common crystallization additives (K) are not listed.
Primary citation
Molecular architecture and diversity of StopGo/2A translational recoding. Li, X., Zuber, P.K., Loughran, G. et al. Proc Natl Acad Sci U S A (2026) 123:e2528667123-e2528667123. DOI 10.1073/pnas.2528667123 · PubMed
Other PDB entries of the same protein (UniProt G1TXG5 (AlphaFold model), which also has an AlphaFold model), best resolution first:
- 7O7Y 2.2 Å, Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a…
- 7OYD 2.3 Å, Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b
- 11IQ 2.4 Å, Rabbit 80S with eEF2,eIF5A and SERBP1
- 7O7Z 2.4 Å, Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a…
- 8SCB 2.5 Å, Terminating ribosome with SRI-41315
- 9MR4 2.65 Å, NAC: Ribosome nascent chain complex(Oxa1L)
- 8RJB 2.69 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
- 8VVQ 2.7 Å, Codon sampling state of elongation inhibitor-treated mammalian ribosomes obtained from…
- 8RJD 2.79 Å, Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in…
- 8B6C 2.79 Å, Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative…
- 6SGC 2.8 Å, Rabbit 80S ribosome stalled on a poly(A) tail
- 7OBR 2.8 Å, RNC-SRP early complex
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