9VVM: Transmembrane protein

Name: PDB 9VVM: CryoEM structure of a transmembrane protein
Published: 2026-07-22
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: membrane protein

CryoEM structure of a transmembrane protein. Determined by electron microscopy at 3.38 Å resolution. Released 22 Jul 2026.

Method: Electron microscopy
Resolution: 3.38 Å
Organism: Homo sapiens
Chains: 1
Atoms: 5,250
Mol. weight: 82.52 kDa
Ligands: NAD
Released: 22 Jul 2026

Explore 9VVM in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

9VVM contains 26 α-helices and 24 β-strands across 1 chain. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 26 helices, 24 β-strands

Element	Residues	Length	Sheet
α-helix	42-45	4
α-helix	47-65	19
α-helix	67-69	3
α-helix	70-74	5
α-helix	79-108	30
α-helix	111-132	22
α-helix	139-171	33
α-helix	177-208	32
α-helix	217-237	21
α-helix	244-247	4
α-helix	251-269	19
α-helix	280-284	5
α-helix	290-303	14
α-helix	304-306	3
α-helix	309-316	8
α-helix	323-328	6
β-strand	331	1	1
α-helix	344-346	3
α-helix	347-358	12
α-helix	359-363	5
α-helix	364-370	7
α-helix	378-404	27
α-helix	406-407	2
β-strand	413-420	8	2
β-strand	426-431	6	3
β-strand	437-443	7	3
β-strand	448	1	2
β-strand	453-456	4	2
β-strand	461-470	10	3
β-strand	473-482	10	3
β-strand	485-491	7	2
β-strand	492-494	3	4
β-strand	497-499	3	4
β-strand	502-505	4	2
β-strand	516-521	6	5
β-strand	527-529	3	6
β-strand	537-539	3	6
β-strand	544-545	2	5
β-strand	549-550	2	5
β-strand	554-555	2	7
β-strand	559-563	5	6
β-strand	567-570	4	6
β-strand	574-575	2	7
β-strand	580-588	9	5
β-strand	592-601	10	5
β-strand	607	1	1
α-helix	608-611	4
α-helix	612-636	25
α-helix	642-666	25
α-helix	671-694	24

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Solute carrier family 15 member 2	A	protein	729	Homo sapiens	Q16348 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>9VVM_1 Solute carrier family 15 member 2 (chains A)
MNPFQKNESKETLFSPVSIEEVPPRPPSPPKKPSPTICGSNYPLSIAFIVVNEFCERFSY
YGMKAVLILYFLYFLHWNEDTSTSIYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLV
YVLGHVIKSLGALPILGGQVVHTVLSLIGLSLIALGTGGIKPCVAAFGGDQFEEKHAEER
TRYFSVFYLSINAGSLISTFITPMLRGDVQCFGEDCYALAFGVPGLLMVIALVVFAMGSK
IYNKPPPEGNIVAQVFKCIWFAISNRFKNRSGDIPKRQHWLDWAAEKYPKQLIMDVKALT
RVLFLYIPLPMFWALLDQQGSRWTLQAIRMNRNLGFFVLQPDQMQVLNPLLVLIFIPLFD
FVIYRLVSKCGINFSSLRKMAVGMILACLAFAVAAAVEIKINEMAPAQPGPQEVFLQVLN
LADDEVKVTVVGNENNSLLIESIKSFQKTPHYSKLHLKTKSQDFHFHLKYHNLSLYTEHS
VQEKNWYSLVIREDGNSISSMMVKDTESRTTNGMTTVRFVNTLHKDVNISLSTDTSLNVG
EDYGVSAYRTVQRGEYPAVHCRTEDKNFSLNLGLLDFGAAYLFVITNNTNQGLQAWKIED
IPANKMSIAWQLPQYALVTAGEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTIAVGNIIV
LVVAQFSGLVQWAEFILFSCLLLVICLIFSIMGYYYVPVKTEDMRGPADKHIPHIQGNMI
KLETKKTKL

Ligands and cofactors

ID	Name	Formula	Copies
NAD	Nicotinamide-adenine-dinucleotide	C21 H27 N7 O14 P2	1

Primary citation

CryoEM structure of a transmembrane protein. Ning, Y., Ge, J. To be published.

Other PDB entries of the same protein (UniProt Q16348 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6EZI 1.5 Å, PDZK1 domain 4 in complex with C-terminal peptide of human PepT2.
9UDC 3.38 Å, Cryo-EM Structure of SLC15A2 with NAD+ (Pose 1)
7PMY 3.8 Å, HsPepT2 bound to Ala-Phe in the inward facing partially occluded conformation

Browse structure collections

About this viewer

MolViewer shows 9VVM directly in your browser with nothing to install. Switch between cartoon, ball-and-stick, spacefill and surface views, color by chain, secondary structure or B-factor, measure distances, angles and dihedrals, and share or embed the view.