G0SFB5: Ribosome biogenesis protein YTM1 (YTM1)

Ribosome biogenesis protein YTM1 (YTM1) is a 495-residue protein from Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: G0SFB5.

Gene
YTM1
Organism
Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
Length
495 residues
Mean pLDDT
90.0
Model
AF-G0SFB5-F1 v6
Model created
1 Aug 2025
PDB structures
10

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Model confidence (pLDDT)

The mean pLDDT of this model is 90.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate75%
70 to 90Confident: backbone generally right16%
50 to 70Low: treat with caution7%
Below 50Very low: often disordered regions3%

What pLDDT means and how to read it

Function

Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome

Subunit structure

Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. The complex is held together by ERB1, which interacts with NOP7 via its N-terminal domain and with YTM1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome (PubMed:26476442, PubMed:26657628). Interacts (via UBL domain) with MDN1 (via…

Subcellular location

Nucleus, nucleolus, Nucleus, nucleoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
6QTBX-ray1.89 ÅB/E=8-98
5CXBX-ray2.1 ÅA=1-495
8PV2EM2.63 ÅCD=1-495
5EM2X-ray2.67 ÅB/D=1-495
8I9ZEM2.7 ÅCD=1-495
8IA0EM2.7 ÅCD=1-495
8I9XEM2.8 ÅCD=1-495
5CYKX-ray3.0 ÅA=1-495
5CXCX-ray3.1 ÅA=1-495
8I9YEM3.1 ÅCD=1-495

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