G5E5A3: EF-hand calcium binding domain 6 (EFCAB6)

EF-hand calcium binding domain 6 (EFCAB6) is a 294-residue protein from Bos taurus. This is its AlphaFold structure prediction, created 31 Mar 2025. UniProt accession: G5E5A3.

Gene
EFCAB6
Organism
Bos taurus
Length
294 residues
Mean pLDDT
65.3
Model
AF-G5E5A3-F1 v6
Model created
31 Mar 2025
PDB structures
3

Explore in 3D Color by confidence AlphaFold DB UniProt

Model confidence (pLDDT)

The mean pLDDT of this model is 65.3 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate15%
70 to 90Confident: backbone generally right40%
50 to 70Low: treat with caution12%
Below 50Very low: often disordered regions34%

What pLDDT means and how to read it

Function

Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex. Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating

Subunit structure

Microtubule inner protein component of sperm flagellar doublet microtubules. Binds PARK7. Part of a ternary complex containing PARK7, EFCAB6/DJBP and AR

Subcellular location

Cell projection, cilium, flagellum, Cytoplasm, cytoskeleton, cilium axoneme, Nucleus

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
9CPBEM3.52 Å3H=88-1497
8OTZEM3.6 Å3/y/z=1223-1497
9FQREM5.0 Å3/5/Fm/Gq/Xa/Xb/y/z=1-1497

More AlphaFold highlights

About this viewer

MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.