AH receptor-interacting protein (AIP) is a 330-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O00170.
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The mean pLDDT of this model is 90.9 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 77% |
| 70 to 90 | Confident: backbone generally right | 16% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting
Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4APO | X-ray | 1.9 Å | A/B=166-330 |
| 4AIF | X-ray | 2.01 Å | A/B=172-315 |
| 8QMO | EM | 2.76 Å | C=1-330 |
| 7ZUB | EM | 2.85 Å | C=1-330 |
| 2LKN | NMR | A=2-166 |
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