Cytohesin-3 (Cyth3) is a 399-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O08967.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 84.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 49% |
| 70 to 90 | Confident: backbone generally right | 37% |
| 50 to 70 | Low: treat with caution | 10% |
| Below 50 | Very low: often disordered regions | 4% |
What pLDDT means and how to read it
Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF factors through replacement of GDP with GTP (PubMed:18042453). Plays a role in the epithelial polarization (PubMed:20080746)
Interacts with TAMALIN. Interacts with FRMD4A (PubMed:20080746). Interacts with FRMD4B (PubMed:20080746)
Cytoplasm, cytosol, Cell membrane, Cell junction, adherens junction, Cell junction, tight junction
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1FGY | X-ray | 1.5 Å | A=261-387 |
| 1U2B | X-ray | 1.8 Å | A=261-387 |
| 1FHW | X-ray | 1.9 Å | A/B=264-391 |
| 2R09 | X-ray | 1.9 Å | A/B=63-399 |
| 2R0D | X-ray | 2.04 Å | A/B=63-399 |
| 1FGZ | X-ray | 2.05 Å | A=261-387 |
| 1FHX | X-ray | 2.5 Å | A/B=264-391 |
| 6BBP | EM | 35.0 Å | A=63-399 |
| 6BBQ | EM | 35.0 Å | A=63-399 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.