CENP-A recruiting complex protein mis19 (mis19) is a 112-residue protein from Schizosaccharomyces pombe (strain 972 / ATCC 24843). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: O42995.
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The mean pLDDT of this model is 67.3 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 12% |
| 70 to 90 | Confident: backbone generally right | 28% |
| 50 to 70 | Low: treat with caution | 39% |
| Below 50 | Very low: often disordered regions | 21% |
What pLDDT means and how to read it
Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A (PubMed:24774534, PubMed:24789708, PubMed:25375240). Links mis16 and mis18 to recruit CENP-A through interacting with non-sense-mediated mRNA decay (NMD) factors and the SWI/SNF complex (PubMed:24774534). Also links mis18 with the CCAN/mis6/ctf19 complex to promote CENP-A assembly (PubMed:24789708)
Component of the CENP-A recruiting complex composed of at least mis16, mis19, mis19 and mis20 (PubMed:24774534, PubMed:24789708, PubMed:25375240)
Chromosome, centromere, Chromosome, centromere, kinetochore
Compare the prediction with experimentally determined structures of the same protein:
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