Proenkephalin-B (PDYN) is a 254-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P01213.
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The mean pLDDT of this model is 58.7 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 2% |
| 70 to 90 | Confident: backbone generally right | 20% |
| 50 to 70 | Low: treat with caution | 43% |
| Below 50 | Very low: often disordered regions | 35% |
What pLDDT means and how to read it
Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity)
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 8VJU | X-ray | 1.99 Å | C=207-219 |
| 8VJV | X-ray | 2.12 Å | D=207-214 |
| 9L60 | EM | 2.9 Å | P=207-219 |
| 9CCE | X-ray | 3.15 Å | C/D=207-223 |
| 8F7W | EM | 3.19 Å | P=207-214 |
| 7Y1F | EM | 3.3 Å | F=207-219 |
| 9CCF | X-ray | 4.0 Å | A/B=207-223 |
| 2N2F | NMR | A=207-219 |
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