Guanine nucleotide-binding protein G(T) subunit gamma-T1 (GNGT1) is a 74-residue protein from Bos taurus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P02698.
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The mean pLDDT of this model is 88.7 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 65% |
| 70 to 90 | Confident: backbone generally right | 23% |
| 50 to 70 | Low: treat with caution | 12% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction
G proteins are composed of 3 units, alpha, beta and gamma
Cell membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5KDO | X-ray | 1.9 Å | G=1-74 |
| 1GOT | X-ray | 2.0 Å | G=2-66 |
| 1TBG | X-ray | 2.1 Å | E/F/G/H=2-68 |
| 6B20 | X-ray | 2.34 Å | C/D=7-66 |
| 2TRC | X-ray | 2.4 Å | G=1-68 |
| 1A0R | X-ray | 2.8 Å | G=2-66 |
| 1B9X | X-ray | 3.0 Å | B=1-68 |
| 1B9Y | X-ray | 3.0 Å | B=1-68 |
| 7O7F | EM | 3.15 Å | G=1-74 |
| 8P12 | EM | 3.21 Å | G=1-74 |
| 6OYA | EM | 3.3 Å | G=2-74 |
| 6OY9 | EM | 3.9 Å | G=2-74 |
| 6QNO | EM | 4.38 Å | G=1-74 |
| 9EPR | EM | 4.9 Å | G=1-74 |
| 8P13 | EM | 5.2 Å | G=1-74 |
| 8P15 | EM | 5.9 Å | G=1-74 |
| 1MF6 | NMR | A=60-71 |
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