P04387: Galactose/lactose metabolism regulatory protein GAL80 (GAL80)

Galactose/lactose metabolism regulatory protein GAL80 (GAL80) is a 435-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P04387.

Gene
GAL80
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
435 residues
Mean pLDDT
91.6
Model
AF-P04387-F1 v6
Model created
1 Aug 2025
PDB structures
4

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Model confidence (pLDDT)

The mean pLDDT of this model is 91.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate82%
70 to 90Confident: backbone generally right9%
50 to 70Low: treat with caution4%
Below 50Very low: often disordered regions5%

What pLDDT means and how to read it

Function

This protein is a negative regulator for the gene expression of the lactose/galactose metabolic genes. It binds to GAL4 and so blocks transcriptional activation by it, in the absence of an inducing sugar

Subunit structure

Monomer

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
3BTVX-ray2.1 ÅA/B=1-435
3V2UX-ray2.1 ÅA/B=1-435
3BTSX-ray2.7 ÅA/B=1-435
3BTUX-ray2.85 ÅA/B/C/D/E/F=1-435

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