P05214: Tubulin alpha-3 chain (Tuba3a)

Tubulin alpha-3 chain (Tuba3a) is a 450-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P05214.

Gene

Tuba3a

Organism

Mus musculus

Length

450 residues

Mean pLDDT

91.6

Model

AF-P05214-F1 v6

Model created

1 Aug 2025

PDB structures

4

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Model confidence (pLDDT)

The mean pLDDT of this model is 91.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

What pLDDT means and how to read it

Function

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin

Subunit structure

Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13…

Subcellular location

Cytoplasm, cytoskeleton, Cytoplasm, cytoskeleton, flagellum axoneme

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

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