Prolactin receptor (Prlr) is a 610-residue protein from Rattus norvegicus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P05710.
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The mean pLDDT of this model is 61.6 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 29% |
| 70 to 90 | Confident: backbone generally right | 11% |
| 50 to 70 | Low: treat with caution | 13% |
| Below 50 | Very low: often disordered regions | 47% |
What pLDDT means and how to read it
This is a receptor for the anterior pituitary hormone prolactin
Interacts with SMARCA1. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent
Membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1F6F | X-ray | 2.3 Å | B/C=20-229 |
| 3NPZ | X-ray | 3.35 Å | B/C=20-229 |
| 3EW3 | X-ray | 3.8 Å | B/C=20-229 |
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