Growth-regulated alpha protein (CXCL1) is a 107-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P09341.
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The mean pLDDT of this model is 80.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 36% |
| 70 to 90 | Confident: backbone generally right | 39% |
| 50 to 70 | Low: treat with caution | 22% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 9EJC | EM | 2.98 Å | F=35-107 |
| 8K4O | EM | 3.01 Å | F=35-97 |
| 8XWV | EM | 3.07 Å | D/E=35-102 |
| 8XWA | EM | 3.48 Å | D/E=35-107 |
| 1MGS | NMR | A/B=35-107 | |
| 1MSG | NMR | A/B=35-106 | |
| 1MSH | NMR | A/B=35-106 | |
| 1ROD | NMR | A/B=40-62, A/B=89-107 |
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