Chaperone protein DnaK (dnaK) is a 638-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0A6Y8.
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The mean pLDDT of this model is 92.3 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 80% |
| 70 to 90 | Confident: backbone generally right | 14% |
| 50 to 70 | Low: treat with caution | 3% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock
In pull-down experiments interacts with CedA (PubMed:28818726)
Cytoplasm, Cell inner membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 4F01 | X-ray | 1.4 Å | A/B=389-607 |
| 7RAX | X-ray | 1.41 Å | A=2-393 |
| 4HY9 | X-ray | 1.55 Å | A/B=389-607 |
| 4JNF | X-ray | 1.62 Å | A=389-610 |
| 4EZP | X-ray | 1.65 Å | A/B=389-607 |
| 4EZX | X-ray | 1.7 Å | A/B=389-607 |
| 4HYB | X-ray | 1.7 Å | A/B=389-607 |
| 4R5K | X-ray | 1.75 Å | A/B=389-607 |
| 4EZN | X-ray | 1.8 Å | A/B=389-607 |
| 4EZW | X-ray | 1.8 Å | A/B/C/D=389-607 |
| 4JWC | X-ray | 1.8 Å | A/B=389-607 |
| 7KRU | X-ray | 1.82 Å | A/B=1-540 |
| 7N6M | X-ray | 1.82 Å | A=389-607 |
| 4EZY | X-ray | 1.85 Å | A=389-607 |
| 4E81 | X-ray | 1.9 Å | A/B=389-607 |
| 4EZO | X-ray | 1.9 Å | A/B=389-607 |
| 4EZR | X-ray | 1.9 Å | A=389-607 |
| 4EZS | X-ray | 1.9 Å | A=389-607 |
| 4EZU | X-ray | 1.9 Å | A=389-607 |
| 4JWI | X-ray | 1.9 Å | A/B=389-607 |
Showing 20 of 62 experimental structures (best resolution first).
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