Lipoprotein-releasing system transmembrane protein LolC (lolC) is a 399-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0ADC3.
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The mean pLDDT of this model is 87.1 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 52% |
| 70 to 90 | Confident: backbone generally right | 39% |
| 50 to 70 | Low: treat with caution | 8% |
| Below 50 | Very low: often disordered regions | 2% |
What pLDDT means and how to read it
Part of an ATP-dependent transport system LolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and of LolA
Cell inner membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5NAA | X-ray | 1.88 Å | A/B=48-266 |
| 6F3Z | X-ray | 2.0 Å | A/C=48-266 |
| 6F49 | X-ray | 2.02 Å | A/B/C/D=48-166, A/B/C/D=180-266 |
| 9RLC | EM | 2.8 Å | C=1-399 |
| 9XRO | EM | 2.88 Å | C=1-399 |
| 9RLJ | EM | 2.9 Å | C=1-399 |
| 9RLD | EM | 3.0 Å | C=1-399 |
| 9RLG | EM | 3.09 Å | C=1-399 |
| 9RLF | EM | 3.17 Å | C=1-399 |
| 9RLE | EM | 3.18 Å | C=1-399 |
| 9RLH | EM | 3.19 Å | C=1-399 |
| 7ARJ | EM | 3.2 Å | C=1-399 |
| 7ARL | EM | 3.2 Å | C=1-399 |
| 9RLK | EM | 3.29 Å | C=1-399 |
| 7ARH | EM | 3.3 Å | C=1-399 |
| 7ARI | EM | 3.4 Å | C=1-399 |
| 7MDY | EM | 3.5 Å | A=1-399 |
| 7V8L | EM | 3.5 Å | C=1-399 |
| 9GRC | EM | 3.5 Å | C=1-399 |
| 9GVK | EM | 3.5 Å | C=1-399 |
Showing 20 of 26 experimental structures (best resolution first).
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