Outer surface protein A (ospA) is a 273-residue protein from Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P0CL66.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 92.7 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 90% |
| 70 to 90 | Confident: backbone generally right | 2% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 7% |
What pLDDT means and how to read it
Induces host (human and mouse) cytokine release by monocyte cell lines via TLR2 and CD14; nonlipidated protein does not stimulate host cells (PubMed:10426995)
Cell outer membrane, Cell surface
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2I5V | X-ray | 1.1 Å | O=27-273 |
| 2G8C | X-ray | 1.15 Å | O=27-273 |
| 2I5Z | X-ray | 1.2 Å | O=27-273 |
| 6J48 | X-ray | 1.2 Å | O=27-273 |
| 2OYB | X-ray | 1.3 Å | O=27-273 |
| 2OL7 | X-ray | 1.35 Å | A/B=27-273 |
| 6KWV | X-ray | 1.37 Å | O=27-273 |
| 2PI3 | X-ray | 1.4 Å | O=27-273 |
| 6ICS | X-ray | 1.4 Å | O=27-273 |
| 6KT1 | X-ray | 1.43 Å | O=28-273 |
| 6KWU | X-ray | 1.43 Å | O=27-273 |
| 6J6E | X-ray | 1.5 Å | O=27-273 |
| 6LJY | X-ray | 1.5 Å | O=27-273 |
| 2OY7 | X-ray | 1.55 Å | A=27-273 |
| 2HKD | X-ray | 1.6 Å | A=27-273 |
| 2OL6 | X-ray | 1.6 Å | O=27-273 |
| 3AUM | X-ray | 1.6 Å | O=27-273 |
| 5B2A | X-ray | 1.6 Å | O=27-273 |
| 6J49 | X-ray | 1.6 Å | O=27-273 |
| 6J6C | X-ray | 1.6 Å | O=27-273 |
Showing 20 of 52 experimental structures (best resolution first).
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.