P20068: Neurotensin/neuromedin N (Nts)

Neurotensin/neuromedin N (Nts) is a 169-residue protein from Rattus norvegicus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P20068.

Gene
Nts
Organism
Rattus norvegicus
Length
169 residues
Mean pLDDT
64.6
Model
AF-P20068-F1 v6
Model created
1 Aug 2025
PDB structures
15

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Model confidence (pLDDT)

The mean pLDDT of this model is 64.6 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate0%
70 to 90Confident: backbone generally right34%
50 to 70Low: treat with caution53%
Below 50Very low: often disordered regions13%

What pLDDT means and how to read it

Function

Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle

Subunit structure

Interacts with NTSR1. Interacts with SORT1. Interacts with SORL1

Subcellular location

Secreted, Cytoplasmic vesicle, secretory vesicle

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8FMZEM2.59 ÅF=157-162
4XESX-ray2.6 ÅB=157-162
4BUOX-ray2.75 ÅC/D=157-162
4GRVX-ray2.8 ÅB=157-162
8FN1EM2.88 ÅF=157-162
8FN0EM2.89 ÅF=157-162
4XEEX-ray2.9 ÅB=157-162
3ZEVX-ray3.0 ÅC/D=157-162
4BV0X-ray3.1 ÅC/D=157-162
5T04X-ray3.3 ÅB=157-162
4BWBX-ray3.57 ÅC/D=157-162
7L0PEM4.1 ÅD=157-162
7L0REM4.2 ÅD=157-162
7L0QEM4.3 ÅD=157-162
7L0SEM4.5 ÅD=157-162

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