Ecotin (eco) is a 162-residue protein from Escherichia coli (strain K12). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P23827.
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The mean pLDDT of this model is 90.0 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 82% |
| 70 to 90 | Confident: backbone generally right | 4% |
| 50 to 70 | Low: treat with caution | 12% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. The strength of inhibition does not appear to be correlated with a particular protease specificity
Homodimer
Periplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1SLU | X-ray | 1.8 Å | A=21-162 |
| 1IFG | X-ray | 2.0 Å | A=26-162 |
| 1N8O | X-ray | 2.0 Å | E=21-162 |
| 1SLW | X-ray | 2.0 Å | A=21-162 |
| 1ECY | X-ray | 2.19 Å | A=21-162 |
| 1FI8 | X-ray | 2.2 Å | C/E=21-109, D/F=105-162 |
| 1SLX | X-ray | 2.2 Å | A=21-162 |
| 1XX9 | X-ray | 2.2 Å | C/D=21-162 |
| 1AZZ | X-ray | 2.3 Å | C/D=21-162 |
| 1EZS | X-ray | 2.3 Å | A/B=21-162 |
| 1SLV | X-ray | 2.3 Å | A=21-162 |
| 1EZU | X-ray | 2.4 Å | A/B=21-162 |
| 7PQN | X-ray | 2.4 Å | C/D=1-162 |
| 1ID5 | X-ray | 2.5 Å | I=21-162 |
| 1XXF | X-ray | 2.6 Å | C/D=21-162 |
| 1ECZ | X-ray | 2.68 Å | A/B=21-162 |
| 7CBK | X-ray | 2.7 Å | A/C=1-162 |
| 1P0S | X-ray | 2.8 Å | E=21-162 |
| 4NIY | X-ray | 2.84 Å | E/F/G/H=21-162 |
| 1XXD | X-ray | 2.91 Å | C/D=21-162 |
Showing 20 of 22 experimental structures (best resolution first).
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