Transcription factor IIIB 70 kDa subunit (BRF1) is a 596-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P29056.
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The mean pLDDT of this model is 71.8 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 31% |
| 70 to 90 | Confident: backbone generally right | 29% |
| 50 to 70 | Low: treat with caution | 20% |
| Below 50 | Very low: often disordered regions | 20% |
What pLDDT means and how to read it
General activator of RNA polymerase III transcription. Interacts with TBP. Binds to Pol III subunit C34 and to the TAU135 component of TFIIIC
TFIIIB comprises the TATA-binding protein (TBP), the B-related factor (BRF) and the B' component (TFC5)
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 1NGM | X-ray | 2.95 Å | B/F/J/N=437-506 |
| 6F40 | EM | 3.7 Å | V=1-596 |
| 8FFZ | EM | 3.8 Å | H=1-382, H=439-596 |
| 7Q5B | EM | 3.98 Å | Z=1-596 |
| 6EU0 | EM | 4.0 Å | Z=1-596 |
| 6CNB | EM | 4.1 Å | R=1-382, R=438-596 |
| 6CNC | EM | 4.1 Å | R=1-382, R=438-596 |
| 6F44 | EM | 4.2 Å | V=1-596 |
| 6F41 | EM | 4.3 Å | V=1-596 |
| 6CNF | EM | 4.5 Å | R=1-382, R=438-596 |
| 6CND | EM | 4.8 Å | R=1-382, R=438-596 |
| 6F42 | EM | 5.5 Å | V=1-596 |
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