6EU0: RNA Polymerase III open pre-initiation complex

Name: PDB 6EU0: RNA Polymerase III open pre-initiation complex (OC-PIC)
Published: 2018-01-17
License: https://creativecommons.org/publicdomain/zero/1.0/
Keywords: transcription

RNA Polymerase III open pre-initiation complex (OC-PIC). Determined by electron microscopy at 4.0 Å resolution. Released 17 Jan 2018.

Method: Electron microscopy
Resolution: 4.0 Å
Organisms: Saccharomyces cerevisiae (strain ATCC 204508 / S288c), Saccharomyces cerevisiae S288c
Chains: 22
Atoms: 48,918
Mol. weight: 899.6 kDa
Ligands: ZN, MG
Released: 17 Jan 2018

Explore 6EU0 in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6EU0 contains 224 α-helices and 259 β-strands across 20 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 57 helices, 66 β-strands

Element	Residues	Length	Sheet
β-strand	11-13	3	1
β-strand	16-17	2	2
β-strand	33	1	3
β-strand	43	1	4
β-strand	46	1	4
α-helix	56-58	3
β-strand	82	1	5
β-strand	83	1	3
β-strand	90	1	6
α-helix	96-104	9
β-strand	106	1	7
β-strand	113	1	7
α-helix	117-125	9
α-helix	134-144	11
α-helix	147-150	4
β-strand	153	1	8
β-strand	160	1	8
β-strand	163-166	4	9
β-strand	178-181	4	9
α-helix	191-200	10
α-helix	208-214	7
β-strand	221	1	9
α-helix	224-228	5
α-helix	240-242	3
β-strand	258	1	6
β-strand	263	1	5
α-helix	264-265	2
α-helix	284-305	22
α-helix	309-324	16
α-helix	349-351	3
β-strand	371-373	3	10
β-strand	376-377	2	11
β-strand	380	1	12
β-strand	381	1	13
β-strand	391-393	3	14
α-helix	396-399	4
β-strand	403-407	5	15
α-helix	413-422	10
β-strand	430-434	5	15
β-strand	442-443	2	15
β-strand	461-465	5	15
β-strand	471-472	2	14
β-strand	473-474	2	11
β-strand	487	1	16
β-strand	488-491	4	14
β-strand	498	1	13
β-strand	499	1	14
α-helix	505-508	4
β-strand	516	1	12
β-strand	519-520	2	11
α-helix	525-534	10
β-strand	536	1	16
β-strand	542	1	17
β-strand	549	1	17
α-helix	555-564	10
α-helix	570	1
β-strand	571	1	18
α-helix	572	1
α-helix	573-581	9
α-helix	592-595	4
β-strand	597	1	19
β-strand	603	1	19
β-strand	604	1	18
α-helix	606-614	9
β-strand	625-629	5	20
β-strand	651-655	5	20
β-strand	659-661	3	20
α-helix	677-708	32
α-helix	718-720	3
α-helix	721-746	26
α-helix	761-784	24
α-helix	785-786	2
α-helix	790-797	8
α-helix	803-806	4
α-helix	807-811	5
β-strand	818	1	21
β-strand	821	1	21
α-helix	858-888	31
β-strand	897-898	2	22
β-strand	904-905	2	22
β-strand	913	1	22
α-helix	916-918	3
β-strand	921	1	23
α-helix	935-941	7
α-helix	956-967	12
α-helix	975-977	3
α-helix	992-994	3
α-helix	999-1026	28
α-helix	1052-1059	8
α-helix	1065-1080	16
β-strand	1082	1	23
α-helix	1083-1084	2
α-helix	1089-1097	9
α-helix	1123-1130	8
β-strand	1141-1145	5	24
α-helix	1153-1160	8
α-helix	1166-1170	5
β-strand	1173-1175	3	25
β-strand	1184-1186	3	25
α-helix	1190-1193	4
α-helix	1203-1209	7
β-strand	1224-1225	2	26
β-strand	1229-1230	2	26
β-strand	1232	1	25
α-helix	1257-1264	8
α-helix	1267-1269	3
β-strand	1281-1282	2	27
β-strand	1285	1	28
β-strand	1291	1	28
β-strand	1292-1293	2	24
β-strand	1294-1295	2	27
α-helix	1302-1305	4
β-strand	1309-1316	8	24
α-helix	1321-1344	24
α-helix	1352-1360	9
α-helix	1383-1387	5
α-helix	1395-1401	7
β-strand	1405-1406	2	2
α-helix	1414-1417	4
α-helix	1424-1427	4
β-strand	1428	1	29
β-strand	1431-1432	2	30
α-helix	1451-1454	4

Chain B: 36 helices, 74 β-strands

Element	Residues	Length	Sheet
α-helix	47-54	8
α-helix	62-67	6
α-helix	68-72	5
α-helix	73-75	3
β-strand	95-100	6	31
α-helix	115-120	6
β-strand	126	1	32
β-strand	129-133	5	31
β-strand	153	1	32
α-helix	170-174	5
β-strand	184-186	3	33
β-strand	191-193	3	33
β-strand	196-197	2	34
β-strand	198-199	2	35
β-strand	205	1	36
β-strand	219	1	36
β-strand	232	1	37
β-strand	236	1	38
β-strand	239	1	38
β-strand	242	1	37
β-strand	251	1	37
α-helix	253-259	7
α-helix	267-270	4
α-helix	277-280	4
α-helix	289-292	4
α-helix	300-306	7
α-helix	323-330	8
α-helix	344-358	15
α-helix	372-374	3
β-strand	376-377	2	35
α-helix	380-406	27
α-helix	416-419	4
α-helix	429-438	10
β-strand	441	1	39
β-strand	452	1	39
β-strand	457	1	33
α-helix	463-468	6
β-strand	472	1	40
β-strand	473-474	2	34
α-helix	489-490	2
β-strand	497	1	41
β-strand	513	1	40
β-strand	514	1	41
β-strand	520	1	42
α-helix	527-535	9
α-helix	547-550	4
α-helix	553	1
β-strand	554-556	3	43
β-strand	561-564	4	43
α-helix	568-581	14
β-strand	589-593	5	43
β-strand	598-602	5	43
β-strand	608	1	42
β-strand	613-614	2	44
α-helix	626-632	7
α-helix	640-643	4
β-strand	646	1	44
β-strand	650	1	42
β-strand	659-660	2	44
α-helix	663-665	3
β-strand	672-673	2	44
α-helix	677-679	3
α-helix	691-693	3
β-strand	694	1	45
α-helix	696-705	10
β-strand	709	1	46
β-strand	711	1	47
β-strand	725-728	4	47
β-strand	736	1	48
β-strand	753-758	6	49
β-strand	770-771	2	50
β-strand	772	1	51
β-strand	773-774	2	50
β-strand	785-790	6	47
β-strand	829	1	52
β-strand	835-836	2	47
β-strand	841-843	3	52
β-strand	871-872	2	52
β-strand	879-888	10	47
β-strand	894-902	9	47
β-strand	911	1	50
β-strand	912-914	3	49
β-strand	921-926	6	50
β-strand	933	1	53
β-strand	942	1	49
β-strand	943	1	51
β-strand	954	1	45
α-helix	956-970	15
α-helix	973	1
β-strand	974	1	48
α-helix	985-994	10
β-strand	1001-1002	2	54
β-strand	1005	1	53
β-strand	1012	1	53
β-strand	1015	1	55
β-strand	1017-1018	2	54
β-strand	1019-1026	8	49
β-strand	1027	1	46
α-helix	1031-1033	3
β-strand	1043	1	56
β-strand	1060-1062	3	10
α-helix	1067-1073	7
α-helix	1077-1084	8
β-strand	1090	1	57
β-strand	1093-1094	2	58
β-strand	1117-1118	2	58
β-strand	1121	1	57
α-helix	1123-1133	11
β-strand	1140	1	2
β-strand	1143-1145	3	1

Chain C: 11 helices, 23 β-strands

Element	Residues	Length	Sheet
β-strand	4	1	59
β-strand	6-7	2	60
β-strand	11	1	55
β-strand	12-13	2	60
α-helix	33-38	6
β-strand	44-47	4	61
β-strand	52-54	3	61
α-helix	61-72	12
β-strand	77-86	10	62
α-helix	94-103	10
β-strand	106-107	2	63
β-strand	134-139	6	62
β-strand	142	1	64
β-strand	157	1	64
β-strand	161	1	65
α-helix	164-166	3
α-helix	173-176	4
α-helix	177-180	4
β-strand	185-186	2	63
β-strand	195	1	65
β-strand	201-211	11	62
β-strand	222	1	66
α-helix	229-230	2
β-strand	231-233	3	67
α-helix	243-250	8
β-strand	256-258	3	68
β-strand	265-267	3	68
α-helix	278-280	3
β-strand	291-293	3	67
β-strand	294	1	59
β-strand	302	1	61
β-strand	304	1	66
α-helix	310-329	20
α-helix	331-333	3

Chain D: 8 helices, 1 β-strand

Element	Residues	Length	Sheet
β-strand	3	1	69
α-helix	15-24	10
α-helix	34-37	4
α-helix	41-47	7
α-helix	60-67	8
α-helix	100-109	10
α-helix	118-125	8
α-helix	132-137	6
α-helix	149-152	4

Chain E: 10 helices, 10 β-strands

Element	Residues	Length	Sheet
α-helix	3-26	24
β-strand	28	1	70
α-helix	32-35	4
α-helix	41	1
α-helix	42-46	5
β-strand	47	1	71
β-strand	53	1	71
β-strand	64	1	70
α-helix	66-69	4
β-strand	80-82	3	72
α-helix	90-103	14
β-strand	108-112	5	72
α-helix	121-123	3
β-strand	132-136	5	72
β-strand	153-155	3	73
α-helix	158-168	11
α-helix	176-177	2
α-helix	185-188	4
β-strand	196-202	7	73
β-strand	206-212	7	73

Chain F: 3 helices, 3 β-strands

Element	Residues	Length	Sheet
α-helix	87-102	16
α-helix	105-107	3
α-helix	117-127	11
β-strand	133-135	3	30
β-strand	136	1	29
β-strand	145-147	3	30

Chain G: 5 helices, 13 β-strands

Element	Residues	Length	Sheet
β-strand	5-13	9	69
α-helix	14	1
α-helix	15-17	3
α-helix	22-31	10
β-strand	39	1	74
β-strand	43	1	74
β-strand	45-48	4	69
β-strand	52	1	69
β-strand	57-58	2	30
β-strand	59	1	69
β-strand	66-76	11	69
β-strand	84-88	5	75
β-strand	100	1	75
β-strand	128-129	2	76
β-strand	139-140	2	76
β-strand	145-149	5	75
α-helix	163-173	11
α-helix	174-176	3

Chain H: 1 helix, 13 β-strands

Element	Residues	Length	Sheet
β-strand	4	1	77
β-strand	8-16	9	77
β-strand	23-30	8	77
β-strand	38-43	6	77
β-strand	55-60	6	77
α-helix	80-83	4
β-strand	95-96	2	77
β-strand	99	1	78
β-strand	100	1	77
β-strand	104-106	3	77
β-strand	112-117	6	77
β-strand	122-127	6	77
β-strand	140	1	78
β-strand	141-145	5	77

12 more chain groups are not listed. Open the entry in the viewer and use the sequence panel to see them.

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
DNA-directed RNA polymerase III subunit RPC1	A	protein	1460	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P04051 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC2	B	protein	1149	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P22276 (AlphaFold model)
DNA-directed RNA polymerases I and III subunit RPAC1	C	protein	335	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P07703 (AlphaFold model)
DNA-directed RNA polymerase III subunit RPC9	D	protein	161	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P47076 (AlphaFold model)
DNA-directed RNA polymerases I, II, and III subunit RPABC1	E	protein	215	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P20434
DNA-directed RNA polymerases I, II, and III subunit RPABC2	F	protein	155	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P20435
DNA-directed RNA polymerase III subunit RPC8	G	protein	212	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P35718
DNA-directed RNA polymerases I, II, and III subunit RPABC3	H	protein	146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P20436
DNA-directed RNA polymerase III subunit RPC10	I	protein	110	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	Q04307
DNA-directed RNA polymerases I, II, and III subunit RPABC5	J	protein	70	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P22139
DNA-directed RNA polymerases I and III subunit RPAC2	K	protein	142	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P28000
DNA-directed RNA polymerases I, II, and III subunit RPABC4	L	protein	70	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	P40422

10 more molecules are not listed.

Sequence of entity 1 (A), FASTA

>6EU0_1 DNA-directed RNA polymerase III subunit RPC1 (chains A)
MKEVVVSETPKRIKGLEFSALSAADIVAQSEVEVSTRDLFDLEKDRAPKANGALDPKMGV
SSSSLECATCHGNLASCHGHFGHLKLALPVFHIGYFKATIQILQGICKNCSAILLSETDK
RQFLHELRRPGVDNLRRMGILKKILDQCKKQRRCLHCGALNGVVKKAAAGAGSAALKIIH
DTFRWVGKKSAPEKDIWVGEWKEVLAHNPELERYVKRCMDDLNPLKTLNLFKQIKSADCE
LLGIDATVPSGRPETYIWRYLPAPPVCIRPSVMMQDSPASNEDDLTVKLTEIVWTSSLIK
AGLDKGISINNMMEHWDYLQLTVAMYINSDSVNPAMLPGSSNGGGKVKPIRGFCQRLKGK
QGRFRGNLSGKRVDFSGRTVISPDPNLSIDEVAVPDRVAKVLTYPEKVTRYNRHKLQELI
VNGPNVHPGANYLLKRNEDARRNLRYGDRMKLAKNLQIGDVVERHLEDGDVVLFNRQPSL
HRLSILSHYAKIRPWRTFRLNECVCTPYNADFDGDEMNLHVPQTEEARAEAINLMGVKNN
LLTPKSGEPIIAATQDFITGSYLISHKDSFYDRATLTQLLSMMSDGIEHFDIPPPAIMKP
YYLWTGKQVFSLLIKPNHNSPVVINLDAKNKVFVPPKSKSLPNEMSQNDGFVIIRGSQIL
SGVMDKSVLGDGKKHSVFYTILRDYGPQEAANAMNRMAKLCARFLGNRGFSIGINDVTPA
DDLKQKKEELVEIAYHKCDELITLFNKGELETQPGCNEEQTLEAKIGGLLSKVREEVGDV
CINELDNWNAPLIMATCGSKGSTLNVSQMVAVVGQQIISGNRVPDGFQDRSLPHFPKNSK
TPQSKGFVRNSFFSGLSPPEFLFHAISGREGLVDTAVKTAETGYMSRRLMKSLEDLSCQY
DNTVRTSANGIVQFTYGGDGLDPLEMEGNAQPVNFNRSWDHAYNITFNNQDKGLLPYAIM
ETANEILGPLEERLVRYDNSGCLVKREDLNKAEYVDQYDAERDFYHSLREYINGKATALA
NLRKSRGMLGLLEPPAKELQGIDPDETVPDNVKTSVSQLYRISEKSVRKFLEIALFKYRK
ARLEPGTAIGAIGAQSIGEPGTQMTLKTFHFAGVASMNVTLGVPRIKEIINASKVISTPI
INAVLVNDNDERAARVVKGRVEKTLLSDVAFYVQDVYKDNLSFIQVRIDLGTIDKLQLEL
TIEDIAVAITRASKLKIQASDVNIIGKDRIAINVFPEGYKAKSISTSAKEPSENDVFYRM
QQLRRALPDVVVKGLPDISRAVINIRDDGKRELLVEGYGLRDVMCTDGVIGSRTTTNHVL
EVFSVLGIEAARYSIIREINYTMSNHGMSVDPRHIQLLGDVMTYKGEVLGITRFGLSKMR
DSVLQLASFEKTTDHLFDAAFYMKKDAVEGVSECIILGQTMSIGTGSFKVVKGTNISEKD
LVPKRCLFESLSNEAALKAN

Sequence of entity 2 (B), FASTA

>6EU0_2 DNA-directed RNA polymerase III subunit RPC2 (chains B)
MVAATKRRKTHIHKHVKDEAFDDLLKPVYKGKKLTDEINTAQDKWHLLPAFLKVKGLVKQ
HLDSFNYFVDTDLKKIIKANQLILSDVDPEFYLKYVDIRVGKKSSSSTKDYLTPPHECRL
RDMTYSAPIYVDIEYTRGRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLD
PGGYFIVNGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKNGKI
YLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNLEESSKLDIYTQQQ
ALEYIGAKVKTMRRQKLTILQEGIEAIATTVIAHLTVEALDFREKALYIAMMTRRVVMAM
YNPKMIDDRDYVGNKRLELAGQLISLLFEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALL
SINVHSNNITSGLNRAISTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKS
RKVSGPRALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLGVED
ITLIDSASLHLNYGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEFISIYSNSHQMAVH
IATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDFDDFLKLGLVEYLDVNEENDSYIA
LYEKDIVPSMTHLEIEPFTILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKR
IDTLLYLMTYPQQPMVKTKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDR
GFGRCETRRKTTTVLKRYANHTQDIIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQSGQ
IYINKSVPTNSADAPNPNNVNVQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKVLL
RQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHGFPSRMTVGKMIE
LISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNYSGKDMLYSGITGECLQAYIFFG
PIYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLL
ERLMISSDAFEVDVCDKCGLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPR
LRLEDIFQQ

Sequence of entity 3 (C), FASTA

>6EU0_3 DNA-directed RNA polymerases I and III subunit RPAC1 (chains C)
MSNIVGIEYNRVTNTTSTDFPGFSKDAENEWNVEKFKKDFEVNISSLDAREANFDLINID
TSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRIGLVPLKVDPDMLTWVDSNL
PDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELYNNAHVYARDLKFEPQGRQSTTFA
DCPVVPADPDILLAKLRPGQEISLKAHCILGIGGDHAKFSPVSTASYRLLPQINILQPIK
GESARRFQKCFPPGVIGIDEGSDEAYVKDARKDTVSREVLRYEEFADKVKLGRVRNHFIF
NVESAGAMTPEEIFFKSVRILKNKAEYLKNCPITQ

Sequence of entity 4 (D), FASTA

>6EU0_4 DNA-directed RNA polymerase III subunit RPC9 (chains D)
MKVLEERNAFLSDYEVLKFLTDLEKKHLWDQKSLAALKKSRSKGKQNRPYNHPELQGITR
NVVNYLSINKNFINQEDEGEERESSGAKDAEKSGISKMSDESFAELMTKLNSFKLFKAEK
LQIVNQLPANMVHLYSIVEECDARFDEKTIEEMLEIISGYA

Sequence of entity 5 (E), FASTA

>6EU0_5 DNA-directed RNA polymerases I, II, and III subunit RPABC1 (chains E)
MDQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSF
QANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSA
MKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQR
ADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM

Sequence of entity 6 (F), FASTA

>6EU0_6 DNA-directed RNA polymerases I, II, and III subunit RPABC2 (chains F)
MSDYEEAFNDGNENFEDFDVEHFSDEETYEEKPQFKDGETTDANGKTIVTGGNGPEDFQQ
HEQIRRKTLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRI
AMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL

Sequence of entity 7 (G), FASTA

>6EU0_7 DNA-directed RNA polymerase III subunit RPC8 (chains G)
MFILSKIADLVRIPPDQFHRDTISAITHQLNNKFANKIIPNVGLCITIYDLLTVEEGQLK
PGDGSSYINVTFRAVVFKPFLGEIVTGWISKCTAEGIKVSLLGIFDDIFIPQNMLFEGCY
YTPEESAWIWPMDEETKLYFDVNEKIRFRIEREVFVDVKPKSPKERELEERAQLENEIEG
KNEETPQNEKPPAYALLGSCQTDGMGLVSWWE

Sequence of entity 8 (H), FASTA

>6EU0_8 DNA-directed RNA polymerases I, II, and III subunit RPABC3 (chains H)
MSNTLFDDIFQVSEVDPGRYNKVCRIEAASTTQDQCKLTLDINVELFPVAAQDSLTVTIA
SSLNLEDTPANDSSATRSWRPPQAGDRSLADDYDYVMYGTAYKFEEVSKDLIAVYYSFGG
LLMRLEGNYRNLNNLKQENAYLLIRR

Sequence of entity 9 (I), FASTA

>6EU0_9 DNA-directed RNA polymerase III subunit RPC10 (chains I)
MLSFCPSCNNMLLITSGDSGVYTLACRSCPYEFPIEGIEIYDRKKLPRKEVDDVLGGGWD
NVDQTKTQCPNYDTCGGESAYFFQLQIRSADEPMTTFYKCVNCGHRWKEN

Sequence of entity 10 (J), FASTA

>6EU0_10 DNA-directed RNA polymerases I, II, and III subunit RPABC5 (chains J)
MIVPVRCFSCGKVVGDKWESYLNLLQEDELDEGTALSRLGLKRYCCRRMILTHVDLIEKF
LRYNPLEKRD

Sequence of entity 11 (K), FASTA

>6EU0_11 DNA-directed RNA polymerases I and III subunit RPAC2 (chains K)
MTEDIEQKKTATEVTPQEPKHIQEEEEQDVDMTGDEEQEEEPDREKIKLLTQATSEDGTS
ASFQIVEEDHTLGNALRYVIMKNPDVEFCGYSIPHPSENLLNIRIQTYGETTAVDALQKG
LKDLMDLCDVVESKFTEKIKSM

Sequence of entity 12 (L), FASTA

>6EU0_12 DNA-directed RNA polymerases I, II, and III subunit RPABC4 (chains L)
MSREGFQIPTNLDAAAAGTSQARTATLKYICAECSSKLSLSRTDAVRCKDCGHRILLKAR
TKRLVQFEAR

Ligands and cofactors

ID	Name	Formula	Copies
ZN	Zinc ion	Zn	7
MG	Magnesium ion	Mg	1

Primary citation

Structural basis of RNA polymerase III transcription initiation. Abascal-Palacios, G., Ramsay, E.P., Beuron, F. et al. Nature (2018) 553:301-306. DOI 10.1038/nature25441 · PubMed

Other PDB entries of the same protein (UniProt P04051 (AlphaFold model), which also has an AlphaFold model), best resolution first:

7Z0H 2.6 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.6 A (focus subunit AC40).
7Z1O 2.7 Å, Structure of yeast RNA Polymerase III PTC + NTPs
7Z31 2.76 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.7 A (focus subunit C11,…
7Z1L 2.8 Å, Structure of yeast RNA Polymerase III Pre-Termination Complex (PTC)
7Z30 2.9 Å, Structure of yeast RNA Polymerase III-Ty1 integrase complex at 2.9 A (focus subunit C11…
7Z2Z 3.07 Å, Structure of yeast RNA Polymerase III-DNA-Ty1 integrase complex (Pol III-DNA-IN1) at 3.1 A
8BWS 3.2 Å, Structure of yeast RNA Polymerase III elongation complex at 3.3 A
6TUT 3.25 Å, Cryo-EM structure of the RNA Polymerase III-Maf1 complex
6EU3 3.3 Å, Apo RNA Polymerase III - closed conformation (cPOL3)
6EU1 3.4 Å, RNA Polymerase III - open DNA complex (OC-POL3).
6EU2 3.4 Å, Apo RNA Polymerase III - open conformation (oPOL3)
7Z1M 3.4 Å, Structure of yeast RNA Polymerase III Elongation Complex (EC)

Browse structure collections

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