AP-1 complex subunit mu-1 (Ap1m1) is a 423-residue protein from Mus musculus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P35585.
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The mean pLDDT of this model is 89.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 71% |
| 70 to 90 | Confident: backbone generally right | 20% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 1% |
What pLDDT means and how to read it
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes (PubMed:36261523). The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (PubMed:36261523)
Adaptor protein complex 1 (AP-1) is a heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta-type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or AP1S2 or AP1S3) (PubMed:36261523). Interacts with MARCHF11 (By similarity)
Golgi apparatus, Cytoplasmic vesicle, clathrin-coated vesicle membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7R4H | EM | 2.34 Å | M=1-423 |
| 4EN2 | X-ray | 2.58 Å | A/M=158-423 |
| 4EMZ | X-ray | 2.9 Å | A/M=158-423 |
| 4P6Z | X-ray | 3.0 Å | M=1-423 |
| 6CM9 | EM | 3.73 Å | M=1-423 |
| 6DFF | EM | 3.9 Å | M=1-423 |
| 1W63 | X-ray | 4.0 Å | M/N/O/P/R/V=1-423 |
| 6D83 | EM | 4.27 Å | M=1-423 |
| 6D84 | EM | 6.72 Å | M/P=1-423 |
| 6CRI | EM | 6.8 Å | M/W/X=2-423 |
| 4HMY | X-ray | 7.0 Å | M=1-423 |
| 8D4E | EM | 9.2 Å | M=2-423 |
| 8D4C | EM | 9.3 Å | J/M=1-423 |
| 8D9W | EM | 9.3 Å | M/X/Z/a=1-423 |
| 8D9V | EM | 9.4 Å | J/M=1-423 |
| 7UX3 | EM | 9.6 Å | M=2-423 |
| 8D4D | EM | 9.6 Å | J/M=1-423 |
| 8D4F | EM | 9.8 Å | J/M=1-423 |
| 8D4G | EM | 11.6 Å | J/M=1-423 |
| 8D9R | EM | 20.0 Å | M/j/k/l/m/n=1-423 |
Showing 20 of 23 experimental structures (best resolution first).
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