P38742: Nitrogen permease regulator 3 (NPR3)

Nitrogen permease regulator 3 (NPR3) is a 1146-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P38742.

Gene
NPR3
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
1146 residues
Mean pLDDT
61.1
Model
AF-P38742-F1 v6
Model created
1 Aug 2025
PDB structures
4

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Model confidence (pLDDT)

The mean pLDDT of this model is 61.1 (low overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate23%
70 to 90Confident: backbone generally right23%
50 to 70Low: treat with caution5%
Below 50Very low: often disordered regions49%

What pLDDT means and how to read it

Function

Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis. Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division

Subunit structure

Component of the SEA complex composed of at least IML1/SEA1, RTC1/SEA2, MTC5/SEA3, NPR2, NPR3, SEA4, SEC13 and SEH1. Forms a heterodimer with NPR2

Subcellular location

Vacuole membrane

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8AE6EM2.7 ÅU=1-1146
8ADLEM2.95 ÅU/V=1-1146
9H4QEM3.1 Åh=1-1146
9H5KEM3.2 Åh/i=1-1146

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