Protein disulfide-isomerase is a 505-residue protein from Humicola insolens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P55059.
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The mean pLDDT of this model is 89.7 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 86% |
| 70 to 90 | Confident: backbone generally right | 3% |
| 50 to 70 | Low: treat with caution | 0% |
| Below 50 | Very low: often disordered regions | 10% |
What pLDDT means and how to read it
Participates in the folding of proteins containing disulfide bonds, may be involved in glycosylation, prolyl hydroxylation and triglyceride transfer
Endoplasmic reticulum lumen
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5CRW | X-ray | 1.6 Å | A=228-469 |
| 3WT1 | X-ray | 1.85 Å | A/B/C/D=228-469 |
| 3WT2 | X-ray | 3.3 Å | A/B/C=228-469 |
| 2DJJ | NMR | A=354-469 | |
| 2DJK | NMR | A=227-355 | |
| 2KP1 | NMR | A=354-469 | |
| 2KP2 | NMR | A=228-355 | |
| 2RUE | NMR | A=354-469 | |
| 2RUF | NMR | A=354-469 |
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