Kinesin heavy chain isoform 5C (Kif5c) is a 955-residue protein from Rattus norvegicus. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P56536.
Explore in 3D Color by confidence AlphaFold DB UniProt
The mean pLDDT of this model is 79.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 30% |
| 70 to 90 | Confident: backbone generally right | 52% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 11% |
What pLDDT means and how to read it
Microtubule-associated force-producing protein that may play a role in organelle transport (By similarity). Has ATPase activity (PubMed:27452403). Involved in synaptic transmission (By similarity). Mediates dendritic trafficking of mRNAs (By similarity). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (PubMed:23576431)
Oligomer composed of two heavy chains and two light chains. Interacts with GRIP1. Interacts with TRAK1. Interacts with ZFYVE27 (By similarity). Interacts with KLC3 (PubMed:11319135)
Cytoplasm, cytoskeleton, Cell projection, dendrite
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2KIN | X-ray | 2.0 Å | A=2-239 |
| 5HLE | X-ray | 2.9 Å | A=10-320 |
| 3KIN | X-ray | 3.1 Å | A/C=2-239 |
| 5HNZ | EM | 5.8 Å | K=10-325 |
| 5HNY | EM | 6.3 Å | K=10-325 |
| 5HNW | EM | 6.6 Å | K=10-320 |
| 5HNX | EM | 6.6 Å | K=10-320 |
| 8TT7 | NMR | A/B=325-376 |
MolViewer loads the AlphaFold model straight from AlphaFold DB into your browser. Show it as a cartoon, color by pLDDT, measure distances and angles, and load a PDB structure next to it to compare.