Cyclin-dependent kinases regulatory subunit 1 (CKS1B) is a 79-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P61024.
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The mean pLDDT of this model is 92.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 86% |
| 70 to 90 | Confident: backbone generally right | 6% |
| 50 to 70 | Low: treat with caution | 5% |
| Below 50 | Very low: often disordered regions | 3% |
What pLDDT means and how to read it
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function
Forms a homohexamer that can probably bind six kinase subunits
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2AST | X-ray | 2.3 Å | C=5-73 |
| 1BUH | X-ray | 2.6 Å | B=1-79 |
| 4YC6 | X-ray | 2.6 Å | B/D/F/H=1-79 |
| 1DKT | X-ray | 2.9 Å | A/B=1-79 |
| 9QO4 | EM | 2.95 Å | N=1-79 |
| 2ASS | X-ray | 3.0 Å | C=5-73 |
| 8OR0 | EM | 3.1 Å | G=1-73 |
| 1DKS | X-ray | 3.2 Å | A/B=1-79 |
| 9QO0 | EM | 3.26 Å | N=1-79 |
| 8BYA | EM | 3.38 Å | F=1-79 |
| 8BYL | EM | 3.5 Å | C=1-79 |
| 7NJ0 | EM | 3.6 Å | D=1-79 |
| 7B5L | EM | 3.8 Å | K=1-73 |
| 7B5R | EM | 3.8 Å | K=1-79 |
| 8OR4 | EM | 3.8 Å | G=5-73 |
| 9QO2 | EM | 3.8 Å | N=1-79 |
| 7B5M | EM | 3.91 Å | K=1-79 |
| 9QO5 | EM | 4.0 Å | N=1-79 |
| 9QO3 | EM | 4.6 Å | N=1-79 |
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