P62424: Large ribosomal subunit protein eL8 (RPL7A)

Large ribosomal subunit protein eL8 (RPL7A) is a 266-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P62424.

Gene
RPL7A
Organism
Homo sapiens
Length
266 residues
Mean pLDDT
90.6
Model
AF-P62424-F1 v6
Model created
1 Aug 2025
PDB structures
173

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Model confidence (pLDDT)

The mean pLDDT of this model is 90.6 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.

pLDDT bandMeaningShare of residues
Above 90Very high: backbone and side chains are usually accurate81%
70 to 90Confident: backbone generally right10%
50 to 70Low: treat with caution7%
Below 50Very low: often disordered regions2%

What pLDDT means and how to read it

Function

Component of the large ribosomal subunit (PubMed:23636399, PubMed:32669547). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:32669547)

Subunit structure

Component of the large ribosomal subunit (PubMed:23636399, PubMed:32669547). Interacts with CRY1 (By similarity). Interacts with DICER1, AGO2, TARBP2, MOV10 and EIF6; they form a large RNA-induced silencing complex (RISC) (PubMed:17507929)

Subcellular location

Cytoplasm

Experimental structures in the PDB

Compare the prediction with experimentally determined structures of the same protein:

PDB IDMethodResolutionChains and residues
8A3DEM1.67 Ån=1-266
8GLPEM1.67 ÅLG=1-266
8QYXEM1.78 ÅB1=1-266
8QOIEM1.9 ÅLG=1-266
9O3WEM1.9 ÅLG=1-266
8YOOEM2.0 ÅLG=1-266
9C3HEM2.0 ÅLG=1-266
9I2DEM2.19 ÅLG=1-266
9PBEEM2.19 ÅLG=26-266
7OW7EM2.2 Ån=1-266
8QFDEM2.2 ÅG=1-266
8YOPEM2.2 ÅLG=1-266
9GULEM2.2 ÅLG=1-266
9O3YEM2.2 ÅLG=1-266
8JDKEM2.26 ÅM=1-266
8G5YEM2.29 ÅLG=1-266
9S3DEM2.32 ÅLG=1-266
9RPVEM2.35 ÅLG/MG=1-266
9S3BEM2.38 ÅLG=1-266
8K2CEM2.4 ÅLG=1-266

Showing 20 of 173 experimental structures (best resolution first).

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