Fibrinogen-binding protein (fib) is a 165-residue protein from Staphylococcus aureus (strain Mu50 / ATCC 700699). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P68799.
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The mean pLDDT of this model is 80.6 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 46% |
| 70 to 90 | Confident: backbone generally right | 29% |
| 50 to 70 | Low: treat with caution | 9% |
| Below 50 | Very low: often disordered regions | 16% |
What pLDDT means and how to read it
Extracellular fibrinogen-binding protein that plays an important role in virulence. By interacting with the alpha chain of fibrinogen and its derivative fibrin, enhances a non-functional interaction between fibrinogen and platelets and is responsible for repression of fibrinogen-dependent platelet aggregation. In addition, assembles a fibrinogen protective shield around the bacteria which results in impaired phagocytic clearance by the host. Mechanistically, interacts with host complement C3b deposited on the surface of the bacterium via its C-terminal and then recruits fibrinogen via its N-terminal
Interacts with host fibrinogen alpha chain/FGA. Interacts with host complement protein C3
Secreted
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2GOM | X-ray | 1.25 Å | A/B=105-165 |
| 2GOX | X-ray | 2.2 Å | B/D=101-165 |
| 9N20 | X-ray | 3.3 Å | C=94-165 |
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