P69905: Hemoglobin subunit alpha

Hemoglobin subunit alpha (HBA1) is a 142-residue protein from Homo sapiens. UniProt accession: P69905.

Function

Involved in oxygen transport from the lung to the various peripheral tissues

Disease associations

Heinz body anemias (HEIBAN); Alpha-thalassemia (A-THAL); Hemoglobin H disease (HBH)

Subunit structure

Heterotetramer of two alpha chains and two beta chains in adult hemoglobin A (HbA); two alpha chains and two delta chains in adult hemoglobin A2 (HbA2); two alpha chains and two epsilon chains in early embryonic hemoglobin Gower-2; two alpha chains and two gamma chains in fetal hemoglobin F (HbF)

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Source: AlphaFold · UniProt P69905