Hemoglobin subunit alpha (HBA1) is a 142-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: P69905.
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The mean pLDDT of this model is 98.1 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 99% |
| 70 to 90 | Confident: backbone generally right | 0% |
| 50 to 70 | Low: treat with caution | 1% |
| Below 50 | Very low: often disordered regions | 0% |
What pLDDT means and how to read it
Involved in oxygen transport from the lung to the various peripheral tissues
Heterotetramer of two alpha chains and two beta chains in adult hemoglobin A (HbA); two alpha chains and two delta chains in adult hemoglobin A2 (HbA2); two alpha chains and two epsilon chains in early embryonic hemoglobin Gower-2; two alpha chains and two gamma chains in fetal hemoglobin F (HbF)
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2W72 | X-ray | 1.07 Å | A/C=2-142 |
| 1IRD | X-ray | 1.25 Å | A=2-142 |
| 2DN1 | X-ray | 1.25 Å | A=2-142 |
| 2DN2 | X-ray | 1.25 Å | A/C=2-142 |
| 2DN3 | X-ray | 1.25 Å | A=2-142 |
| 7DY4 | X-ray | 1.3 Å | A/C/E/G=2-142 |
| 3S66 | X-ray | 1.4 Å | A=2-142 |
| 6KA9 | X-ray | 1.4 Å | A/C/E/G=2-142 |
| 6KAO | X-ray | 1.4 Å | A=2-142 |
| 6LCW | X-ray | 1.4 Å | A/C/E/G=2-142 |
| 6LCX | X-ray | 1.4 Å | A/C/E/G=2-142 |
| 7DY3 | X-ray | 1.4 Å | A/C/E/G=2-142 |
| 1J40 | X-ray | 1.45 Å | A/C/E/G=2-142 |
| 1J41 | X-ray | 1.45 Å | A/C/E/G=2-142 |
| 2D5Z | X-ray | 1.45 Å | A/C=2-142 |
| 6KAE | X-ray | 1.45 Å | A/C/E/G=2-142 |
| 6KAH | X-ray | 1.45 Å | A/C/E/G=2-142 |
| 6KAI | X-ray | 1.45 Å | A/C/E/G=2-142 |
| 6KAP | X-ray | 1.45 Å | A=2-142 |
| 6L5V | X-ray | 1.45 Å | A=2-142 |
Showing 20 of 355 experimental structures (best resolution first).
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