Cytoplasmic 60S subunit biogenesis factor REH1 (REH1) is a 432-residue protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c). This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q06709.
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The mean pLDDT of this model is 70.9 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 35% |
| 70 to 90 | Confident: backbone generally right | 25% |
| 50 to 70 | Low: treat with caution | 6% |
| Below 50 | Very low: often disordered regions | 34% |
What pLDDT means and how to read it
Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit. May act redundantly with REI1 to directly promote a stabilizing structural rearrangement in cytoplasmic 60S subunit maturation independent on the REI1-specific ARX1 recycling
Associates with nascent pre-60S particles that have not yet entered the translating pool, and is released from mature 60S subunits. Interacts with pre-60S factors NMD3, LSG1, and TIF6
Cytoplasm
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 5H4P | EM | 3.07 Å | z=377-432 |
| 6QIK | EM | 3.1 Å | z=1-432 |
| 8UTI | EM | 3.13 Å | z=2-432 |
| 8UT0 | EM | 3.22 Å | z=2-432 |
| 6RI5 | EM | 3.3 Å | z=1-432 |
| 6QT0 | EM | 3.4 Å | z=1-432 |
| 6QTZ | EM | 3.5 Å | z=1-432 |
| 6S05 | EM | 3.9 Å | z=1-432 |
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