AP-1 complex subunit beta-1 (AP1B1) is a 949-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q10567.
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The mean pLDDT of this model is 81.3 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 56% |
| 70 to 90 | Confident: backbone generally right | 27% |
| 50 to 70 | Low: treat with caution | 4% |
| Below 50 | Very low: often disordered regions | 13% |
What pLDDT means and how to read it
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes (PubMed:31630791, PubMed:36261523). The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules (PubMed:36261523)
Adaptor protein complex 1 (AP-1) is a heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta-type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or AP1S2 or AP1S3)
Golgi apparatus, Cytoplasmic vesicle, clathrin-coated vesicle membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 7R4H | EM | 2.34 Å | B=1-584 |
| 4P6Z | X-ray | 3.0 Å | B=1-584 |
| 6CM9 | EM | 3.73 Å | B=1-584 |
| 6DFF | EM | 3.9 Å | B=1-584 |
| 6D83 | EM | 4.27 Å | B=1-584 |
| 6D84 | EM | 6.72 Å | B/F=1-584 |
| 6CRI | EM | 6.8 Å | B/I/J=14-583 |
| 4HMY | X-ray | 7.0 Å | B=1-584 |
| 8D4E | EM | 9.2 Å | B=1-949 |
| 8D4C | EM | 9.3 Å | A/B=2-949 |
| 8D9W | EM | 9.3 Å | A/B/D/E=1-949 |
| 8D9V | EM | 9.4 Å | A/B=1-949 |
| 7UX3 | EM | 9.6 Å | B=2-949 |
| 8D4D | EM | 9.6 Å | A/B=1-949 |
| 8D4F | EM | 9.8 Å | A/B=1-949 |
| 8D4G | EM | 11.6 Å | A/B=1-949 |
| 8D9R | EM | 20.0 Å | A/B/D/E/F/I=1-949 |
| 8D9S | EM | 20.0 Å | A/B/D/E/F/I=1-949 |
| 8D9T | EM | 20.0 Å | A/B/D/E/F/I=1-949 |
| 8D9U | EM | 20.0 Å | A/B/D/E/F/I=1-949 |
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