Sarcolemmal membrane-associated protein (SLMAP) is a 828-residue protein from Homo sapiens. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q14BN4.
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The mean pLDDT of this model is 77.2 (confident overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 41% |
| 70 to 90 | Confident: backbone generally right | 34% |
| 50 to 70 | Low: treat with caution | 9% |
| Below 50 | Very low: often disordered regions | 17% |
What pLDDT means and how to read it
Associates with the striatin-interacting phosphatase and kinase (STRIPAK) core complex, forming the extended (SIKE1:SLMAP)STRIPAK complex (PubMed:29063833, PubMed:30622739). The (SIKE1:SLMAP)STRIPAK complex dephosphorylates STK3 leading to the inhibition of Hippo signaling and the control of cell growth (PubMed:29063833, PubMed:30622739). May play a role during myoblast fusion (By similarity)
Homodimer. Interacts with myosin (By similarity). Interacts with SIKE1 and both associate with the STRIPAK core complex composed of PP2A catalytic and scaffolding subunits, the striatins (PP2A regulatory subunits), the striatin-associated proteins MOB4, STRIP1 and STRIP2, PDCD10 and members of the STE20 kinases, such as STK24 and STK26 (PubMed:29063833, PubMed:30622739). Interacts (via FHA…
Cell membrane, sarcolemma, Cytoplasm, myofibril, sarcomere, M line, Cytoplasm, myofibril, sarcomere, Z line, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Endoplasmic reticulum membrane, Mitochondrion membrane
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 6AR0 | X-ray | 1.08 Å | A=1-140 |
| 6AR2 | X-ray | 1.55 Å | A/B=1-140 |
| 6AKM | X-ray | 2.3 Å | B=167-226 |
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