6AKM: SLMAP-SIKE1 complex

Crystal structure of SLMAP-SIKE1 complex. Determined by X-ray diffraction at 2.3 Å resolution. Released 16 Jan 2019.

Method: X-ray diffraction
Resolution: 2.3 Å
Organism: Homo sapiens
Chains: 2
Atoms: 773
Mol. weight: 14.7 kDa
Released: 16 Jan 2019

Explore 6AKM in 3D Show helices and sheets RCSB PDB PDBe

Secondary structure: helices and β-sheets

6AKM contains 3 α-helices and 0 β-strands across 2 chains. Residue ranges use author residue numbering, as in the PDB file, from PDBe. To see them in 3D, choose the Cartoon representation with Secondary structure coloring: helices, sheets and coils get different colors.

Chain A: 1 helix, 0 β-strands

Element	Residues	Length	Sheet
α-helix	4-46	43

Chain B: 2 helices, 0 β-strands

Element	Residues	Length	Sheet
α-helix	164-199	36
α-helix	201-206	6

Molecules and chains

Molecule	Chains	Type	Length	Organism	UniProt
Suppressor of IKBKE 1	A	protein	65	Homo sapiens	Q9BRV8 (AlphaFold model)
Sarcolemmal membrane-associated protein	B	protein	64	Homo sapiens	Q14BN4 (AlphaFold model)

Sequence of entity 1 (A), FASTA

>6AKM_1 Suppressor of IKBKE 1 (chains A)
STMAIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGTALPDQYQEDASD
MKDMS

Sequence of entity 2 (B), FASTA

>6AKM_2 Sarcolemmal membrane-associated protein (chains B)
STMEQLSQYLQEALHREQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGN
QLQA

Primary citation

Architecture, substructures, and dynamic assembly of STRIPAK complexes in Hippo signaling. Tang, Y., Chen, M., Zhou, L. et al. Cell Discov (2019) 5:3-3. DOI 10.1038/s41421-018-0077-3 · PubMed

Other PDB entries of the same protein (UniProt Q9BRV8 (AlphaFold model), which also has an AlphaFold model), best resolution first:

6AKK 1.5 Å, Crystal structure of the second Coiled-coil domain of SIKE1
6AKL 1.75 Å, Crystal structure of Striatin3 in complex with SIKE1 Coiled-coil domain

Browse structure collections

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