Chromatin assembly factor 1 p55 subunit (Caf1-55) is a 430-residue protein from Drosophila melanogaster. This is its AlphaFold structure prediction, created 1 Aug 2025. UniProt accession: Q24572.
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The mean pLDDT of this model is 91.3 (very high overall). pLDDT is AlphaFold's per-residue confidence score from 0 to 100. In MolViewer, choose the B-factor color scheme to color the model by pLDDT, because AlphaFold stores it in the B-factor column.
| pLDDT band | Meaning | Share of residues |
|---|---|---|
| Above 90 | Very high: backbone and side chains are usually accurate | 84% |
| 70 to 90 | Confident: backbone generally right | 5% |
| 50 to 70 | Low: treat with caution | 7% |
| Below 50 | Very low: often disordered regions | 5% |
What pLDDT means and how to read it
Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the nucleosome remodeling and deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the nucleosome remodeling factor (NURF) complex, which catalyzes ATP-dependent nucleosome sliding and facilitates…
Probably binds directly to helix 1 of the histone fold of histone H4, a region that is not accessible when H4 is in chromatin (Probable). Self associates (PubMed:15516265). Associates with chromatin (PubMed:9419341). Component of the CAF-1 complex, composed of Caf1-55, Caf1-105 and Caf1-180; within the CAF-1 complex, Caf1-180 interacts directly with both Caf1-55 and Caf1-105 (PubMed:11533245).…
Nucleus
Compare the prediction with experimentally determined structures of the same protein:
| PDB ID | Method | Resolution | Chains and residues |
|---|---|---|---|
| 2XYI | X-ray | 1.75 Å | A=1-430 |
| 2YB8 | X-ray | 2.3 Å | B=1-418 |
| 2YBA | X-ray | 2.55 Å | A/B=1-418 |
| 3C99 | X-ray | 2.9 Å | A=1-430 |
| 3C9C | X-ray | 3.2 Å | A=1-430 |
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